A Review of the Types of Scientific Misconduct in Biomedical Research

Biomedical research has increased in magnitude over the last two decades. Increasing number of researchers has led to increase in competition for scarce resources. Researchers have often tried to take the shortest route to success which may involve performing fraudulent research. Science suffers from unethical research as much time, effort and cost is involved in exposing fraud and setting the standards right. It is better for all students of science to be aware of the methods used in fraudulent research so that such research can be detected early. Biomedical research is one area that seems to have attracted maximum numbers of fraudulent researchers; hence this article devotes itself to biomedical research scenario.     

The ontological commitments of inconsistent theories

In this paper I present an argument for belief in inconsistent objects. The argument relies on a particular, plausible version of scientific realism, and the fact that often our best scientific theories are inconsistent. It is not clear what to make of this argument. Is it a reductio of the version of scientific realism under consideration? If it is, what are the alternatives? Should we just accept the conclusion? I will argue (rather tentatively and suitably qualified) for a positive answer to the last question: there are times when it is legitimate to believe in inconsistent objects.     

WHY I AM AN ACCOMMODATIONIST AND PROUD OF IT

There is a strong need of a reasoned defense of what was known as the “independence” position of the science–religion relationship but that more recently has been denigrated as the “accommodationist” position, namely that while there are parts of religion—fundamentalist Christianity in particular—that clash with modern science, the essential parts of religion (Christianity) do not and could not clash with science. A case for this position is made on the grounds of the essentially metaphorical nature of science. Modern science functions because of its root metaphor of the machine: the world is seen in mechanical terms. As Thomas Kuhn insisted, metaphors function in part by ruling some questions outside their domain. In the case of modern science, four questions go unasked and hence unanswered: Why is there something rather than nothing? What is the foundation of morality? What is mind and its relationship to matter? What is the meaning of it all? You can remain a nonreligious skeptic on these questions, but it is open for the Christian to offer his or her answers, so long as they are not scientific answers. Here then is a way that science and religion can coexist.     

Evolving research misconduct policies and their significance for physical scientists

Scientific misconduct includes the fabrication, falsification, and plagiarism (FFP) of concepts, data or ideas; some institutions in the United States have expanded this concept to include “other serious deviations (OSD) from accepted research practice.” It is the absence of this OSD clause that distinguishes scientific misconduct policies of the past from the “research misconduct” policies that should be the basis of future federal policy in this area. This paper introduces a standard for judging whether an action should be considered research misconduct as distinguished from scientific misconduct: by this standard, research misconduct must involve activities unique to the practice of science and must have the potential to negatively affect the scientific record. Although the number of cases of scientific misconduct is uncertain (only the NIH and the NSF keep formal records), the costs are high in terms of the integrity of the scientific record, diversions from research to investigate allegations, ruined careers of those eventually exonerated, and erosion of public confidence in science. Existing scientific misconduct policies vary from institution to institution and from government agency to government agency; some have highly developed guidelines that include OSD, others have no guidelines at all. One result has been that the federal False Claims Act has been used to pursue allegations of scientific misconduct. As a consequence, such allegations have been adjudicated in federal courts, rather than judged by scientific peers. The federal government is now establishing a first-ever research misconduct policy that would apply to all research funded by the federal government regardless of which agency funded the research or whether the research was carried out in a government, industrial or university laboratory. Physical scientists, who up to now have only infrequently been the subject of scientific misconduct allegations, must nonetheless become active in the debate over research misconduct policies and how they are implemented since they will now be explicitly covered by this new federal wide policy. Disclaimer: The authors are grateful for the support for conduct of this research provided by the United States Department of Energy (DOE). The views expressed in this paper are solely those of the authors and were formed and expressed without reference to positions taken by DOE or the Pacific Northwest National Laboratory (PNNL). The views of the authors are not intended either to reflect or imply positions of DOE or PNNL.     

创新和知识经济与促肝细胞生长素的研制

创新是一个民族进步的灵魂,是科研工作的核心,是知识经济对知识的根本要求。促肝细胞生长素是治疗肝炎的有效药物,该药物研制成功的关键在于创新。纵观其研制过程的创新思路与实践,将有助于我们更新科研观念,增加创新意识。     

Psychology between science and common sense: William James and the problems of psychological language in the Principles

The suspicion that language can become an obstacle to human knowledge is not new in the Western intellectual tradition. Following the empiricist legacy, many authors have suggested the perils and pitfalls of common sense language for science. Applied to psychology, this leads to the issue of the reliability of psychological language for scientific psychology. William James, in his Principles of Psychology, was one of the first psychologists to address this problem explicitly. The goal of this paper is to situate his position and contrast it with contemporary debates over the status of folk psychology. The results indicate that James conceived of common sense psychology in a very complex manner, and pointed to a kind of illusion that remains ignored in the current literature, with negative consequences for psychology. I conclude by suggesting the relevance of James for contemporary debates in theoretical and philosophical psychology.     

Two Notions of Scientific Justification

Scientific claims can be assessed epistemically in either of two ways: according to scientific standards, or by means of philosophical arguments such as the no-miracle argument in favor of scientific realism. This paper investigates the basis of this duality of epistemic assessments. It is claimed that the duality rests on two different notions of epistemic justification that are well-known from the debate on internalism and externalism in general epistemology: a deontological and an alethic notion. By discussing the conditions for the scientific acceptability of empirical results, it is argued that intrascientific justification employs the deontological notion. Philosophical disputes such as those on scientific realism can by contrast be shown to rest on the alethic notion. The implications of these findings both for the nature of the respective epistemic projects and for their interrelation are explored.