到底路有多长--对干细胞移植治疗研究的一点思考

目前干细胞研究的争论主要集中于干细胞研究的过程和方式,诸如干细胞来源以及被提取干细胞的胚胎的权利与地位等伦理问题是争论的焦点所在,而对于研究的最终目的是治病而非克隆人则少有争议.然而在伦理问题等争论相对较小的干细胞应用研究领域,就应用于人的技术层面而言还有很多问题有待解决.安全性(safety)和有效性(efficacy)原则是目前公认的干细胞临床应用研究的基准.干细胞移植治疗最终应用于临床可能还有相当一段路程要走,无论是研究者还是伦理学家以及社会舆论和普通百姓在其中都应当并可以发挥积极的作用.     

Judgments of mean speed and predictions of route choice

How are driving speeds integrated when speeds vary along a route? In a first study, we examined heuristic processes used in judgments of mean speed when the mean speeds on parts of the trip varied. The judgments deviated systematically from objective mean speeds because the distances driven at different speeds were given more weight than travel time spent on the different distances. The second study showed that when there was a 10–15 min pause during a travel the effect on the mean speed decrease was underestimated for driving speeds of 90 km/h and higher. In the third study, the objective mean speeds and the subjective biased mean speed judgments were used to predict choices between routes with different speed limits. The results showed that subjective judgments predicted decisions to maximize mean speed significantly better than objective mean speeds. Finally, some applied and basic research implications of the results were discussed.     

Rethinking safety behaviors in insomnia: examining the perceived utility of sleep-related safety behaviors

Harvey's cognitive model of insomnia (2002a) proposes that sleep-related safety behaviors play a central role in the maintenance of insomnia because such maladaptive coping strategies are thought to reinforce threat-based appraisals of the likelihood and consequences of poor sleep. Research to date has assessed the frequency of safety behavior use in those with insomnia only; however, in addition to the frequency of occurrence, the function of safety behaviors (i.e., a belief that they will prevent a feared outcome from occurring), may be an important consideration. The purpose of this study was to examine sleep-related safety behaviors based on an expanded theoretical understanding of such behaviors across psychological disorders; that is, by examining both their frequency and perceived utility. Undergraduate students (N = 376) completed an online survey about their sleep, mood, and use of sleep-related safety behaviors. Insomnia severity was associated with a greater perceived need to use safety behaviors (i.e., utility) but not with frequency of safety behavior use. Higher perceived utility of safety behaviors was also associated with unhelpful beliefs about sleep, fear and avoidance of fatigue, and both general and sleep-specific helplessness. These results suggest that these behaviors and the associated underlying maladaptive beliefs may be important targets in cognitive behavioral therapy for insomnia. The current study extends the existing literature and refines the concept of safety behaviors in insomnia to include both the function and frequency of these behaviors.     

The effects of prompting and reinforcement on safe behavior of bicycle and motorcycle riders

A reversal design was used to evaluate the effects of vocal and written prompts as well as reinforcement on safe behavior (dismounting and walking bicycles or motorcycles on a sidewalk) on a university campus. Results indicated that an intervention that consisted of vocal and written prompts and reinforcement delivered by security guards was effective at increasing safe behavior exhibited by bicycle and motorcycle riders. No differences were observed between vehicle type or gender with regard to engagement in safe behavior.     

The effects of a rectangular rapid-flashing beacon on vehicle speed

In 2008, nearly 31% of vehicle fatalities were related to failure to adhere to safe vehicle speeds (National Highway Traffic Safety Administration [NHTSA], 2009). The current study evaluated the effect of a rectangular rapid-flashing beacon (RRFB) triggered by excessive speed on vehicle speed using a combined alternating treatments and reversal design. The percentage of vehicles traveling above 41 mph (66 km per hour) decreased by 20%, and speed distributions showed a shift toward lower speeds during the RRFB condition.     

Right‐wing authoritarianism,Big Five and perceived threat to safety

Using structural equations modelling, we performed a secondary analysis of the data collected by the Italian Observatory of the North West (Italian national sample, N = 976) to investigate the direct, mediated and moderated relations connecting the Big Five personality factors and perceived personal and societal threat to safety with right‐wing authoritarianism (RWA). Openness, Conscientiousness and perceived societal threat to safety exerted additive effects on RWA; the relation between Openness and RWA was partially mediated by societal threat to safety and that between societal threat to safety and RWA was moderated by Openness. Limitations and possible developments of this research are discussed. Copyright © 2009 John Wiley & Sons, Ltd.     

道德领导与员工建言：一个调节-中介模型的构建与检验

近年来, 研究者就如何激发员工公开讲出自己的观点、意见和问题进行了大量的探索。其中, 道德领导对员工建言的效应受到了越来越多研究的关注。在以往研究的基础上, 本研究构建了一个调节-中介模型以探讨道德领导影响员工建言的中介心理机制及其边界条件。根据社会交换理论和社会信息加工理论, 本文分别提出两种不同的中介变量-- 责任知觉和心理安全感-- 来解释道德领导与员工建言之间的关系。在此基础上, 本研究进一步假设权力距离会正向调节变量之间的间接关系。通过对某一零售企业239名员工的两阶段调查, 我们对以上研究假设进行了检验, 结果总体上支持了本研究的理论预期。本研究的发现有利于我们了解道德领导影响建言行为的心理机制, 指导管理者采取有针对性的措施, 以期有效地管理企业中的员工建言行为。     

安全动机在安全绩效模型中的作用：自我决定理论的视角

在日常工作中, 安全动机是员工保持安全行为的重要决定因素。安全动机对安全绩效的影响虽然已引起研究者的关注, 但相关的实证研究缺少清晰的理论界定和有效的测量工具。本项目拟在安全绩效模型的基础上, 借鉴自我决定理论对动机的分类, 将安全动机的类型进行扩展, 并在多层次模型中探讨安全动机在变革型领导、个体特征和安全绩效之间的中介作用, 以及在中国管理背景下可能存在的边界条件。研究将结合访谈、问卷和情境实验等方法对上述变量间关系进行相关和因果关系的探讨。本项目将自我决定理论与安全绩效模型相结合, 可以为安全研究的动机理论发展做出贡献; 研究结果亦可为安全管理实践提供评价工具和有效指导。     

心理距离与后果严重性对人身安全决策的影响

已有研究发现决策者在为自己与不同他人决策时,其风险偏好存在差异。但是当对后果严重性不同的事件进行决策时,上述结果也并不总是如此。为了探究在人身安全情境中决策者面对后果严重程度不同的任务时,为自己和为他人决策时风险偏好的差异,实验一采用人际亲密度和决策所带来消极结果的严重程度分别操纵心理距离与后果严重性,结果发现决策者在后果严重任务中的决策比后果不严重任务更保守,为自己和为陌生人决策均比为最好朋友决策更冒险。这可能是由于决策者知觉到的决策责任不同所致。因此在实验一的基础上实验二引入决策责任这一变量,考察其在心理距离对风险决策影响中的作用,研究结果证明了我们的假设。