Type D personality,but not Type A behavior pattern,is associated with coronary plaque vulnerability

Personality traits are associated with major adverse coronary events (MACE) in patients with coronary artery disease (CAD). However, the link between personality traits and intravascular morphology in CAD patients is poorly understood. This study investigated the relationship between personality traits, specifically Type A behavior pattern and Type D personality, and plaque vulnerability. After adjustment for demographic and clinical factors, multivariable regression analysis showed no association between Type A and optical coherence tomography indices. However, Type D personality was independently associated with lipid plaque, thin cap fibroatheroma (TCFA), and fibrous cap thickness. More specifically, negative affectivity of Type D was related to lipid plaque, TCFA and fibrous cap thickness, and social inhibition was associated with plaque rupture. Our results show that Type D personality was associated with plaque vulnerability, independent of clinical factors. Measurement of negative affectivity and social inhibition will increase our understanding of the progressive phase of the plaque vulnerability, which can contribute to the early identification of high risk patients and reduce the incidence of MACE.     

免除伦理审查制度及其应用实践建议

2023年发布的《涉及人的生命科学和医学研究伦理审查办法》（以下简称《办法》）首次设立了免除伦理审查制度。该制度设计旨在提升伦理审查效率,但也面临一系列的应用实践挑战。从澄清免除伦理审查的概念入手,简要分析免除伦理审查制度设计的初衷和必要性,同时,以美国为例,介绍了免除伦理审查制度的国际进展以及既往实践的经验教训。最后,针对《办法》提出的免除伦理审查相关要求的重点和难点进行了探讨,并就免除伦理审查的决定主体、标准操作程序,以及免除伦理审查的研究的跟踪审查等应用实践细节提出初步建议。

     

The Ability of Face Viewpoint Transformation Remains Immature at Age of 12: Evidence from Recognition of Faces with Different Familiarity in Children

Children are immature in face recognition, particularly in face configural decoding. This study examines the developmental difference of face recognition in another mechanism: viewpoint transformation processing. Adults and sixth‐grade children were instructed to match a series of one‐tone black face silhouettes to their corresponding front‐view faces. This task involves sophisticated calculation in pictorial information, precise viewpoint transformation, and most probably a 3‐D face representation. The results showed that although the performances were well above chance level in the recognition of familiar faces, for children, they were at chance level in the recognition of unfamiliar faces. The results indicate that children, at least to the age of about 12 years, are still immature in the processing of face viewpoint transformation compared to adults.     

Free recall and retrieval speed of categorized items by kindergarten children

Kindergarten Ss were presented with 16 pictorial items in four category sets or a partially random ordem with one item from each category composing the four presentation sets. The pictures were presented either on conceptually related background pictures or on white backgrounds. The categorically grouped presentation facilitated free recall performance, both in terms of number of items recalled and the speed with which the items were recalled, and increased the amount of clustering in recall. Categorical clustering in recall was associated with shorter within- than between-category intervals and for those Ss who recalled items from each of four categories successively, the over-all temporal pattern in recall closely approximated that found with adults. No background effects were found.     

Satisfiability Decay along Conjunctions of Pseudo-Random Clauses

k-SAT is a fundamental constraint satisfaction problem. It involvesS(m), the satisfaction set of the conjunction of m clauses,each clause a disjunction of k literals. The problem has manytheoretical, algorithmic and practical aspects. When the clauses are chosen at random it is anticipated (butnot fully proven) that, as the density parameter m/n (n thenumber of variables) grows, the transition of S(m) to beingempty, is abrupt: It has a "sharp threshold", with probability1 – o(1). In this article we replace the random ensemble analysis by apseudo-random one: Derive the decay rule for individual sequencesof clauses, subject to combinatorial conditions, which in turnhold with probability 1 – o(1). This is carried out under the big relaxation that k is not constantbut k = log n , or even r log log n . Then the decay of S isslow, "near-perfect" (like a radioactive decay), which entailssharp thresholds for the transition-time of S below any givenlevel, down to S = .     

Categorization of two-dimensional and three-dimensional stimuli by 18-month-old infants

In two experiments, 18-month-old infants’ categorization of 3D replicas and 2D photographs of the same animals and vehicles were compared to explore infants’ flexibility in categorization across different object representations. Using a sequential touching procedure, infants completed one superordinate and two basic-level categorization tasks with 3D replicas, 2D cut out photographs, or 2D images on photo cubes (“2D cubes”). For superordinate sets, 3D replicas elicited longer mean run lengths than 2D cut outs, and 3D replicas elicited equivalent mean run lengths as 2D cubes. For basic-level sets, infants categorized high-contrast animal sets when presented with 3D replicas, but they failed to categorize any of the 2D photograph sets. Categorization processes appear to differ for 3D and 2D stimuli, and infants’ discovery of object properties over time while manipulating objects may facilitate categorization, as least at the superordinate level. These findings are discussed in the context of infants’ representation abilities and the integration of perception and action.     

How Do Children Restrict Their Linguistic Generalizations? An (Un‐)Grammaticality Judgment Study

A paradox at the heart of language acquisition research is that, to achieve adult‐like competence, children must acquire the ability to generalize verbs into non‐attested structures, while avoiding utterances that are deemed ungrammatical by native speakers. For example, children must learn that, to denote the reversal of an action, un‐ can be added to many verbs, but not all (e.g., roll/unroll; close/*unclose). This study compared theoretical accounts of how this is done. Children aged 5–6 (N = 18), 9–10 (N = 18), and adults (N = 18) rated the acceptability of un‐ prefixed forms of 48 verbs (and, as a control, bare forms). Across verbs, a negative correlation was observed between the acceptability of ungrammatical un‐ prefixed forms (e.g., *unclose) and the frequency of (a) the bare form and (b) alternative forms (e.g., open), supporting the entrenchment and pre‐emption hypotheses, respectively. Independent ratings of the extent to which verbs instantiate the semantic properties characteristic of a hypothesized semantic cryptotype for un‐ prefixation were a significant positive predictor of acceptability, for all age groups. The relative importance of each factor differed for attested and unattested un‐ forms and also varied with age. The findings are interpreted in the context of a new hybrid account designed to incorporate the three factors of entrenchment, pre‐emption, and verb semantics.