I. V. Zavadskii and the beginnings of behavioral pharmacology: an historical note and translation.

I. V. Zavadskii, who worked in Pavlov's laboratory between 1907 and 1909, performed a study that has many of the characteristics of modern behavioral pharmacology. He studied the effects of alcohol, morphine, cocaine and caffeine on the conditioned salivary reflex. A translation of his paper and some brief comments on his life are presented.     

Extinction of likes and dislikes: effects of feature-specific attention allocation

The evaluative conditioning (EC) effect refers to the change in the liking of a neutral stimulus (conditioned stimulus, CS) due to its pairing with another stimulus (unconditioned stimulus, US). We examined whether the extinction rate of the EC effect is moderated by feature-specific attention allocation. In two experiments, CSs were abstract Gabor patches varying along two orthogonal, perceptual dimensions (i.e. spatial frequency and orientation). During the acquisition phase, one of these dimensions was predictive of the valence of the USs. During the extinction phase, CSs were presented alone and participants were asked to categorise the CSs either according to their valence, the perceptual dimension that was task-relevant during the acquisition phase, or a perceptual dimension that was task-irrelevant during the acquisition phase. As predicted, explicit valence measures revealed a linear increase in the extinction rate of the EC effect as participants were encouraged to assign attention to non-evaluative stimulus information during the extinction phase. In Experiment 1, Affect Misattribution Paradigm (AMP) data mimicked this pattern of results, although the effect just missed conventional levels of significance. In Experiment 2, the AMP data revealed an increase of the EC effect if attention was focused on evaluative stimulus information. Potential mechanisms to explain these findings are discussed.     

Early behaviour and its relation to behaviour at 3 years

In 34 healthy 1-month-old infants sleep, waking, crying and conditioning were analysed in detail. Intellectual functioning and coping with an unfamiliar situation were assessed at the age of 3 years. Likewise, the social environment including mother-infant interaction was considered. The majority of sleep and waking parameters assessed during the first month did not correlate with outcome data at 3 years. Rather, it was those concerning conditioning at 1 month that significantly correlated with coping in an unfamiliar situation at 3 years, a finding in accordance with neurophysiological concepts concerning stimulus sensitivity. More sensitive infants at 1 month had problems in coping with an unfamiliar situation at 3 years. In the light of these results we suggest that factors related to central nervous system processes play a role in coping with unfamiliar situations.     

Do different types of US produce similar evaluative conditioning? An examination with contingency-awareness and cognitive load

Evaluative conditioning (EC) refers to a modulation in the liking of a neutral stimulus after it has been paired with an unconditioned stimulus (US). Previous studies have uncovered some of the mechanisms responsible for EC, but many parameters remain unknown. The study addresses two questions: Is the amplitude of EC and the impact of cognitive variables are the same for different types of US? We compared three types of US: shocks, single images and multiple semantically related images. This conditioning occurred while participants maintained a concurrent cognitive load, or not. Our results indicate that all types of US produced a significant EC of similar amplitude. Furthermore, the two cognitive variables had a similar impact across all types of US. Specifically, contingency-awareness was related to the amplitude of EC, particularly in the cognitive load group. Our results illustrate the importance of within study comparisons to assess different parameters on EC.