Issues Involving Informed Consent for Research Participants with Alzheimer’s Disease

Alzheimer’s disease is the most common form of dementia which is estimated to impact 350,000 people over 65 years of age in Canada. The lack of effective treatment and the growing number of people who are expected to be diagnosed with Alzheimer’s disease in the near future are compelling reasons why continued research is in this area is necessary. With additional research, there needs to be greater recognition of the complexity of seeking ongoing informed consent from those with Alzheimer’s disease. This complexity is because the impairment of memory and cognitive ability does not diminish in a linear manner, but rather fluctuates between periods of impairment and relatively normal cognitive lucidness. There is limited discussion in the guidelines of those progressing from early stages of Alzheimer’s disease who have intermittent cognitive function. Guidelines to research and Research Ethics Boards require further development to facilitate researcher including those with Alzheimer’s disease while protecting this growing pool of potential participants.     

A code of ethics for the life sciences

The activities of the life sciences are essential to provide solutions for the future, for both individuals and society. Society has demanded growing accountability from the scientific community as implications of life science research rise in influence and there are concerns about the credibility, integrity and motives of science. While the scientific community has responded to concerns about its integrity in part by initiating training in research integrity and the responsible conduct of research, this approach is minimal. The scientific community justifies itself by appealing to the ethos of science, claiming academic freedom, self-direction, and self-regulation, but no comprehensive codification of this foundational ethos has been forthcoming. A review of the professional norms of science and a prototype code of ethics for the life sciences provide a framework to spur discussions within the scientific community to define scientific professionalism. A formalization of implicit principles can provide guidance for recognizing divergence from the norms, place these norms within a context that would enhance education of trainees, and provide a framework for discussing externally and internally applied pressures that are influencing the practice of science. The prototype code articulates the goal for life sciences research and the responsibilities associated with the freedom of exploration, the principles for the practice of science, and the virtues of the scientists themselves. The time is ripe for scientific communities to reinvigorate professionalism and define the basis of their social contract. Codifying the basis of the social contract between science and society will sustain public trust in the scientific enterprise.     

Croatia founded a national body for ethics in science

The Committee for Ethics in Science and Higher Education (CESHE) was created in Croatia as a national body appointed by the Parliament. Thus Croatia became one of a handful of countries with national means of responding to allegations of scientific misconduct. The Committee’s duties, with the help of the Ethics Code, include promotion of ethical norms and values in science and higher education. The CESHE will work on cases of possible research misconduct and alleged disregard for the ethical norms associated with research.     

Differences in preschoolers’ and adults’ use of generics about novel animals and artifacts: A window onto a conceptual divide

Children and adults commonly produce more generic noun phrases (e.g., birds fly) about animals than artifacts. This may reflect differences in participants’ generic knowledge about specific animals/artifacts (e.g., dogs/chairs), or it may reflect a more general distinction. To test this, the current experiments asked adults and preschoolers to generate properties about novel animals and artifacts (Experiment 1: real animals/artifacts; Experiments 2 and 3: matched pairs of maximally similar, novel animals/artifacts). Data demonstrate that even without prior knowledge about these items, the likelihood of producing a generic is significantly greater for animals than artifacts. These results leave open the question of whether this pattern is the product of experience and learned associations or instead a set of early-developing theories about animals and artifacts.     

超越个体：组织公民行为跨层次研究

以往的研究认为组织公民行为是个人行为,并且大多数研究是在个体层次上展开的。事实上,由于组织中的个体嵌入在群体和组织中,组织公民行为会受到群体和组织等不同层次因素的影响。本文从层次问题入手,对国外文献深入系统研究的基础上,对组织公民行为的研究层次和研究模型进行梳理,以期明晰组织公民行为的层次研究现状,并在此基础上探讨中国本土化情境下开展组织公民行为跨层次研究的必要性和可行性。     

教改对教师工作生活质量影响的跨文化比较研究

本研究采用跨文化教育协作组(CCCRE)编制的访谈问卷,采用结构化访谈方式,通过跨文化教育研究协作对9个国家513名教师进行访谈调查。本文着重探讨了教改的种类、起因和角色特征对教师工作生活质量的影响。结果表明:1)教改类型对教师人际关系和职业发展的变化有显著影响2)教改起因对教师的时间利用和职业发展有显著影响,并在时间利用上显示出文化上的差异。3)我国教改在起因上表现出与总体趋同态势,但它们对教师的人际关系和职业发展的变化有更积极的影响。4)执行者是教师在教改中的主要角色,但这种角色对教师的工作生活质量没有显著影响。     

Speech and bimanual hand organization in adult stutterers and nonstutterers

A multivariate approach was used to investigate the relationship between speech fluency and bimanual handwriting in right-handed male stutterers and nonstutterers. Handedness was determined by the Harris Test of Lateral Dominance. Subjects were required to write the numbers 1 through 12 simultaneously, as quickly as possible. Speech measures were derived from the Stuttering Severity Instrument and from a reading passage. Stutterers performed more poorly than nonstutterers on all speech measures. There were no differences in bimanual handwriting performance for the dominant hand. However, stutterers performed more poorly than nonstutterers in nondominant handwriting. There were no relationships between speech measures and bimanual handwriting for stutterers or nonstutterers. Some stutterers performed better on the handwriting task than did some nonstutterers. It is suggested that disorganization in interhemispheric integration functions may be a more fundamental problem in stuttering than is incomplete cerebral dominance.     

The effect of context during word perception in schizophrenic patients

Hospitalized chronic and acute schizophrenics were compared with age- and social-status-matched controls on word perception tests to measure the effect of context on recognition thresholds. In Experiment 1 the method of J. Morton (1964, British Journal of Psychology, 55, 165-180) was adopted to see how related and unrelated contexts influenced word recognition thresholds when both context and stimulus word were presented visually. Experiment 2 was an auditory analog of Experiment 1 and in addition the chronic schizophrenics were selected on the basis of a presence or absence of auditory hallucinations. The influence of context on perceptual thresholds was quite normal in all schizophrenics. However, analysis of the incorrect responses elicited showed that some schizophrenic subjects do produce bizarre or irrelevant responses or perseveration to a greater extent than their controls. These results are explained in terms of automatic and strategic modes of information processing. The automatic processes responsible for the adjustment of perceptual thresholds operate normally in schizophrenics but response production which demands strategic selection and editing of responses is prone to malfunction which results in the observed deviations in the normal use of language.