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71.
Dubroqua S Boison D Feldon J Möhler H Yee BK 《Neurobiology of learning and memory》2011,96(2):218-229
Behavioural characterisation of transgenic mice has been instrumental in search of therapeutic targets for the modulation of cognitive function. However, little effort has been devoted to phenotypic characterisation across environmental conditions and genomic differences such as sex and strain, which is essential to translational research. The present study is an effort in this direction. It scrutinised the stability and robustness of the phenotype of enhanced Pavlovian conditioning reported in mice with forebrain neuronal deletion of glycine transporter 1 by evaluating the possible presence of sex and circadian dependency, and its consistency across aversive and appetitive conditioning paradigms. The Pavlovian phenotype was essentially unaffected by the time of testing between the two circadian phases, but it was modified by sex in both conditioning paradigms. We observed that the effect size of the phenotype was strongest in female mice tested during the dark phase in the aversive paradigm. Critically, the presence of the phenotype in female mutants was accompanied by an increase in resistance to extinction. Similarly, enhanced conditioned responding once again emerged solely in female mutants in the appetitive conditioning experiment, which was again associated with an increased resistance to extinction across days, but male mutants exhibited an opposite trend towards facilitation of extinction. The present study has thus added hitherto unknown qualifications and specifications of a previously reported memory enhancing phenotype in this mouse line by identifying the determinants of the magnitude and direction of the expressed phenotype. This in-depth comparative approach is of value to the interpretation of behavioural findings in general. 相似文献
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73.
Owing to the sexuation of occupations associating technical attributes with men and relational skills with women, the latter are less numerous in professions where driving is involved. The negative stereotype associating women with poor driving skills is thus likely to have a cognitive and behavioral impact. According to the model of the stereotype threat, could activation of the threat inhibit the performance of women in a Highway Code test? After performing an association task that demonstrated a largely negative stereotype, 56 female students took a Highway Code test in two conditions: an experimental condition where the stereotype was activated by a comparison between men and women (N = 17); and a control condition without activation (N = 39). Subjects performed less well in the experimental condition, demonstrating the expected effects of the stereotype threat. 相似文献
74.
Several studies have demonstrated that as listeners hear sentences describing events in a scene, their eye movements anticipate upcoming linguistic items predicted by the unfolding relationship between scene and sentence. While this may reflect active prediction based on structural or contextual expectations, the influence of local thematic priming between words has not been fully examined. In Experiment 1, we presented verbs (e.g., arrest) in active (Subject–Verb–Object) sentences with displays containing verb-related patients (e.g., crook) and agents (e.g., policeman). We examined patient and agent fixations following the verb, after the agent role had been filled by another entity, but prior to bottom-up specification of the object. Participants were nearly as likely to fixate agents “anticipatorily” as patients, even though the agent role was already filled. However, the patient advantage suggested simultaneous influences of both local priming and active prediction. In Experiment 2, using passive sentences (Object–Verb–Subject), we found stronger, but still graded influences of role prediction when more time elapsed between verb and target, and more syntactic cues were available. We interpret anticipatory fixations as emerging from constraint-based processes that involve both non-predictive thematic priming and active prediction. 相似文献
75.
It is widely believed that advantages of hemispheric asymmetries originated in better cognitive processing, hence it is often implied that the relationship between hemispheric asymmetry and cognitive performance is linearly positive: the higher the degree of lateralization in a specific cognitive domain, the better the performance in a corresponding task. Yet, the empirical evidence for this notion is mixed and the statistical methods to analyze this relationship have been criticized. The present study therefore investigated the relationship between hemispheric asymmetries and cognitive performance in two behavioral tasks (a left-lateralized word-matching task and a right-lateralized face-decision task) in 230 participants (140 women, 90 men) by using two different approaches. Both methods correspondingly revealed that a relationship between hemispheric asymmetries and cognitive performance does exist. Contrary to a positive (linear) relationship however, the data could be best described by an inverted U-shaped curve. Although the optimal degree of lateralization seemed to be task-specific, a slight or moderate degree of hemispheric asymmetry achieved best cognitive performance in all tasks. Moreover, performances deteriorated towards extreme ends of lateralization (i.e., participants with either extreme left or right hemispheric biases). Taken together, the present study provides evidence against the notion that higher lateralization is related to enhanced cognitive performance. 相似文献
76.
77.
Marc Wittmann Estibaliz Arce Carmen Santisteban 《Personality and individual differences》2008,45(7):618-623
Individual differences in personality traits such as impulsivity and trait anger as well as environmental variables have an impact on aggressiveness. We tested a model incorporating the related variables of impulsiveness, trait anger, and aggression and incorporated the possible mediating influences of leisure-time activities. Regression analyses of data from 1129 pre-adolescents and 1093 adolescents (55.4% females) from a study evaluating the Spanish version of the Buss and Perry aggression questionnaire (AQ; Santisteban, Alvarado, & Recio, 2007) showed a relation between impulsiveness (Barratt Impulsiveness Scale) and aggression (AQ). Trait anger (Spielberger’s State-Trait Anger Expression Inventory), the time spent watching TV and playing video games, and the time spent doing homework (all related to impulsiveness) also are related to physical, as well as verbal aggression (with low to moderate coefficients). Multiple mediation analyses confirm that media violence exposure and homework, respectively, can have aggravating and attenuating effects on self-reported aggression. These results provide key variables for longitudinal studies which could reveal the causal nature of the results found with our cross-sectional design. 相似文献
78.
Self-presentation and gender on MySpace 总被引:1,自引:0,他引:1
Adriana M. Manago Michael B. Graham Patricia M. Greenfield Goldie Salimkhan 《Journal of applied developmental psychology》2008,29(6):446
Within the cultural context of MySpace, this study explores the ways emerging adults experience social networking. Through focus group methodology, the role of virtual peer interaction in the development of personal, social, and gender identities was investigated. Findings suggest that college students utilize MySpace for identity exploration, engaging in social comparison and expressing idealized aspects of the selves they wish to become. The public nature of self and relationship displays introduce feedback mechanisms by which emerging adults can legitimize images as associated with the self. Also, male–female differences in self-presentation parallel, and possibly intensify, gender norms offline. Our study suggests that social networking sites provide valuable opportunities for emerging adults to realize possible selves; however, increased pressure for female sexual objectification and intensified social comparison may also negatively impact identity development. A balanced view, presenting both opportunities and drawbacks, should be encouraged in policies regarding youth participation in social networking sites. 相似文献
79.
There is abundant evidence from behavioral and neurophysiological experiments for the distinction of natural versus artifactual categories and a gender-specific difference: women’s performances in cognitive tasks increase when natural categories are used, whereas men’s performances increase with artifactual categories. Here, we used the semantic priming paradigm to study retrieval processes by presenting category labels as primes and exemplars as targets. Overall, in two experiments we found larger priming effects for natural than for artifactual categories. In addition, females showed positive priming effects for natural but negative effects for artifactual categories, whereas males showed positive priming effects for both categories. This pattern matches with that from other tasks and can be interpreted as evidence that the findings from these other tasks are, at least partially, indeed due to different representations or processing modes for males and females and not (exclusively) due to—for example—different familiarity with a category. In a further experiment, we showed that the found pattern for females can be manipulated by focusing on perceptual vs. functional features. The results can be interpreted as first evidence that there are (eventually in addition to different “crystallized” semantic structures) specific default processing modes that differ for males and females. 相似文献
80.
To successfully infer a speaker's emotional state, diverse sources of emotional information need to be decoded. The present study explored to what extent emotional speech recognition of 'basic' emotions (anger, disgust, fear, happiness, pleasant surprise, sadness) differs between different sex (male/female) and age (young/middle-aged) groups in a behavioural experiment. Participants were asked to identify the emotional prosody of a sentence as accurately as possible. As a secondary goal, the perceptual findings were examined in relation to acoustic properties of the sentences presented. Findings indicate that emotion recognition rates differ between the different categories tested and that these patterns varied significantly as a function of age, but not of sex. 相似文献