无语境条件下汉语词类歧义词的意义激活

以单字词为实验材料,采用启动命名任务,在孤立词条件下考察了汉语词类歧义词不同意义激活的时间进程特点。实验发现,歧义词的两种意义都能被激活,但主要意义激活得较早,次要意义激活速度较慢;当两种意义都激活之后,次要意义的激活水平降低,而主要意义仍维持在一定激活水平。结果表明,汉语词类歧义词的多重激活过程会受到意义相对频率的影响。     

Systemic and local administration of estradiol into the prefrontal cortex or hippocampus differentially alters working memory

The influence of estradiol on learning and memory is dependent on a number of factors. The effects of physiological levels of estradiol on the acquisition of a spatial working memory task mediated by the prefrontal cortex (PFC) and the hippocampus were examined in Experiment 1. Ovariectomized Long-Evans rats received daily injections of estradiol or vehicle were tested on the win-shift version of the radial arm maze. A high dose of estradiol benzoate (5 microg) enhanced acquisition of the task, whereas a low dose of estradiol (0.3 microg) increased the number of errors committed over 17 days of testing. Experiment 2 was conducted to examine site-specific influences of estradiol on spatial working memory in well-trained rats. Saline and estradiol cyclodextrin (0.1 and 0.9 microg) were infused into the prelimbic region of the PFC or dorsal hippocampus 40 min prior to testing on the win-shift task. Infusions of estradiol into both brain areas attenuated saline-infusion disruptions in working memory. Specifically, the higher dose of estradiol facilitated working memory when infused into the PFC, whereas the lower dose of estradiol facilitated performance when infused into the dorsal hippocampus. Moreover, working memory was significantly impaired 24 h after infusions of estradiol into the dorsal hippocampus but not the PFC. These data provide further evidence for the notion that estradiol can dose-dependently alter memory processes and suggest that facilitation or disruptions of working memory by estradiol are site- and time-specific.     

Cognitive and Behavioral Contributions to Depression Severity,Quality of Life,and Functioning Among People Living With HIV in South Africa

Cognitive-behavioral treatments for depression typically address both behavioral (e.g., activation) and cognitive (e.g., rumination) components, and consequently improve quality of life (QOL) and function in high-resource settings. However, little is known about the cross-cultural applicability and relative contribution of these components to depression symptom severity, QOL, and functional impairment in South Africa and other resource-limited global settings with high HIV prevalence rates.Persons with HIV (N = 274) from a peri-urban community outside Cape Town, South Africa, were administered multiple measures of depression (Hamilton Depression Scale, Centre for Epidemiological Studies Depression Scale, South African Depression Scale), cognitive and behavioral components related to depression (Ruminative Response Scale, Behavioral Activation for Depression Scale), and measures of QOL and functioning (Sheehan Disability Scale, Quality of Life Enjoyment and Satisfaction Scale—Short Form). Multiple linear regression models were fit to assess the relative contribution of behavioral and cognitive components to depression severity, QOL, and functional impairment in this population.Models accounting for age and sex revealed that lower levels of behavioral activation (BA) were significantly associated with all measures of depression, as well as with QOL and functional impairment (all ps < .01). Rumination was associated with all measures of depression (all ps < .01), but not with QOL or functional impairment.The consistent and unique association of BA with depression, QOL, and functional impairment bolsters its importance as a treatment target for this population.     

Divided Visual Attention and Left Hemisphere Activation Among Psychopathic and Nonpsychopathic Offenders

Recent divided attention studies suggest the impulsive antisocial behavior of psychopaths may be related to deficient processing of information under conditions that place substantial demands on left-hemisphere-specific processing resources (left hemisphere activation (LHA) hypothesis; D. S. Kosson [1996, 1998]). To examine performance under conditions constraining eye movements and covert shifts of attention, 26 psychopathic and 46 nonpsychopathic inmates completed a divided attention task in which lateralized stimuli appeared briefly and simultaneously in the left visual field (LVF) and right visual field (RVF) of a monitor. Targets were either presented primarily in the RVF to induce LHA or were equiprobable in LVF and RVF to promote equal activation (EA) of left and right hemisphere resources. Psychopaths were less accurate than nonpsychopaths only under LHA conditions; within-group comparisons also revealed a substantial decrement from EA to LHA only in psychopaths. Thus, psychopaths’ performance deficits were specific to conditions priming left hemisphere resources asymmetrically.     

Genetic counseling for a family with two distinct anomalies: A case report of a neural tube defect and 5p- syndrome in a fetus

A couple presented for genetic counseling because of an elevated maternal serum alpha fetoprotein. Ultrasound examination revealed the presence of a neural tube defect. The couple declined an amniocentesis, but chose serial ultrasound evaluations instead. Ultrasounds eventually identified microcephaly, but the couple continued to decline amniocentesis. After the child's birth, the diagnosis of 5p- syndrome was made. The couple's decision not to have an amniocentesis allowed the family their right to autonomy; however, prenatal chromosome analysis would have provided this couple with a great deal more prognostic information. We discuss the conflict between a counselor's duty to respect a client's freedom vs. duty to care for a client's welfare. We address issues of nondirective counseling and the need for more studies looking at the decision-making process in prenatal diagnosis.     

语音在维——汉双语者汉字识别中的作用

采用语音启动技术,以第二语言为汉语的46名维吾尔族大学生为研究对象,考查了语音在维-汉双语者汉字识别中的作用.结果发现,维吾尔族被试在命名任务和词汇判断任务中都获得了语音启动效应,语义启动效应只出现在词汇判断任务中.结论:语音在维吾尔族大学生汉字识别中是自动激活的,而且语音的自动激活参与了语义通达.     

干扰子的激活、抑制及其加工时程

针对有关干扰子激活和抑制加工的时程研究存在的分歧,采用干扰效应和负启动效应双指标,探讨不同知觉负载水平下干扰子的激活和抑制及其加工时程问题。结果显示：在同一实验条件下采用干扰效应和负启动效应双指标可将干扰子加工过程分离为激活和抑制两个阶段;激活加工时程发生在选择性注意早期,抑制加工时程发生在选择性注意的早期至中期之间。这一结果与Lavie等的推测及认知神经科学研究成果均有异同。     

Emotional reactivity and self-regulation in relation to personality disorders

Associations of both reactive and regulative temperamental features with personality disorders (PDs) are investigated in a sample of 162 normal controls and 89 psychiatric inpatients. Reactive and regulative temperamental features were assessed by means of the BIS/BAS Scales and the Attentional Control Scale. Dimensional PD scores were obtained by using the ADP-IV. All PDs were characterized by low levels of effortful control, cluster C PDs by high BIS and cluster B PDs by high BAS. For several PDs, BIS and effortful control interacted: BIS was only related to severe PD pathology if effortful control was low. Clinical implications of these findings are discussed.     

不公平感及相关决策的认知神经机制

公平是人类社会生活的基本规范之一,不公平感及其相关决策则是研究者们关注的重要课题。长期以来,该领域的研究一般采用最后通牒博弈或其变式展开。大量脑成像研究探查了关于不公平感及相关决策的认知神经机制,尤其集中探讨了最后通牒博弈的回应者对不公平提议进行反应的脑区及其对应功能。经常得到关注的脑区包括了前脑岛、前扣带皮层、背外侧前额叶、内侧前额叶、杏仁核和颞顶交界等。对特殊人群的不公平感及相关决策进行研究可以帮助检验或澄清上述重要脑区及脑网络在不公平感及相关决策中扮演的角色,同时也阐释特殊人群的社会认知功能的特点。近年来,相当数量的研究关注了不同情境因素(包括分配方案相关因素和社会情境相关因素)调制不公平感及相关决策的过程,并讨论其背后的认知神经机制。未来的研究更应利用多模态数据分析方法,同时结合基因和激素层面的研究,以期深入对不公平感及相关决策的心理和生理机制的理解。