人类行为遗传学的伦理问题

行为遗传学是试图定位与行为特性有关的特殊基因或基因组及了解基因与环境之间复杂关系的一种研究.行为遗传学是研究正常范围内的非病理变化,与人类疾病遗传学存在差异.行为遗传学研究面临许多伦理学问题,诸如,智力的遗传性,基因能否决定一切,生物社会学与人类文化评估,生命伦理学与行为遗传学的关系等,因此,对行为遗传学研究结果的阐述必须十分谨慎.     

结核病诊治进展与科技革命

现代科技革命极大地促进了结核病各方面的发展.微生物学和免疫学的发展,揭示了结核病的病因、发病机制、病理生理的本质,分子生物学技术使结核病的基础研究不仅停留在器官、细胞水平,而是深入到蛋白质、核酸、基因的水平;基因治疗的方法可望从根本上治疗结核病.高新技术的产物如X线照片、电子计算机断层扫描、纤维支气管镜检查和新药的出现等极大地提高了临床诊治的能力.借助于各种先进的医疗设备而进行精确的诊断,基因治疗将成为一种崭新的治疗手段.     

What will the future bring? Thoughts of children after missile bombardment

Abstract

We examined how cognitive views of the future relate to degree of exposure to trauma and to posttraumatic stress reactions in children. Following the experience of Scud missile bombardment during the Persian Gulf war, 492 Israeli pupils from grades 5, 7, and 10 from regions actually hit and from regions under threat but not hit, described what they thought life would be like next year for children of their age. Based on recent cognitive theories, it was expected that children who experienced higher levels of stress would also express more pessimistic views of the future. We found that children's dominant perception of the future was positive. However, children who expressed stronger postwar reactions also tended to have more pessimistic future views, especially in areas that were hit by missiles. Discussion focused upon views of the future as a direct consequence of the stress as well as a means of coping with stress.     

The Vatican and Europe: Political Theology and Ecclesiology in Papal Statements from Pius XII to Benedict XVI

The article examines the origins and evolution of the Vatican's political theology and ecclesiology for Europe from Pius XII (especially after the Second World War) and including the pontificates of John XXIII, Paul VI, John Paul II and Benedict XVI. It seeks to examine the continuities of the ‘Idea of Europe’ in papal thought against a background of changing political context – the end of the Second World War, the Cold War, the fall of the communist state system, the emergence of a united but diverse Europe after 1989. The political structures of the continent now include within its geographic sweep Western and Eastern Christian churches which, divided by tradition and modern history, find their relationship a key marker in the contemporary religious identity of Europe. This reality is a significant framework for Vatican thinking on Europe especially for John Paul II and Benedict XVI.     

Correspondence between children's and adults' ratings of stimulant-induced changes in ADHD behaviours in a crossover trial with medication-naive children

Correspondence between children's and adults' ratings of changes in ADHD behaviours was investigated in a paediatric ADHD stimulant crossover trial. Thirty-one children completed an ADHD self-report scale each week, and comparisons were made with an ADHD questionnaire completed by adults (combined parent and teacher ratings). Children's and adults' ratings demonstrated good internal consistency, were significantly associated with the assessment of ADHD behaviours in the placebo condition and showed comparable responsiveness to stimulants at the group level. Furthermore, a large and significant correlation was detected between the two sets of informants' ratings of changes from placebo to both methylphenidate and dextroamphetamine high-dosage conditions, but not from placebo to low-dosage conditions. Agreement in the categorization of best stimulant condition for individual children was significant, but modest from a clinical perspective. The results indicate that children's ratings correspond adequately with adults' ratings, and thus appear to be a complementary outcome measure.     

Differential impacts of age of acquisition on letter and semantic fluency in Alzheimer's disease patients and healthy older adults

The degree to which the typical age of acquisition (AoA) of words and word frequency have separable influences on verbal production tasks has been strongly debated. To examine the overlap between these factors in verbal fluency tasks, the performance of Alzheimer's disease (AD) patients (N?=?34) and normal elderly controls (N?=?36) was compared on semantic (e.g., vegetables) and letter (e.g., words that begin with F) fluency tasks. These comparisons revealed that words generated for the semantic fluency task had an earlier AoA while words generated for the letter fluency task had a higher word frequency. Differences in AoA between AD patients and controls were larger for semantic than letter fluency. These results suggest that AoA has an effect on verbal production that is independent of word frequency and that AoA has a semantic locus.     

Sport and the obligation of solidarity

The paper departs from an analysis of the case of Michelle Dumaresq, a transgender female downhill mountain biker who experienced marginalization within her sport. The analysis is based on Axel Honneth’s theory of recognition. The Dumaresq case is particularly relevant to Honneth’s ideas of solidarity, which provide insight into the dynamics of social integration. Honneth’s theory of recognition also provides a conceptual framework and a methodology that gives new perspectives on the ethical significance of sport. In the paper, an analysis is presented of the lack of solidarity experienced by Dumaresq. The argument is made that sport has a particular potential for realizing solidarity among its practitioners. Realizing solidarity however depends to a large degree upon that the rules of sport are perceived as fair and just. In the Dumaresq case, challenges to solidarity came from what her competitors considered to be unfair classification rules. Summing up, it is argued that, as long as the rules of a sport is perceived as fair and just, voluntary engagement gives rise not only to obligations on fair play but to a moral obligation on solidarity as well.     

Effects of Emotional Factors Upon Recall

Bendig's (1) Pittsburgh Scales of Social Extraversion-Introversion (SEI) and Emotionality (Em) were translated so that they were of appropriate reading difficulty for children as well as for adults. The revised scales correlated highly (both .90) with the Pittsburgh scales, and they had high test-retest reliabilities (.92 and .89). Data from samples representing third grade to college ages were presented for the revised scales. SEI-Em correlations were nonsignificant for most subsamples, indicating that the revised SEI-Em scales are independent. Scale means were stable across ages. The revised scales should be considered as research instruments, since more representative normative data and validity data are still required. The scales should, though, facilitate developmental research in extraversion and emotionality.     

‘Wholeness,Dignity and the Ageing Self’: A Conversation Between Philosophy and Theology

SUMMARY

Winifred Wing Han Lamb: My philosophical interest straddles the areas of education, religion and theology. As a teacher involved in school philosophy programs, I have also been interested in the philosophy of childhood and particularly in the recurring notion of the ‘whole child’ in education. In considering what ‘wholeness’ could mean for children's education, I have also been led to consider what meaning it holds for the self through the ‘changing scenes’ of life, especially in the face of the challenges of ageing.

The notion of ‘wholeness’ holds an intuitive appeal and invites articulation of the deep truths of our faith with respect to persons in all ‘sorts and conditions.’ In section one of this chapter, I attempt that articulation. But this conversation needs to be complementary. Our chapter is the beginning of a dialogue between philosophy and theology in which both affirm the ageing self in the light of the human search for wholeness and dignity.

Heather Thomson: My theological research into humanity as an image of God led me to inquire about the way in which we could speak meaningfully of ageing and dying in terms of imaging God. This challenged how God-likeness was to be understood in relation to glory, honour and power, terms associated with imaging God and exerting dominion. In searching for a theological view of the self that would confer dignity on the ageing, I was led into conversation with various philosophies of the self, some very helpful for my task.

It seems to me that, if ageing people are to be counted as having dignity and worth, and not discounted, then one's theory of the human person was significant. In pondering the issue, it appeared that a conversation between philosophy and theology would be fruitful. Hence, this joint paper. We each speak from our own discipline but find resonance with each other's work. We see this as a first step in a constructive conversation.     

Consider the Children

Summary

In this article, we consider interventions for children exposed to family violence in light of the research on children's problems associated with witnessing family violence. Next, we review risk and protective factors related to these children's adjustment with the view that all children are not similarly affected by exposure to family violence. Against this background, we then move to consider directions for interventions from a systemic perspective. We take into account not only the exposure to interactions between their mother and father, but also children's relationships with their mother, father, and siblings, as well as within broader systems such as the peer group, the school, and the community. We consider the critical challenges within each of these important systems for children exposed to family violence, and we propose some potential interventions to address the problems. Finally, we summarize an evaluation of an intervention that incorporates some of the elements identified by a systemic perspective. The evaluation revealed a significant improvement in children's self-reports of depression and anxiety over the course of the program. Mothers rated their children as significantly improved in emotional and hyperactive behaviour problems. There was no relation between mothers' involvement in counselling and children's improvement. Overall, the results suggest that the Peer Group Counselling Program effectively provided support to children exposed to family violence. Finally, we discuss the steps necessary to support children and families in moving toward violence-free lives.