Motor sequence learning in children with recovered and persistent developmental stuttering: preliminary findings

PurposePrevious studies have associated developmental stuttering with difficulty learning new motor skills. We investigated non-speech motor sequence learning in children with persistent developmental stuttering (CWS), children who have recovered from developmental stuttering (CRS) and typically developing controls (CON).MethodsOver the course of two days, participants completed the Multi-Finger Sequencing Task, consisting of repeated trials of a10-element sequence, interspersed with trials of random sequences of the same length. We evaluated motor sequence learning using accuracy and response synchrony, a timing measure for evaluation of sequencing timing. We examined error types as well as recognition and recall of the repeated sequences.ResultsCWS demonstrated lower performance accuracy than CON and CRS on the first day of the finger tapping experiment but improved to the performance level of CON and CRS on the second day. Response synchrony showed no overall difference among CWS, CRS and CON.Learning scores of repeated sequences did not differ from learning scores of random sequences in CWS, CRS and CON. CON and CRS demonstrated an adaptive strategy to response errors, whereas CWS maintained a high percentage of corrected errors for both days.ConclusionsOur study examined non-speech sequence learning across CWS, CRS and CON. Our preliminary findings support the idea that developmental stuttering is not associated with sequence learning per se but rather with general fine motor performance difficulties.     

Hysteresis behaviour of psychobiological variables during exercise

ObjectivesThe rating of perceived exertion (RPE) and the heart rate (HR) have been widely studied and monitored during exercise, but their hysteresis behaviour is still unexplored. Our aim was to study the hysteresis behaviour of RPE and HR in triathletes and non-athletes.DesignCross-sectional study.MethodEighteen triathletes at different competitive levels (elite n = 9, non-elite n = 9) and ten students were tested while cycling and running, using a pyramidal protocol (incremental/decremental workloads). The hysteresis area, considered positive when values of the dependent variables (RPE and HR) at the same workload were higher in the decremental phase than in the incremental phase, and vice versa for the negative areas, was calculated in all tests. The Wilcoxon matched-pairs test and Kruskal Wallis ANOVA were applied to detect intra- and inter-group differences, respectively, of RPE and HR values during the incremental and decremental phases, as well as between cycling and running.ResultsThe following results were observed: a) an incoherent relationship of RPE with HR and workload, b) positive hysteresis areas of RPE and HR in all groups during cycling and running, c) a partial negative hysteresis area of RPE, but not of HR, in the triathlete groups, d) larger hysteresis areas of RPE and HR in students than in triathletes, and e) larger hysteresis areas in cycling than in running.Conclusionsthe study of the hysteresis behaviour of RPE and HR reveals the history dependency of both variables, highlights their incoherent or non-unique relationship during a pyramidal exercise, and questions their widely assumed linear association to workload intensity. The hysteresis area is proposed as a new non-invasive marker of exercise stress and tolerance that should be further investigated.     

Muscular fitness,motor competence,and processing speed in preschool children

ABSTRACT

The aim of this study was to examine the relationship between muscular fitness and motor competence and processing speed in preschool children. Eighty-four preschool-aged children were recruited and underwent assessments for muscular fitness (muscular endurance and power), motor competence, and then participated in an auditory oddball task. The findings showed that muscular fitness and motor competence were associated with shorter reaction times after controlling for confounding factors. These findings provide tentative support for a positive association between muscular fitness and motor competence and processing speed in preschool children.

abbreviations:

Reaction time (RT); Institutional Review Board (IRB); Basic Motor Ability Test-Revised (BMAT); Body mass index (BMI); Preschool Children Fitness Programme (PCFP); Intraclass correlation coefficients (ICC); Thinking Creatively in Action and Movement test (TCAM); Inter-stimulus interval (ISI); Insulin-like growth factor 1 (IGF-1); Brain-derived neurotrophic factor (BDNF)     

Ageing effects on the attention demands of walking

Attention demands of walking were determined in six male and six female young adults (mean 26.3 yr) and 12 gender-matched healthy, active older adults (mean 71.1 yr) using a dual task procedure with a reaction time (RT) secondary task. In three conditions an auditory stimulus, a visual stimulus and both stimuli (auditory/visual) were presented. Relative to no-walking baselines, increased RT was found in all conditions revealing an attentional cost of normal walking. When participants traversed the laboratory walkway and also positioned one of their feet within a target area on the ground, attention demands were greater than in unconstrained walking. In the targeting task, RTs to the visual stimulus were longer than for the auditory stimulus due to the interference associated with viewing both the stimulus monitor and the foot-target. Older participants' RTs in the visual and auditory/visual conditions, but not in the auditory condition, were significantly longer than for the young group in both walking tasks but RTs for young and older adults were not different in no-walking baseline trials. Inspection of mean RT functions at time intervals following gait initiation (0-3000 ms from the first step) suggested a fluctuating attentional cost of walking with increased demands associated with contingencies requiring step length regulation. The findings have applied significance in demonstrating the possibility of increased falls and pedestrian accident risk in older individuals in dual task situations such as road crossing.     

Syntactic, prosodic, and semantic processes in the brain: evidence from event-related neuroimaging

The neural network supporting aspects of syntactic, prosodic, and semantic information processing is specified on the basis of two experiments using functional magnetic resonance imaging (fMRI). In these two studies, the presence/absence of lexical-semantic and syntactic information is systematically varied in spoken language stimuli. Inferior frontal and temporal brain areas in the left and the right hemisphere are identified to support different aspects of auditory language processing. Two additional experiments using event-related brain potentials investigate the possible interaction of syntactic and prosodic information, on the one hand, and syntactic and semantic information, on the other. While the first two information types were shown to interact early during processing, the latter two information types do not. Implications for models of auditory language comprehension are discussed.     

The role of inferior frontal cortex in phonological processing

Recent neuroimaging studies of language processing are examining the neural substrate of phonology because of its critical role in mapping sound information onto higher levels of language processing (e.g., words) as well as providing codes in which verbal information can be temporarily stored in working memory. However, the precise role of the inferior frontal cortex in spoken and written phonological tasks has remained elusive. Although lesion studies have indicated the presence of selective deficits in phonological processing, the location of lesions underlying these impairments has not revealed a consistent pattern. Despite efforts to refine methods and tasks, functional neuroimaging studies have also revealed variability in activation patterns. Reanalysis of evidence from these neuroimaging studies suggests that there are functional subregions within the inferior frontal gyrus that correspond to specific components of phonological processing (e.g., orthographic to phonological conversion in reading, and segmentation in speech).     

Antiaggressive and motor effects of the DA release inhibitor CGS 10746B

In the present study the effects of a wide range of doses of the dopamine release inhibitor CGS 10746B were evaluated in spontaneous activity and in aggressive behaviour using the paradigm of isolation‐induced aggression. The two higher doses (8 and 16 mg/kg) produced a decrease in spontaneous motor activity. Antiaggressive effects were observed after administration of doses from 4 mg/kg upwards. At this dose, CGS 10746B diminished threat and attack, and although an increase in immobility was observed, no impairment of other motor behaviours was presented. With higher doses, aggression was practically abolished but with a concomitant effect on many other behaviours. When animals were separated depending on their latency of attack, those that showed a long attack latency (LAL) presented a stronger response to 4 mg/kg than those that had a short attack latency (SAL), which were not affected in their aggression by this dose. We can conclude that presynaptic dopamine function is necessary for the normal expression of aggressive behaviours, since CGS 10746B reduces aggression at doses that do not affect spontaneous motor activity. Aggr. Behav. 27:382–390, 2001. © 2001 Wiley‐Liss, Inc.     

Visual-Motor Integration Problems in Low Birth Weight Infants

This paper represents a review of the research that focuses on a population of strong clinical interest on a national and international scale—infants born with low birth weight (LBW). Among the numerous developmental deficits commonly associated with this group, one of the most frequently cited problems is poor fine- and visual-motor integration. In addition to the direct perceptual-motor development concern, the literature provides a reasonable case that such deficits place this population at increased risk for subnormal academic performance and difficulties with specific daily living (self-help) activities. By assessing the infant at an early age and designing specific strategies for intervention, clinical psychologists can play a major role in improving fine- and visual-motor behavior in this population.     

条件反射性免疫增强的研究进展

综述了国内外研究条件反射性免疫增强的主要成果;介绍了相关实验所使用的刺激物,观测的指标和实验程序;探讨了一些脑区如下丘脑、岛叶皮质,神经通道如交感和迷走神经,多种神经内分泌激素如β-内啡肽、干扰素以及白细胞介素如IL-1等在条件反射性免疫增强中的介导作用     

Dissimilarity cumulation theory and subjective metrics

We present a new mathematical notion, dissimilarity function, and based on it, a radical extension of Fechnerian Scaling, a theory dealing with the computation of subjective distances from pairwise discrimination probabilities. The new theory is applicable to all possible stimulus spaces subject to the following two assumptions: (A) that discrimination probabilities satisfy the Regular Minimality law and (B) that the canonical psychometric increments of the first and second kind are dissimilarity functions. A dissimilarity function Dab for pairs of stimuli in a canonical representation is defined by the following properties: (1) a≠b?Dab>0; (2) Daa=0; (3) If and , then ; and (4) for any sequence {a_nX_nb_n}_n∈N, where X_n is a chain of stimuli, Da_nX_nb_n→0?Da_nb_n→0. The expression DaXb refers to the dissimilarity value cumulated along successive links of the chain aXb. The subjective (Fechnerian) distance between a and b is defined as the infimum of DaXb+DbYa across all possible chains X and Y inserted between a and b.