Functional connectivity associated with five different categories of Autonomous Sensory Meridian Response (ASMR) triggers

Autonomous sensory meridian response (ASMR) is a sensory-emotional phenomenon in which specific sensory stimuli (“ASMR triggers”) reliably elicit feelings of relaxation and tingling sensations on the head, neck, and shoulders. However, there are individual differences in which stimuli elicit ASMR and in the intensity of these responses. In the current research, we used resting-state fMRI to examine the functional connectivity associated with these differences. Fifteen individuals with self-reported ASMR completed the ASMR Checklist, which measures sensitivity to different ASMR triggers, and a resting-state fMRI scan. Checklist scores were entered as covariates to determine whether the functional connectivity of eight resting-state networks differed as a function of participants’ sensitivity to five categories of triggers. The results indicated unique patterns of functional connectivity associated with sensitivity to each ASMR trigger category. Sensitivity to two trigger categories was positively correlated with the dorsal attention network, suggesting that ASMR may involve atypical attentional processing.     

The effect of learner-adapted practice schedule and task similarity on motivation and motor learning in older adults

The purpose of the present study was to investigate the effect of learner-adapted practice schedule and task similarity on intrinsic motivation and motor learning in older adults. For this purpose, 60 right-handed older adults were randomly divided into six groups of blocked-similar, learner-adapted-similar, random-similar, blocked-dissimilar, learner-adapted-dissimilar, and random-dissimilar. Sequential timing was used as the task, and the intrinsic motivation questionnaire was used for measuring individuals' motivation. The learner-adapted practice was included performing the task in a combination of blocked, serial, and random orders according to error number in each block. The results showed that the learner-adapted practice significantly outperformed than other practice schedules in motivation and motor learning measures in similar and dissimilar conditions. Also, the random schedule resulted in superior performance than the blocked schedule in similar and dissimilar conditions. These findings were discussed according to the challenge point framework.     

Reducing Proactive Interference in Motor Tasks

Abstract

Changing automatized movement patterns often leads to initial performance decrements caused by proactive interference. In this study, we scrutinized whether proactive interference could be reduced by inhibiting the to-be-changed movement pattern by means of a physical movement constraint and verbal inhibition instructions, and whether any of the two interventions may be superior. Skilled typists typed short texts as fast and accurately as possible on a regular QWERTZ keyboard. After baseline measures, a new rule prohibiting the use of the left index finger was introduced. Subsequently, participants took part in either a verbal instruction or an additional motor restriction intervention phase. Results revealed that the original rule change was successful in inducing proactive interference in skilled typists. Most importantly, the two interventions similarly reduced proactive interference both immediately following the rule change and after ten practice sessions. We conclude that reducing proactive interference by means of physical motor restrictions and verbal instructions may be equally effective.     

Verbal and practical intelligence in general anxiety,obsessive compulsive and major depression disorders

IntroductionPrevious researches have shown that anxiety symptoms are negatively associated with measures of intelligence. However, recent findings indicate possible positive relationships between Generalized Anxiety Disorders (GAD) and intelligence. Also, Obsessive Compulsive Disorder (OCD) is associated with a moderate degree of underperformance on cognitive tests, including deficient processing. There are inconsistent results to present the relationship between Major Depression Disorder (MDD) and IQ. The present study has three main aims. The first aim of this study is to investigate the difference between IQ in individuals with GAD, OCD and major depressive disorder, and normal group. The second purpose is to perform a comparative study between the GAD, OCD and MDD groups on verbal and non-verbal intelligence. The third aim of this study is to examine the relationships between GAD, OCD and MDD as well as their underlying cognitive processes, including worry, rumination, and post-event processing, with verbal and non-verbal intelligence.ObjectiveThe present study is performed on four groups of participants including those with GAD, OCD, MDD and Healthy Volunteer (HV) group consisting of individuals without psychiatric disorders.MethodThe number of 50 healthy volunteers as the control group, 45 patients with GAD, 20 patients with OCD and 25 patients with MDD (n = 140) were selected as the case-referent groups. The present study was a cross-sectional type and the research was performed based on the causal-comparative method. Verbal and non-verbal intelligence was measured with the Wechsler Adult Intelligence Scale-3rd edition (WAIS-III). Rumination and post-event processing were measured by PSWQ, RRS-BR, and PEPQ, respectively.ResultsThe results indicate that Verbal Intelligence and Verbal Comprehension Index in GAD patients have significant differences in comparison to the OCD, MDD and control groups. While, the value of the Working Memory Index (WMI) in the normal group is higher than the value of the same index in the GAD, OCD and MDD groups. Also, the values of the Processing Speed Index (PSI) in normal and GAD groups are higher than the OCD and MDD groups. The worry, rumination, and post-event processing in patients with GAD are positively correlated with general and verbal intelligence. But, verbal and non-verbal intelligence had a negative correlation with worry, rumination and post-event processing in healthy volunteers.ConclusionInvestigation of the possible connections between intelligence and the cognitive processes underlying emotional disorders can provide therapeutic strategies for smart individuals who are at risk for GAD.     

Familiarity and categorization processes in memory search

A fundamental distinction in tasks of memory search is whether items receive varied mappings (targets and distractors switch roles across trials) or consistent mappings (targets and distractors never switch roles). The type of mapping often produces markedly different performance patterns, but formal memory-based models that account quantitatively for detailed aspects of the results have not yet been developed and evaluated. Experiments were conducted to test a modern exemplar-retrieval model on its ability to account for memory-search performance involving a wide range of memory-set sizes in both varied-mapping (VM) and consistent-mapping (CM) probe-recognition tasks. The model formalized the idea that both familiarity-based and categorization-based processes operate. The model was required to fit detailed response-time (RT) distributions of individual, highly practiced subjects. A key manipulation involved the repetition of negative probes across trials. This manipulation produced a dramatic dissociation: False-alarm rates increased and correct-rejection RTs got longer in VM, but not in CM. The qualitative pattern of results and modeling analyses provided evidence for a strong form of categorization-based processing in CM, in which observers made use of the membership of negative probes in the “new” category to make old–new recognition decisions.     

Exploring inhibitory deficits in female premutation carriers of fragile X syndrome: Through eye movements

There is evidence which demonstrates that a subset of males with a premutation CGG repeat expansion (between 55 and 200 repeats) of the fragile X mental retardation 1 gene exhibit subtle deficits of executive function that progressively deteriorate with increasing age and CGG repeat length. However, it remains unclear whether similar deficits, which may indicate the onset of more severe degeneration, are evident in female PM-carriers. In the present study we explore whether female PM-carriers exhibit deficits of executive function which parallel those of male PM-carriers. Fourteen female fragile X premutation carriers without fragile X-associated tremor/ataxia syndrome and fourteen age, sex, and IQ matched controls underwent ocular motor and neuropsychological tests of select executive processes, specifically of response inhibition and working memory. Group comparisons revealed poorer inhibitory control for female premutation carriers on ocular motor tasks, in addition to demonstrating some difficulties in behaviour self-regulation, when compared to controls. A negative correlation between CGG repeat length and antisaccade error rates for premutation carriers was also found. Our preliminary findings indicate that impaired inhibitory control may represent a phenotype characteristic which may be a sensitive risk biomarker within this female fragile X premutation population.