Case report of stuttering acquired in association with phenytoin use for post-head-injury seizures

Previous research indicates that stuttering and deficits in motor performance may be associated with the use of phenytoin (Dilantin). The present report concerns a case of stuttering acquired in association with phenytoin use for post-head-injury seizures. The extent and nature of dysfluencies and the motor performance of speech and nonspeech muscle systems were evaluated over an extended period during which changes in anticonvulsant medication were made. Reductions in dysfluency levels and improved motor performance were observed following a medication change from phenytoin to carbamazepine. Performance on tests assessing nonmotor functions, such as memory and attention, was equivalent before and after the medication change. The apparent association between dysfluency levels, motor performance deficits, and phenytoin suggest that in the present case stuttering resulted in part from a general impairment in motor control.     

Children's identity matching and oddity: assessing control by specific and general sample-comparison relations.

After children in Experiments 1 and 2 learned identity matching or oddity, control by sample-comparison relations was assessed. Tests for generalized control displayed novel samples and two comparison stimuli, one identical to the sample. Specific relations were tested with identical or nonidentical sample-comparison stimuli from one set of stimuli and substitute comparisons from either the other training set or from a novel set. When tests displayed identical stimuli, patterns of comparison selection suggested control by generalized identity and oddity. However, selection patterns varied when stimuli were nonidentical and familiar or novel substitute comparisons were used. Therefore, control by specific relations is not a precondition for generalized identity and oddity. One set of training stimuli was used in Experiment 3, and generalized performances occurred again. Moreover, control by specific relations was shown by the oddity subjects and 2 of 6 identity subjects. Generalized and specific control may therefore exist simultaneously. In Experiment 4, selections were irregular on tests displaying substitute comparisons and samples and familiar comparison stimuli; this finding supported the relational account of specific sample-comparison control found in Experiment 3.     

SCIENCE AND THE FORTUNES OF NATURAL THEOLOGY: SOME HISTORICAL PERSPECTIVES

Abstract. The object is to examine strategies commonly used to heighten a sense of the sacred in nature. It is argued that moves designed to reinforce a concept of Providence have been the very ones to release new opportunities for secular readings. Several case studies reveal this fluidity across a sacred-secular divide. The irony whereby sacred readings of nature would graduate into the secular is also shown to operate in reverse as anti-providentialist strategies invited their own refutation. The analysis is used to support the claim that the sciences have put fewer constraints on religious belief than is generally assumed.     

Inner speech as a learned skill

Three experiments are reported which address the problem of defining a role for inner speech. Experiments 1 and 2 establish that inner speech is acquired by normally developing readers between the ages of 8 and 11, and that both slow and fast readers show a similar pattern of acquistition, but do so at a different rate from normal readers. We suggest that the development of inner speech accompanies a strategy of reading aloud “with expression”; and that it is a manifestation of the need to prestructure oral utterances. These will thus contain the lexical items visible on the page within an appropriate prosodic envelope. Both segmental and suprasegmental phonemes contribute to meaning of spoken and, by analogy, written language. Experiment 3 showed that children at this critical point in learning to read comprehended text better when certain prosodic features were made visible on the text. Prosodic restructureing may thus be an important skill acquired by young readers as they progress toward fluent, silent adult reading.     

Perception of symmetry in infancy: the salience of vertical symmetry and the perception of pattern wholes

Four experiments were conducted to assess converging aspects of 4-month-old infants' perception of symmetry in visual patterns. Experiments 1 and 2 manipulated the structure and orientation of comparable patterns in order to evaluate the specialty of vertical symmetry. Infants showed no preference among vertically symmetrical, vertically repeated, and obliquely symmetrical patterns, but they processed vertically symmetrical patterns more efficiently than either vertically repeated patterns or obliquely symmetrical patterns. Experiment 3 manipulated the spatial separation of pattern components in order to determine the ability of young infants to integrate and coalesce information in visual patterns that is distributed in space. Infants processed vertically symmetrical patterns whose components were contiguous or nearly contiguous about the vertical axis (0 to 2.5 degrees separations) more efficiently than discontiguous patterns (5 and 10 degrees separations). Thus, extreme spatial separation about the vertical meridian caused infants to lose the advantage for vertical symmetry, and by inference their holistic perception of the visual pattern. Experiment 4 manipulated the organization of individual components of a vertical pattern in order to examine further infants' sensitivity to perceptual organization and synthesis of pattern form. Infants discriminated vertically symmetrical patterns from asymmetrical patterns with a vertical organization, thereby demonstrating sensitivity to the symmetrical organization of the pattern above their perception of components in the pattern. The results of these four experiments together corroborate and extend previous findings that vertical symmetry has a special status in early perceptual development and that infants can perceive pattern wholes.     

Response-outcome contingency: Behavioral and judgmental effects of appetitive and aversive outcomes with college students

In two experiments, positive, negative, and zero response-outcome contingencies were responded to and rated by college students under a free-operant procedure. In Experiment 1, outcomes were either neutral or were associated with point gain. In Experiment 2, subjects were administered different outcome treatments: neutral outcomes, outcomes associated with money gain, or outcomes associated with money loss. In both experiments, subjects' judgments of response-outcome contingency and their operant responses were each strong linear functions of ΔP, the difference between the probability of an outcome given a response and the probability of an outcome given no response. Appetitive and aversive outcomes produced opposite and symmetrical response patterns. In Experiment 1, no differences in ratings occurred with neutral or appetitive outcomes; however, in Experiment 2, more potent appetitve outcomes led to somewhat more extreme ratings than either neutral or aversive outcomes. Increasing outcome probability produced only a slight bias in ratings of noncontingent problems in Experiment 1 and no bias in Experiment 2. Contrary to predictions derived from an analysis of superstitious behavior, increasing outcome probability in noncontingent problems decreased operant responding when outcomes were appetitive and increased operant responding when outcomes were aversive. Trend analyses revealed that Δ P was superior to several other metrics in predicting subjects' estimates of contingency and the behavioral effects of contingency. Operant responding was in closer accord with matching predictions than with maximizing predictions.     

Asymmetrical effects of Pavlovian excitatory and inhibitory aversive transfer on Pavlovian appetitive responding and acquisition

Predictions of a theory of Pavlovian motivational transfer, which incorporates principles of both the theory of reciprocal inhibition and the Rescorla-Wagner model, were tested in several Pavlovian aversive to Pavlovian appetitive transfer tasks. As predicted, the presence of a signal for an aversive event, conditioned stimulus (AV CS+), reliably suppressed performance of appetitive conditioned responses (CRs) whether imposed during acquisition or on independently established responding. Acquisition of appetitive responding to a novel CS reinforced in compound with an AV CS+, however, was enhanced (“superconditioning”). This observation suggests that the effects of a discrepancy between expectation and actual outcome on a conditioning trial are influenced by the affective value of both the expectation and the reinforcer. These transfer effects were not symmetrical for an inhibitory aversive stimulus (AV CS?). An AV CS? did not enhance appetitive responding compared to a random control condition, nor did the AV CS? reduce (i.e., block) appetitive conditioning to a novel CS when appetitive reinforcement occurred in the presence of the AV CS?. Comparison of the two shock-exposed conditions with a naive control condition suggests that previous results that were apparently consistent with inhibitory aversive enhancement and blocking of appetitive conditioning may have been due to aversive context conditioning.     

Cognitive analysis of a case of pure dysgraphia

An Italian patient with a pure dysgraphia who incorrectly spelled words and nonwords is described. The spelling errors made by the patient were not affected by lexical factors (e.g., frequency, form class) and were qualitatively the same for words and nonwords. The pattern of writing performance is discussed in relation to current models of writing and, specifically, in relation to the role of the Output Grapheme Buffer and Phoneme-Grapheme Conversion in writing.