The effects of massage velocity on heart rate and heart rate variability in healthy infants: A randomized crossover study

BackgroundInfant massage, in which mothers stroke their infant’s skin slowly and gently, can cause pleasant sensations in the infant that can be affected by the velocity of massage. However, the massage velocity at which infants feel the most pleasant sensations remains unclear.ObjectiveTo investigate the effects of massage velocity on heart rate (HR) and HR variability (HRV) in healthy infants.MethodTwenty-two infant-mother dyads two to seven months of age were recruited. Mothers stroked their infant’s skin at three massage velocities (5.0, 7.5, and 10.0 cm/s) in a randomized order for 15 min. The rhythm of massage velocity was calculated according to the length of three body areas. The massage velocity of the mothers was regulated using a metronome. HR and HRV (high frequency [HF] and low frequency [LF]) were measured at rest and during massage for each velocity. The effects on pleasantness were evaluated using percent change in median baseline value compared with median values for the three massage velocities. Statistical analysis was performed using analysis of variance mixed effect models to exclude “period” and “carryover” effects during massage.ResultsWhen measuring HF, massage (7.5 cm/s) caused a significant increase in pleasantness compared with 10.0 cm/s (p = 0.04). The HR and LF/HF ratio were not significantly changed between velocities.ConclusionResults of this study suggested that a massage velocity of 7.5 cm/s was the most pleasant for infants. Future research should investigate the relationship between an infant massage by optimal velocity and infant development in longitudinal studies.     

工作反刍及其“双刃剑”效应

工作反刍指在没有要求其出现的情境下, 有意识的、重复发生的工作方面的相关想法, 分为工作相关情感反刍与工作相关问题解决沉思两个维度。工作反刍对个体健康、工作及幸福感的影响有“双刃剑”效应。持续性认知理论、压力认知激活模型与认知资源视角理论, 可以解释该效应的内在机制。未来研究应分析影响双刃剑效应的边界条件, 寻求减少消极效应、增加积极效应的途径, 拓展其双刃剑效应心理机制的分析视角和该效应的作用层面。     

Is analytical psychology a religion? In statu nascendi

This paper elucidates and discusses Jung's conceptions of the relation between psychology, psychotherapy and religion.     

西方汉学家葛瑞汉《墨子》研究述评——以墨子十论为重心

本文介绍著名西方汉学家葛瑞汉的墨子研究,主要以＂墨子十论＂为讨论重点。本文第一部分简介葛瑞汉之学术研究概况;本文第二部分分别讨论葛氏提出＂墨分为三＂与十论篇次关系之理论,共有：其一,《非攻上》归属问题与《天志》诸篇关系;其二,《非命》诸篇之错简问题;其三,导致三派分歧的主题研究三大主题,逐一述评葛氏之研究成果,并参照相关文献,检讨其得失所在;本文第三部分则略论葛氏提出的墨家分派及其＂十论＂研究的效用与限制;最后则说明中、西学界治学方法、风格之异同,而吾人若能两者并参,截长补短,则必能双赢。     

Learning from the patient: The East,synchronicity and transference in the history of an unknown case of C.G. Jung

This article presents the history of one until now unknown case of C.G. Jung: Maggy Reichstein. Born in Indonesia in 1894 in a very aristocratic family, she brought her sister to Zurich to be treated by Jung in 1919, and later she herself was in analysis with him. Jung used her case as example in his lecture in 1937 on the realities of practical psychotherapy, relating it to the process of transference and countertransference. Jung deepened his studies in Eastern psychology after a series of dreams she had, which culminated in the Yoga Kundalini Seminars. She was also the case presented in his article of 1951 on the concept of synchronicity. Jung wrote that her case, concerning synchronicity, remained unique in his experience. Jung also published some of her mandalas. He considered her able to understand his ideas in depth. Reichstein was for Jung an important case, which challenged and triggered his interests in different subjects.     

Two Key Differences between Science and Philosophy

C. S. Peirce made the following claim: If science reveals truth, then consensus among scientists can be expected in the limit. This article does not dispute this claim; it simply assumes it. On the basis of this assumption, the following question is asked: Is it possible to extend Peirce's claim to philosophy in a natural way? It is argued that two important differences between science and philosophy strongly militate against such an extension. Does this mean that there is no truth to be found in philosophy? Are there, perhaps, different kinds of truth (scientific, philosophical, religious, and so on)? But such questions, though related to the present investigation, are nevertheless well beyond the scope of this article.     

LKB1蛋白在食管鳞癌组织中的表达及意义

为了探讨肝激酶B1（LKB1）蛋白在食管鳞癌组织中的表达水平及其与食管鳞癌临床特征及生存期的关系,应用免疫组化方法检测120例食管鳞癌患者组织中LKB1蛋白表达情况并对诸多临床特征进行相关性分析研究,发现LKB1蛋白在食管癌旁正常组织的阳性表达率高于癌组织;LKB1蛋白表达与患者年龄、性别、肿瘤部位、病变长度及浸润深度无关而与分化程度、淋巴结转移及临床分期（TNM）相关,且LKB1蛋白阴性组预后较阳性组差.可见LKB1视为抑癌基因影响食管鳞癌的预后,可能成为食管鳞癌新型的临床预后指标之一.     

难治性丙型肝炎研究新进展

随着聚乙二醇化干扰素(IFN)的普及应用和慢性丙型肝炎规范化治疗的开展,其治愈率不断提高.但疗效不佳的慢性丙型肝炎患者不断积累,难治性慢性丙型肝炎患者成为临床医生必须面对的挑战.难治性丙型肝炎患者应当分为两类,第一类为“难治疗”性慢性丙型肝炎患者,该类患者由于宿主条件限制,不能耐受IFN联合利巴韦林(RBV)的标准治疗,如儿童和老年人、慢性肾功能衰竭患者等.第二类为“难治愈”性慢性丙型肝炎患者,该类患者可以耐受标准治疗方案,但按照应答指导的治疗原则(RGT)治疗后,效果仍然不佳或复发.本文就近年关于难治性丙型肝炎的研究进展,从难治性丙型肝炎的定义、机制、治疗诸方面作一综述.     

EGFR突变NSCLC二线TKIs治疗优化选择

恶性肿瘤的治疗已经进入驱动基因指导下的个体治疗时代,肺癌患者应该进行多基因检测,特别是表皮生长因子受体（EGFR）基因突变。EGFR基因突变的非小细胞肺癌（NSCLC）患者,如果一线接受了化疗,二线应该选择表皮生长因子受体一酪氨酸酶抑制剂（EGFR—TKIs）。EGFR基因突变的NSCLC患者一线EGFR—TKIs治疗失败后,二线治疗应该是个体化合理选择,包括局部放疗、化疗和继续EGFR—TKIs。目前一代和二代EGFR—TKIs药物之间未见到显著疗效差别。第三代EGFR—TKIs是目前的EGFR—TKIs耐药后的最有希望的选择,特别是针对T790M突变耐药。