Intervention effects and relative variation as dimensions in experts' use of visual inference

Recent research indicates that when analyzing graphically presented single-subject data, subjects trained in visual inference appear to attend to large changes between phases regardless of relative variation and do not differentiate among common intervention effect patterns. In this follow-up study, experts in applied behavior analysis completed a free-sort task designed to assess the effects of these dimensions on their use of visual inference. The results indicate that they tended to differentiate among common intervention effect patterns but did not attend to relative variation in the data.     

PILLS OR SKILLS FOR HYPERACTIVE CHILDREN

The controversial nature of drug treatment of hyperactivity, the incidence and sequelae of hyperactivity, and problems of differential diagnosis of hyperactivity versus aggression were discussed. The effects of psychostimulant medication and behavior therapy on hyperactive children were reviewed with regard to effects on their social and academic behavior. Both treatments have resulted in clear short-term changes in social behavior but neither long-term academic nor long-term social effects have been shown with either treatment. Short-term effects on academic behavior have resulted from behavioral interventions but not from psychostimulants. However, the interventions have been too brief to allow one to draw unequivocal conclusions about the clinical efficacy of behavioral treatments. Although there have been long-term evaluations of psychostimulant therapy, there have not been any evaluations of long-term behavioral treatment programs for hyperactive children. Given the salutary short-term effects of behavior therapy with hyperactive children, extended clinical trials of behavior therapy need to be conducted. Finally, specific directions are suggested for future research.     

Cry analysis detects subclinical effects of prenatal alcohol exposure in newborn infants

The threshold, latency, and peak fundamental frequency (basic pitch) of crying were sensitive to the subclinical effects of prenatal alcohol exposure through the first month of postnatal life. Whereas infants with prenatal alcohol exposure showed a lower cry pitch and higher cry threshold at 2 days of age, higher pitched cries, typical of nervous system insult, were evident at 14 and 28 days. A longer latency was also evident at 14 days.     

时序信息加工机制及其通道效应的实验研究

研究由两个实验组成,实验一采用纯粹的视听方式,以线段长度和声音频率为材料,对时序信息的加工方式（自动加工与控制加工）、编码特点（时序信息是何时编码的）以及通道效应进行了研究。实验二以汉字为材料重复实验一的过程;结果表明,时序信息的加工存在视听通道效应,其机制源于记忆,且与实验材料的加工深度以及加工方式有关;时序信息既包含有自动加工,又包含有控制加工。视觉刺激倾向于自动加工,而听觉则倾向于控制加工;时序信息是在项目学习时编码获得的,而不是在提取时建构的。     

Ratio size and cocaine concentration effects on oral cocaine-reinforced behavior.

Monkeys were given a choice between cocaine solutions and water under concurrent fixed-ratio reinforcement schedules. The operant response was spout contact. Six rhesus monkeys served as subjects. The cocaine concentration was varied from 0.0125 to 0.8 mg/ml, and the fixed-ratio value was varied from 8 to 128. Cocaine maintained higher response rates than did water over a wide range of conditions. Response rate and number of cocaine deliveries per session were inverted U-shaped functions of concentration. These functions were shifted to the right as the fixed ratio was increased. The number of cocaine deliveries was more persistent as fixed-ratio value was increased when the unit dose was larger rather than smaller. Cocaine consumption was analyzed as a function of unit price (fixed-ratio value divided by cocaine concentration), and unit price accounted for between 77% and 92% of the variance in cocaine consumption for individual monkeys. The current data support the claim that a drug's reinforcing effects increase directly with dose and underscore the need to gather parametric data when examining the effects of experimental manipulations on a drug-reinforced baseline.     

Inter-event differences in action memory

Two experiments examined the effect of verb-noun connectivity on recall of simple action phrases, under motor and nonmotor encoding conditions. Connectivity, measured by associative overlap and rated belongingness, was found to make a difference. High-connectivity pairs are better recalled than low-connectivity pairs. Primacy effects are absent with low-connectivity pairs, but generally present with high-connectivity pairs—irrespective of encoding conditions. Inter-item action phrase differences thus influence the effects studied in action memory research. The results were discussed in terms of strategic and nonstrategic conceptions of memory for actions.     

项目在不同间隔时间呈现过程中的系列位置效应

以中国汉字为材料,考察不同中数比率（０．６,０．８和１．０）时,系列位置曲线不同部分性质的分化,结果说明,系列位置曲线不同部分的性质,是项目间隔时间和其时间变化的中数比率共同作用的结果,发现项目间隔时间变化中数比率所起作用更大,在项目呈现时间相同时,项目隔间的时间长短,决定项目之间的辨别程度,也影响到对项目正确提取的百分数。     

Similar consumption and responding across single and multiple sources of drug

Two experiments were conducted to assess whether total response output and total consumption would be similar when drugs are available from single and multiple sources of reinforcement, as predicted by behavioral economics. In Experiment 1, cigarette-deprived smokers were exposed to a concurrent-chains schedule in which equal fixed-ratio schedules served as the initial links, and different reinforcer magnitudes (i.e., number of cigarette puffs) were arranged across alternatives. After the session, obtained unit price was calculated and imposed in the next session when a different number of puffs was available according to a single fixed-ratio schedule. Thus, the unit price at which cigarette puffs could be earned was yoked within subjects across the single and concurrent-chains schedules. When plotted as a function of unit price, similar consumption and response rates were usually obtained across these schedules. Experiment 2 addressed a weakness of Experiment 1, namely, that responding was allocated exclusively to the larger reinforcer magnitude in concurrent-chains conditions, and therefore this schedule may have functioned as a single schedule. In Experiment 2, subjects were instructed to alternate responding between the two alternative schedules. Instructions produced approximately equal response allocation between the two alternatives. Again, similar consumption and response rates were observed across the single and instructed concurrent-chains schedules. These findings are discussed in the context of direct effects and behavioral economics perspectives of drug self-administration.     

Principles of good clinical practice (GCP) in clinical research

Good Clinical Practice is an international quality standard for conducting trials that involve participation of human subjects. Currently, the most widely accepted international document forming the base for GCP is the ICH Harmonised Tripartite Guideline for GCP, which defines in detail the responsibilities and obligations of parties engaged in clinical research. The purpose of this paper is to analyse how compliance with GCP provides protection of the trial subjects and assures quality and credibility of the data obtained. An earlier version of this paper was presented at a symposium, Scientific Misconduct: An International Perspective, organised by The Medical University of Warsaw, 16 November, 1998.     

中文双字词的具体性效应研究

通过词汇决定任务来考察中文双字词的具体性效应,并检验双重编码理论和语境有效性模型对具体性效应的预测。实验一在刺激单独呈现的条件下操纵词的频率,结果发现在低频的情况下对抽象词的判断时间显著长于具体词,但是在中频情况下没有显著差异;实验二用低频具体词和低频抽象词做重复启动实验,发现重复启动不能消除具体性效应;实验三为低频具体词和低频抽象词提供句子语境,结果发现在一致性句子语境条件下具体性效应消失。以上实验结果既不完全符合双重编码理论的预测,也不完全符合语境有效性模型的预测。