Does sound stimulation have additive effects on cognitive-behavioral treatment of chronic tinnitus?

Psychological and physiological habituation are major goals in the treatment of patients suffering from chronic tinnitus. This study evaluates whether sound stimulation provided by use of low level white noise generators (NG) enhances the effects of cognitive-behavioral treatment (CBT). 124 outpatients with tinnitus of >6 months received manualized group treatment and were randomly assigned to the NG/no NG conditions. Those with moderate tinnitus-related distress obtained four sessions focusing on education, while severely distressed subjects were treated according to a full 10-session CBT program. Outcome was assessed at post-treatment and at 6- and 18-month follow-up. No additive effects due to the NGs could be demonstrated. All groups improved significantly on measures of tinnitus-related distress, dysfunctional cognitions, general psychopathology, depression, hypochondriasis and psychosocial functioning. Beneficial effects of the NGs were only observed for patients with concurrent tinnitus and hyperacusis. As systematic physical stimulation of the auditory system does not further improve the effects of CBT, the importance and strength of psychological interventions are emphasized. The clinical relevance of recently developed "retraining" approaches accentuating physical stimulation should be reconsidered.     

Repetitive transcranial magnetic stimulation may induce language switching in bilingual patients

The dorsolateral prefrontal cortex (DLPFC) may participate in the process of language switching in multilingual individuals. We present two cases of bilingual patients who experienced unexpected language switching after receiving high-frequency, repetitive transcranial magnetic stimulation (rTMS) to the left DLPFC as a treatment for major depression. These preliminary findings support the role of the DLPFC in language switching in polyglots and highlight the potential value of rTMS for non-invasively investigating language function in humans. Further investigation is warranted.     

Heritage space,multiple temporalities,and the reproduction of Guangzhou Overseas Chinese Village

This paper investigates the everyday experiences of long-term residents during the urban heritage revitalization process of Guangzhou Overseas Chinese Village (GOCV) as China's first overseas Chinese village. Drawing upon insights from the recent theories of multiple temporalities, this paper argues that the everyday sensory experiences of long-term residents during the urban heritage revitalization process can be understood through three interconnected temporal modes (past, present, and future). These modes reflect the sociopolitical context of different periods and influence the everyday rhythms and practices of community residents. Specifically, regarding the past, patriotic fervor, a shared identity, and the experience of living collectively have created a “happy home for returned overseas Chinese”. In terms of the present, the market-oriented reform and commodification of housing has had a profound impact on the built forms and meaning systems of the neighborhood, leading to long-term residents' nostalgia for the past and resistance to present changes in the everyday rhythms. Lastly, based on an envisioned future, long-term residents carry out specific preservation practices to maintain and enhance their place identity. This article explores the approaches to enrich the urban heritage research by illuminating the importance of temporality for understanding the spatial (re)production of living urban heritage.     

The behavioral complications of pallidal stimulation: a case report

We report a case of recurrent manic episodes associated with chronic deep brain stimulation (DBS) targeting globus pallidus (GP) in the treatment of Parkinson's disease (PD). Cardinal PD symptoms and dyskinesia improved with DBS, and neuropsychological testing found improvements in visuospatial measures associated with left DBS and in verbal memory with right DBS when compared to the patient's preoperative baseline. Under conditions of right, left, and bilateral DBS, the patient experienced bouts of mania and hypomania lasting several days at a time. Positron emission tomography (PET) with (15)O-labeled water was performed after his first manic episode under four conditions: no stimulation, right DBS, left DBS, and bilateral DBS. Although no manic switch occurred during the course of the PET study, all three DBS conditions were associated with decreases in regional flow in the left parahippocampus and hippocampus and right mid-cingulate gyrus. Increases in flow in left inferior frontal area, bilateral insula, dorsolateral prefrontal cortex, and cuneus were common to all DBS conditions. GP stimulation in PD may be associated with behavioral and cognitive effects. Distributed blood flow changes observed with pallidal DBS support a role for the pallidum in cognition and affective regulation.     

腹内侧前额叶在内隐认知重评中的因果作用

情绪调节对维持个体心理健康、适应社会生活十分重要, 然而以往研究主要关注外显情绪调节, 目前我们对内隐情绪调节的认知神经机制的了解还非常有限。为揭示内隐情绪调节的核心脑区, 本研究使用句子整理任务启动内隐认知重评, 并采用经颅直流电刺激(transcranial direct current stimulation, tDCS)激活内侧前额叶特别是腹内侧前额叶(ventromedial prefrontal cortex, vmPFC), 考察该脑区在内隐情绪调节中的因果作用。结果表明, vmPFC被激活的被试组(实验组, n = 40)在内隐认知重评启动条件下比tDCS伪刺激组(对照组, n = 40), 在观看负性图片时报告了更少的负性情绪, 同时负性图片诱发的晚正成分(late positive potential, LPP)波幅更低(LPP是情绪体验强度的客观指标)。同时, 实验组比对照组在观看负性图片时表现出更低的枕区P1波幅(P1为早期视觉注意程度的客观指标)。以上结果说明, 激活以vmPFC为代表的内侧前额叶不但能增强内隐情绪调节的效果, 还能减少被试对负性刺激的早期注意分配。本研究是采用tDCS技术考察启动引起的内隐情绪调节的首次尝试, 研究结果不但表明了以vmPFC为代表的内侧前额叶在内隐认知重评中的关键作用, 还为临床应用研究指出了增强内隐情绪调节能力的神经调控潜在靶点。     

The backstage of urban ambiances: When atmospheres pervade everyday experience

This paper explores a new way of designing and experimenting with the city. How are we to conceptualize the changes in contemporary cities on the basis of their ambiances? What about the sensory and emotional production of urban territories? What is at stake when our aim is no longer to design space but also to install an atmosphere? In order to answer such questions, rather than offering a formal definition of what an ambiance may be, I intend to show from what it proceeds, on what it is based, what it produces and transforms in urban life. The focus is exploring five ambiance operating modes in the province of urban design: establishing the sensory as a field of action, composing with affective tonalities, giving consistency to urban situations, maintaining spaces over time and playing with imperceptible transformations. Each of these operating modes can account for how a physical environment manages to become a lived ambiance, how a world of built forms manages to become a world of sensory atmospheres. Starting with the sensory environment itself, I show how it is increasingly becoming a domain of design and research. Then I emphasize on the role of affect in everyday urban situations and daily social activities. Thirdly I explore the pervasive character of an ambiance and question its capacity to unify an experience. I continue by pointing out the temporal dynamic of an ambiance and the necessity to sustain a sense of continuity of the environment. Finally I emphasize on the importance of micro-phenomena in the quality and immersive power of an ambiance. These five operating modes of ambiance enables us to focus on the very ordinary sensory fabric of urban life and its issues.     

Extra‐powerful on the visuo‐perceptual space,but variable on the number space: Different effects of optokinetic stimulation in neglect patients

We studied the effects of optokinetic stimulation (OKS; leftward, rightward, control) on the visuo‐perceptual and number space, in the same sample, during line bisection and mental number interval bisection tasks. To this end, we tested six patients with right‐hemisphere damage and neglect, six patients with right‐hemisphere damage but without neglect, and six neurologically healthy participants. In patients with neglect, we found a strong effect of leftward OKS on line bisection, but not on mental number interval bisection. We suggest that OKS influences the number space only under specific conditions.     

Mapping the structure of perceptual and visual–motor abilities in healthy young adults

The ability to quickly detect and respond to visual stimuli in the environment is critical to many human activities. While such perceptual and visual–motor skills are important in a myriad of contexts, considerable variability exists between individuals in these abilities. To better understand the sources of this variability, we assessed perceptual and visual–motor skills in a large sample of 230 healthy individuals via the Nike SPARQ Sensory Station, and compared variability in their behavioral performance to demographic, state, sleep and consumption characteristics. Dimension reduction and regression analyses indicated three underlying factors: Visual–Motor Control, Visual Sensitivity, and Eye Quickness, which accounted for roughly half of the overall population variance in performance on this battery. Inter-individual variability in Visual–Motor Control was correlated with gender and circadian patters such that performance on this factor was better for males and for those who had been awake for a longer period of time before assessment. The current findings indicate that abilities involving coordinated hand movements in response to stimuli are subject to greater individual variability, while visual sensitivity and occulomotor control are largely stable across individuals.     

The effect of a simulated hearing loss on performance of an auditory memory task in driving

Hearing loss has been shown to exacerbate the effect of auditory distraction on driving performance in older drivers. This study controlled for the potentially confounding factor of age-related cognitive decrements, by applying a simulated hearing loss in young, normally hearing individuals. Participants drove a simulated road whilst completing auditory tasks under simulated hearing loss or normal hearing conditions. Measures of vehicle control, eye movements and auditory task performance were recorded. Results showed that performing the auditory tasks whilst driving resulted in more stable lateral vehicle control and a reduction in gaze dispersion around the road centre. These trends were not exacerbated by simulated hearing loss, suggesting no effect of hearing loss on vehicle control or eye movement patterns during auditory task engagement. However, a small effect of simulated hearing loss on the performance of the most complex auditory task was observed during driving, suggesting that the use of sound-based in-vehicle systems may be problematic for hearing impaired individuals. Further research incorporating a wider variety of driving scenarios and auditory tasks is required in order to confirm the findings of this study.