Neuropsychological Sequelae of Non-Central Nervous System Cancer and Cancer Therapy

Cancer patients report numerous adverse symptoms associated with their disease and treatment including cognitive dysfunction, fatigue, and affective distress. Cognitive dysfunction is ubiquitous in patients with primary central nervous system (CNS) cancer and recent evidence has documented similar deficits in patients with non-CNS cancer as well. Both the cancer itself and treatments including chemotherapy, biological response modifiers, and hormonal therapies have been demonstrated to adversely impact cognitive and neurobehavioral function. Neuroimaging and neurophysiological investigations have likewise revealed alterations in brain function that are helping to account for the nature of these cognitive disorders. Similarly, preclinical animal research is assisting to identify the pathophysiological mechanisms that underlie treatment-related neurotoxicities. The coalescence of multidisciplinary clinical and research efforts hold promise for the development of interventions that may offer neuroprotection in addition to currently available symptomatic therapies and cognitive rehabilitation techniques.     

A Comparison of Quality of Life Variables for Students with Emotional and Behavioral Disorders and Students Without Disabilities

The importance of quality of life has been increasingly recognized in the field of special education. To date, however, there are no studies focusing exclusively on students with emotional and behavioral disorders (EBD). This study examined quality of life differences between students with EBD and their nondisabled peers in four domains: (a) General quality of life; (b) Self; (c) Relationships; and (d) Environment. Additional analyses compared parent and adolescent ratings. Results indicated adolescents with EBD were significantly more dissatisfied with their quality of life in all domains than their non-EBD peers. No significant within group differences were found for gender or age; however, EBD students in self-contained schools rated self and environment significantly higher than their peers with EBD in public schools. Parents of adolescent with EBD rated their adolescent’s quality of life significantly lower than their adolescent did, while parents of non-EBD adolescents rated their adolescent’s quality of life as significantly higher than did their adolescents. This study has several implications for programming to improve the outcomes among this group of students.     

浅谈妇外科医生手术操作的四个层次

手术是处理妇科疾病的主要手段之一。本文从作者的经历和感触出发,就妇外科医师的成长过程中的共性规律进行总结。对于住院医师,熟悉解剖结构、练习基本操作是主要目标;对于主治医师,归纳手术套路、学会独立操作是主要任务;对于主任医师,承担常规工作的同时,条件和能力许可应有所创新。只有将手术从工作变为创作,将技术升华为艺术时,才能完成从“手术匠”到“大师”的飞跃。     

Expressive Electronic Journal Writing: Freedom of Communication for Survivors of Acquired Brain Injury

In addition to the impaired ability to effectively communicate, adults with acquired brain injury (ABI) also experience high incidences of depression, social isolation, and decreased quality of life. Expressive writing programs have been shown to be effective in alleviating these concomitant impairments in other populations including incarcerated inmates (Lane, Writing as a road to self-discovery, F & W, Cincinnati 1993). In addition, computer applications such as email have been suggested as an effective means of improving communication and social isolation in adults with brain injury (Sohlberg et al. [2003]. Brain Injury, 17(7), 609–629). This investigation examines the effects of on-line expressive journal writing on the communication, emotional status, social integration and quality of life of individuals with brain injury.     

The Happy-Productive Worker Thesis Revisited

Despite extensive research on the subject spanning over 70 years, uncertainty still remains as to whether happier workers are in fact more productive. This study combined longitudinal prospective and experience sampling methods to examine the relationship between happiness and self-reported productivity among Directors employed in the public and private sectors. Analyses at a trait level suggested happy people were more productive. Similarly, at the state level of analysis, people were more productive when they were happier. Among the happiness indicators examined (job satisfaction, quality of work life, life satisfaction, positive affect, and negative affect) positive affect was most strongly, but not exclusively, tied to productivity at both the state and trait levels. Discussion focuses on reconciling a long history of mixed findings regarding the happy-productive worker thesis.

Happiness in shrinking cities in Germany

After decades of urban growth, modern societies now face an increasing number of shrinking cities. What is the impact on the inhabitants of shrinkage of their city? Negative effects dominate in the public discourse, but does growth or shrinkage really matter for the livability in urban environment? In this paper, I take stock of the effect on subjective well-being in present day Germany. Overall satisfaction with life appears not to be lower in shrinking cities and satisfaction with several domains of life even higher. This is not because inhabitants are unaware of the situation of their city, since they appear to be more concerned about job-chances and crime.     

Quality of Life and General Health Perception in Women with Obesity

The purpose of this study was to determine the differences in general health status and quality of life between patients who present “non-normative eating behaviours” (namely, binge eating disorder, night eating syndrome, sweet /fat food cravings and continuous nibbling) and patients without these eating behaviour characteristics. A cohort of 168 women with obesity, all candidates to bariatric surgery, aged between 15 and 65 (M = 39.04; SD = 10.86), with a body mass index ranging between 30.37 and 80.65 (M = 48.79; SD = 8.37), was studied. Participants answered to a clinical interview, to SF-36 and to ORWELL-97, after their informed consent. Results suggest that women with obesity reporting binge eating disorder, night eating syndrome and continuous nibbling show poorer general health status and worst quality of life than those who do not present these “non-normative eating behaviours”. Moreover, the general health status and the quality of life of patients with sweet/fat food cravings do not differ from those who do not report this eating behaviour. Nevertheless, patients reporting the eating behaviours studied do not differ from the others regarding their body mass index.     

Self-efficacy and quality of life in adults who stutter

PurposeSelf-efficacy has emerged as a potential predictor of quality of life for adults who stutter. Research has focused primarily on the positive relationship self-efficacy has to treatment outcomes, but little is known about the relationship between self-efficacy and quality of life for adults who stutter. The purpose of this mixed- methods study is to determine the predictive value of self-efficacy and its relationship to quality of life for adults who stutter.MethodThe Self-Efficacy Scale for Adult Stutterers and the Overall Assessment of the Speaker’s Experience with Stuttering were administered to 39 adults who stutter, aged 18– 77. Percentage of syllables stuttered was calculated from a conversational speech sample as a measure of stuttered speech frequency. Qualitative interviews with semi-structured probes were conducted with 10 adults and analyzed using thematic analysis to explore the lived experience of adults who stutter.ResultsSelf-efficacy emerged as a strong positive predictor of quality of life for adults living with a stuttered speech disorder. Stuttered speech frequency was a moderate negative predictor of self-efficacy. Major qualitative themes identified from the interviews with the participants were: encumbrance, self-concept, confidence, acceptance, life-long journey, treatment, and support.ConclusionResults provide clarity on the predictive value of self-efficacy and its relationship to quality of life and stuttered speech frequency. Findings highlight that the unique life experiences of adults who stutter require a multidimensional approach to the assessment and treatment of stuttered speech disorders.     

Math Talk and Student Strategy Trajectories: The Case of Two First Grade Classrooms

This study investigated different math-talk facilitations, and conceptualized the teachers' talk moves for productive student mathematics discussions. Our findings suggest that students' strategy development is supported by talk moves coordinating a wide range of student strategies, representations and discussions that are at a process-level and maintain student ownership of ideas, and transitional strategies that connect students' beginning ideas with target strategies.     

Executive functioning and health-related quality of life in pediatric sickle cell disease

Research consistently indicates that children with sickle cell disease (SCD) face multiple risk factors for neurocognitive impairment. Despite this, no empirical research to date has examined the impact of neurocognitive functioning on quality of life for this pediatric group. Thus, the current study aims to examine the relationship between executive functioning and quality of life in a sample of children with SCD and further explore psychosocial and family/caregiver resources as moderators of this relationship. A total of 45 children with SCD aged 8 to 16 years and their caregivers completed measures of quality of life, behavioral ratings of executive functioning, and psychosocial functioning. Hierarchical linear regression models were utilized to determine the impact of executive functioning on quality of life and further test the interaction effects of proposed moderating variables. Controlling for age, pain, and socioeconomic status (SES), executive functioning was found to significantly predict child- and parent-reported quality of life among youth with SCD. Psychosocial resources of the primary caregiver or family was not found to moderate the relationship between executive functioning and quality of life. These results provide the first empirical evidence that lower executive skills negatively predict quality of life for children with SCD, supporting clinical and research efforts which aim to establish efficacious interventions that target cognitive decrements within this pediatric population.