单克隆抗体的治病与“致病”

对单克隆抗体在病毒性疾病治疗和引起病毒感染增强两方面的作用进行了综述，分析了各自涉及的机理。指出于者是矛盾的统一体，辨证地看待是前提，深入研究是关键，合理和才是目标。     

Using targeted visceroception to improve interoceptive sensibility and emotion regulation

Focusing on one's body can improve the awareness and regulation of emotion. Interoception – sensing the physiological condition of the body, particularly of the viscera – appears to play an important role. While the majority of previous research studies have examined interoceptive sensitivity (i.e., detection of objectively measurable physiological changes), there has been relatively limited investigation of interoceptive sensibility (i.e., subjective awareness of those changes), and even fewer studies permitting causal conclusions. The current study is part of a randomised controlled trial on visceroception in the context of emotion regulation, using an 8-week intervention involving focused attention on either cardiac or gastrointestinal activity. Group differences in emotion regulation and reactivity were assessed using the Multidimensional Assessment of Interoceptive Awareness (MAIA), the Difficulties in Emotion Regulation Scale, and the Emotion Reactivity Scale (ERS). The findings suggest that focussed attention on gastrointestinal activity (i.e., gastroception), in particular, improves interoceptive sensibility and emotion regulation, as evidenced by increases on the MAIA's Noticing, Body Listening, and Self-regulation subscales, and decreases on the Arousal subscale of the ERS. Gastroception may make distinct contributions to the benefits of body focus in a research context where the gut is often overlooked.     

ON AGGRESSION TURNED AGAINST THE SELF

Deliberate self‐harm is a common presenting problem suffered by young people. Several patients referred to the NHS outpatient clinic where I work have been able to stop harming themselves during intensive psychoanalytic psychotherapy. In this paper, I shall discuss a variety of motives for persistent cutting by one adolescent girl. I am most interested to show how the healthier part of her personality overcame her motives for harming herself, and eventually allowed her to make use of my understanding of a sadomasochistic internal object that worked against us.