Attributed influence: The importance of observing change

The presence of a target's unexpected change in behavior following an influence attempt was hypothesized to be a critical variable for attributing influence to a particular agent. Observers read a brief story in which an agent's intervention was followed by the target's compliance, noncompliance, or countercompliance to the request. The results indicated that influence was attributed to the agent in the conditions demonstrating change, i.e., compliance and countercompliance, regardless of the direction of that change. Additional findings indicated that influence attributed to an agent decreased if the target delayed final compliance with the intervention.     

Diagnostic accuracy of the Millon test computer reports for bipolar affective disorder

The diagnostic accuracy of the Millon Clinical Multiaxial Inventory (MCMI) computer reports was assessed for the sample of 48 patients reliably identified as having bipolar affective disorder. Only 13 of the 48 reports were accurate in classifying the patients as having bipolar affective disorder, and this was significantly (p < .01) less than 50% of the cases. The diagnostic accuracy clearly left much to be desired. Additional research is needed to assess the validity of MCMI diagnostic suggestions for other patient groups.     

随机化临床试验在外科领域的困惑与出路

临床科研方法一直受到流行病学理论的影响。在临床流行病学提出随机化临床试验（ＲＣＴ）的理论之后，许多临床领域的比较研究如筛选诊断技术、评价治疗效果和估计预后等，均广泛采用了这一科学的论证方法。但ＲＣＴ在外科领域却走入了困境。本文综合分析了在外科领域开展ＲＣＴ的困惑、外科临床研究方法的现状，并提出了提高外科临床研究科学性的可行途径。     

Eating disorder NOS (EDNOS): an example of the troublesome "not otherwise specified" (NOS) category in DSM-IV

The “Not Otherwise Specified” (NOS) category within DSM-IV is designed for disorders of clinical severity that are not specified within broad diagnostic classes. “NOS” diagnoses are intended to be residual categories and they tend to be neglected by researchers. This can be inappropriate. The problems associated with certain NOS diagnoses are well illustrated by “Eating Disorder NOS” (sometimes termed EDNOS), which is the most common category of eating disorder encountered in routine clinical practice yet it has barely been studied. Indeed, there has been no research on its treatment. Interim and longer-term conceptual and practical solutions to the anomalous status of eating disorder NOS are proposed including the creation of a new diagnosis termed “mixed eating disorder”. Several of these solutions are of relevance to NOS categories in general. All the solutions should fulfil criteria for clinical utility.     

The CIOMS view on the use of placebo in clinical trials

Based on worldwide consultations with experts in science and ethics the revised CIOMS 2002 International Ethical Guidelines for Biomedical Research Involving Human Subjects provide guidance on when the use of placebo as a comparator in clinical research is ethically acceptable. The article reviews the main points of the CIOMS Guidelines and commentaries including the use of placebo in situations where the best current method is available and the relation of placebo to established effective intervention. It discusses the use of placebo in externally sponsored research in low-resource countries and requirements for informed consent related to placebo studies. An earlier version of this paper was presented at an international conference, “Placebo: Its Action and Place in Health Research Today,” held in Warsaw, Poland on 12–13 April, 2003.     

The Golombok Rust Inventory of Sexual Satisfaction (GRISS): predictive validity and construct validity in a Dutch population

The discriminant and predictive validity of the Dutch translation of the Golombok Rust Inventory of Sexual Satisfaction (GRISS; Rust and Golombok, 1985, Rust and Golombok, 1986a, Rust and Golombok, 1986b; Ter Kuile et al., (1993); Ter Kuile et al., accepted for publication) was examined in independent samples comprising sexological (357 males and 380 females) and gynaecological outpatients (156 males and 209 females). Prediction of the presence of sexual complaints with the GRISS differed in these samples. The best performance was found in the male sexology sample in which sensitivity and specificity, as well as the predictive values both positive and negative were satisfactory. The predictive characteristics in the other three samples were found to be less satisfactory and were confounded with sample characteristics concerning the presence or absence of individual sexual problems. The availability of the other partners' GRISS scores enhanced the GRISS' predictive capacities for males and females in these samples. In 320 female and 300 male sexology patients and their partners, the convergent and divergent construct validity of the GRISS scales was investigated using other instruments measuring psychological distress, marital, sexual and general life maladjustment, personality traits of psychoticism, extraversion and neuroticism and social desirability. No correlations of the GRISS with social desirability were found. GRISS subscales were found to represent relatively independent constructs. These findings were confirmed by higher-order factor analyses of subscale scores of males and females.     

Feature selection and classification: A developmental study

Two hundred and thirteen children between the ages of 4 and 16 sorted 30 complex objects freely into groups. These were either schematic faces, schematic imaginary animals, or histoform patterns and were constructed from 9 independently and continuously varying features, each with 10 levels. The three sets were equivalent in terms of underlying numerical structure. A new method of analysis of the groups formed yielded the following direct measures of subjective organization in the sorting of each child: the number of features used in sorting, the accuracy of sorting, and the number of independent dimensions of classification. Both the material and the analysis of sorting were devised on the assumption that only some of the component features of complex objects are used for classification, while others are ignored. Sorting performance differed markedly both with age and with different types of material. The improvement in sorting ability with age, except for the youngest children, could be attributed to an increase in the number of features used rather than an improvement in the accuracy of use. In contrast, the poor sorting of histoform patterns as opposed to faces and animals was due to a low level of sorting accuracy. The basic results on the development of classification confirmed previous studies, and hence suggest that it is valid to consider feature selection as a basic component of classification.