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641.
When designing new Advanced Driver Assistance Systems (ADAS), the existing guidelines like the RESPONSE 3 Code of Practice imply intense testing of the system prior series production. Within the EU-FP7-Project ISi-PADAS a new methodology of risk based design has been established which includes an integrated simulation platform. This integration enables intense testing of new prototypes in an accelerated way and therefore enhances the design process while directly combining the simulation results with a risk matrix.This paper describes the new methodology while focussing on the software framework and the procedure of risk assessment in detail. It shows the general approach as well as the appropriate steps taken for an ADAS prototype developed in the context of ISi-PADAS.  相似文献   
642.
Objective: Oesophageal cancer is an increasingly prevalent disease with a demanding post-curative treatment recovery period and sustained longer-term effects. Although post-curative treatment is a key transitionary period, the process of psychological adjustment for the individual is under-researched which limits the evidence base to inform supportive care. The aim of this study was to understand the process of adjustment for oesophageal cancer patients post-curative treatment, in particular the beliefs participants hold regarding their condition and how these are appraised against their experience.

Design: Serial interviews were undertaken with six oesophageal cancer patients who have recently completed curative treatment, at baseline and at 6-month follow-up using interpretative phenomenological analysis.

Results: The findings demonstrate an effortful process of adjustment, including recognising and accepting a changed self, fostering control beliefs over the course of the illness and physical sequelae, searching for meaning, developing illness coherence and moving away from self-blame.

Conclusions: This study is the first to utilise a longitudinal qualitative design in oesophageal cancer, and provides an understanding of post-treatment adjustment over time for this clinical population through which to inform clinical practice and service development.  相似文献   

643.
Distortions in sensory experiences that precede a migraine attack have been extensively documented, the most well-known being the visual aura. Distortions in the experience of other senses are also reported as part of an aura, albeit less frequently, together with changes in the perception or ownership of the body or body parts. There are many examples of differences in aspects of visual perception between migraine and control groups, between attacks, but not as much on unusual experiences involving other senses, the sense of the body or the experience of the environment. Seventy-seven migraine (33 with aura) and 74 control participants took part. Anomalous perceptions were experienced by both migraine and control groups, but more with migraine experienced them and rated them as more distressing, intrusive and frequent. Associations with reports of visual triggers of migraine and visual discomfort are presented. This study is the first to show relationships between these factors.  相似文献   
644.
645.
Objectives: Given the lack of validated measures assessing illness perceptions in families, the aim of our study was the development and psychometric testing of an adapted version of the Illness Perceptions Questionnaire-Revised (IPQ-R) allowing for Common Sense Model-based dyadic assessment of adolescents’ and caregivers’ perceptions of a chronic illness in adolescence.

Methods: Using a cross-sectional survey design, factor structure, reliability and validity of the adapted measure You-IPQ-R were tested in a sample of adolescents with asthma (N?=?155) and their primary caregivers (N?=?132). Analysis included a dyadic methodology (dyadic confirmatory factor analyses) and examination of the suitability of the measure for different age groups.

Results: Both the adolescent and the caregiver versions of the You-IPQ-R revealed good overall validity and reliability. For all Common Sense Model dimensions except for timeline cyclical in the caregiver version, unidimensional scales aligning with the original IPQ-R structure could be confirmed. Age-specific analyses revealed good to excellent measurement properties in adolescents aged 14 years or older, but considerably poorer indices in younger adolescents.

Conclusion: The dyadically validated You-IPQ-R will enable researchers and clinicians to compare illness perceptions in adolescent–caregiver dyads and to assess the effects of family illness perceptions’ congruence upon medical, psychosocial and behavioural outcomes.  相似文献   

646.
The Maryland Resource for the Behavioral Utilization of the Reinforcement of Negative Stimuli (MRBURNS) is a novel behavioral task designed to measure individual differences in negative reinforcement-based risk taking propensity. Performance on the MRBURNS has been linked with alcohol-related problems and negative reinforcement-based drinking motives, as well as symptoms of anxiety and depression; however, it is unclear if performance on the task represents a stable measure of negative reinforcement-based risk taking over time. As such, the current study aimed to examine the test–retest reliability of the MRBURNS over a period of one year. Results indicate that the correlation between year 1 and year 2 risk behavior (average number of pumps) on the MRBURNS was .43 across all trials. With the one year test–retest reliability of the MRBURNS established, the MRBURNS may be a useful approach to measuring the relative contribution of negative reinforcement-based risk taking in the development of risky behaviors over time, and may be used to monitor the effects of novel interventions that aim to reduce negative reinforcement based risk taking in the real world.  相似文献   
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