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111.
Oliver Gruber Tobias Melcher Esther K. Diekhof Susanne Karch Peter Falkai Thomas Goschke 《Brain and cognition》2009,69(3):559-564
Background monitoring is a necessary prerequisite to detect unexpected changes in the environment, while being involved in a primary task. Here, we used fMRI to investigate the neural mechanisms that underlie adaptive goal-directed behavior in a cued task switching paradigm during real response conflict or, more generally, when expectations on the repetitive features of the environment were violated. Unexpected changes in sensory stimulus attributes in the currently unattended stimulus dimension thereby led to activations in a bilateral network comprising inferior lateral frontal, intraparietal, and posterior medial frontal brain regions, independent of whether these attributes elicited a factual response conflict or not. This fronto-parietal network may thus play an important role in adaptive responding to potentially significant events outside the current focus of attention. 相似文献
112.
In recent years, neuromodulation of the cervical spinal circuitry has become an area of interest for investigating rhythmogenesis of the human spinal cord and interaction between cervical and lumbosacral circuitries, given the involvement of rhythmic arm muscle activity in many locomotor tasks. We have previously shown that arm muscle vibrostimulation can elicit non-voluntary upper limb oscillations in unloading body conditions. Here we investigated the excitability of the cervical spinal circuitry by applying different peripheral and central stimuli in healthy humans. The rationale for applying combined stimuli is that the efficiency of only one stimulus is generally limited. We found that low-intensity electrical stimulation of the superficial arm median nerve can evoke rhythmic arm movements. Furthermore, the movements were enhanced by additional peripheral stimuli (e.g., arm muscle vibration, head turns or passive rhythmic leg movements). Finally, low-frequency transcranial magnetic stimulation of the motor cortex significantly facilitated rhythmogenesis. The findings are discussed in the general framework of a brain-spinal interface for developing adaptive central pattern generator-modulating therapies. 相似文献
113.
In 1986 I began research to address the relationship between early child abuse and neglect and later deliquent and violent criminal behavior using a prospective cohort design. The relationship is not inevitable, suggesting an opportunity for long-range violence prevention through appropriate early intervention. Here, I briefly describe how childhood victimization and violent criminal behavior are related and illustrate a number of promising strategies and opportunities to intervene. Finally, I offer five principles to guide interventions: (1) the earlier the intervention, the better; (2) don't neglect neglected children; (3) one size does not fit all; (4) surveillance—a double-edged sword; and (5) accessibility to resources. Rather than focusing on responses to child abuse or neglect in court proceedings that “treat” offenders, primary prevention efforts should target childhood victims to reduce their risk of becoming offenders in the future. 相似文献
114.
According to the object-based view, visual attention can be deployed to "objects" or perceptual units, regardless of spatial locations. Recently, however, the notion of object has also been extended to the auditory domain, with some authors suggesting possible interactions between visual and auditory objects. Here we show that task-irrelevant auditory objects may affect the deployment of visual attention, providing evidence that crossmodal links can also occur at an object-based level. Hence, in addition to the well documented control of visual objects over what we hear, our findings demonstrate that, in some cases, auditory objects can affect visual processing. 相似文献
115.
The background page on which a stimulus is presented can influence the allocation of attention to that stimulus. The purpose of this study was to learn if there are hemispheric asymmetries in how background distraction affects attentional processing. Asymmetries were investigated by having right eye dominant subjects perform line bisections and manipulating the side of background distraction (right versus left), the eye of regard (right versus left), and the type of attention allocated (focal versus global). Overall subjects bisected lines to the left of center (pseudoneglect) and when viewing with the right eye (versus left) deviated more to the left. Subjects had more background distraction when viewing symbol than solid lines. Although overall, bias did not differ with the side of background distraction or the line being on one side or the other, when subjects viewed symbol, but not solid lines, this leftward bias was increased when the line was displaced to the right, thereby increasing the size of the left sided background. These findings suggest that when engaging the left hemisphere by using focused attention and placing the line on the right side, there is more distraction than when the right hemisphere is engaged. 相似文献
116.
Forty-five adolescent boys from abusive and depriving homes were not doing well in positive peer culture residential care. Despite their backgrounds, given a modified form of the Relational Ethics Scale, they indicated that their relational life with their families of origin was trustworthy, fair, and worthy of continued devotion. In contrast, on the Firo-B these same boys demonstrated distrust of others outside of their families and an unwillingness to get involved. These results support the inference from contextual family theory that peer group interventions cannot bypass identification and resolution of the injustices that took place in the family of origin.This project was fully supported by Teen Ranch, Inc., Marlette, MI 48453. 相似文献
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118.
Spatial analysis after perinatal stroke: patterns of neglect and exploration in extra-personal space
This study was conducted to determine whether school-aged children who had experienced a perinatal stroke demonstrate evidence of persistent spatial neglect, and if such neglect was specific to the visual domain or was more generalized. Two studies were carried out. In the first, 38 children with either left hemisphere (LH) or right hemisphere (RH) damage and 50 age-matched controls were given visual cancellation tasks varying in two factors: target stimuli and stimulus array. In the second study, tactile neglect was evaluated in 41 children with LH or RH damage and 72 age-matched controls using a blindfolded manual exploration task. On the visual cancellation task, LH subjects omitted more target stimuli on the right, but also on the left, compared with controls. Children with RH lesions also produced a larger number of omissions on both the left and right sides than controls, but with poorer performance on the left. On the manual exploration task, LH children required significantly longer times to locate the target on both sides of the board than did controls. RH children had significantly prolonged search times on the left side, but not on the right, compared with controls. In both tasks, LH subjects employed unsystematic search strategies more often than both control and RH children. The search strategy of RH children also tended to be erratic when compared to controls, but only in the random arrays of the visual cancellation tasks; structure of the target stimuli improved their organization. These results demonstrate that children with early LH brain damage display bilateral difficulties in visual and tactile modalities; a pattern that is in contrast to that seen in adults with LH damage. This may result from disorganized search strategies or other subtle spatial or attentional deficits. Results of performance of RH children suggests the presence of contralateral neglect in both the visual and tactile modalities; a finding that is similar to the neglect in adult stroke patients with RH lesions. The fact that deficits in spatial attention and organizational strategies are present after very early focal damage to either the LH or the RH broadens our understanding of the differences in functional lateralization between the immature and mature brain. These results also add to evidence for limitations to plasticity in the developing brain. Our findings may have therapeutic and rehabilitative implications for the management of children with early focal brain lesions. 相似文献
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120.
为探讨儿童期情感忽视与大学生抑郁的关系,以及控制感和情绪调节自我效能感在其中的中介作用,采用儿童期创伤问卷、控制感量表、情绪调节自我效能感量表和贝克抑郁量表(第2版),对重庆市两所高校共837名大学生进行调查。结果显示:(1)儿童期情感忽视显著正向预测大学生抑郁;(2)控制感、情绪调节自我效能感在儿童期情感忽视与抑郁之间起独立中介作用;(3)控制感与情绪调节自我效能感在儿童期情感忽视与抑郁之间起链式中介作用,且情绪调节自我效能感各维度的效应皆成立。本研究考察了儿童期情感忽视对抑郁的影响及其作用机制,为家庭教养方式的改善及大学生抑郁问题的预防与干预提供了实践启示。 相似文献