冠心病理想治疗方式的选择

冠心病的治疗包括针对高危因素病因和临床并发症的综合治疗。其中,药物治疗主要包括：抗凝／抗血小板、控制血压和调脂等。血管重建术主要包括：介入、搭桥、“杂交”手术和分子生物学治疗。药物治疗是冠心病各种治疗方法的基础,而血管重建术是现代治疗冠心病的重要手段。如何合理地选择治疗方案是临床医师面临的重要课题。     

冠心病的外科治疗

首例成功的冠状动脉旁路移植术（CABG）手术完成于1960年,随着体外循环技术的成熟,CABG手术得以不断发展。20世纪90年代,以非体外循环下冠脉旁路移植术（0PCAB）为代表的微创冠脉搭桥手术逐渐应用于临床,并取得满意的临床效果。尽管冠脉介入技术（PCI）以其创伤小的优点在冠心病的治疗方面蓬勃发展,但是CABG在远期通畅性方面仍然占据优势地位,因此CABG仍然是冠心病治疗的效果确定的一种方法。     

The effects of social influence on children's memory reports: the omission and commission error asymmetry

Children in two age groups (7 vs. 12 yrs, N= 174) individually interacted with a stranger and were later interviewed about this event. Right before the interview, each child encountered the stranger once again and he engaged in a conversation where he either suggested that a (central or peripheral) detail originally present in the event had actually not been there or that an originally non-present (central or peripheral) detail had in fact been there. It was hypothesized that the two types of misinformation would result in omission and commission errors respectively. The results showed that the social influence resulted in an asymmetric effect (i.e., more commission than omission errors). Importantly, we also found that the children made more errors with respect to the peripheral detail (a suitcase), compared to the central detail (a passenger). Younger children did not make more errors (neither omission nor commission errors) than older children.     

论神经哲学的兴起

人类心身问题的研究一直是科学界关注的热点。近年来,国外学者将神经科学与哲学研究统一起来,集合两门学科的研究方法、综合双方的研究成果,以此来共同推进人类心身问题的研究,因此诞生了一门介于神经科学和哲学之间的独立学科,它有着学科交叉的研究领域和特殊的跨学科研究方法,这门学科就是神经哲学。     

Trait Stability and Continuity in Childhood: Relating Sociability and Hostility to the Five-Factor Model of Personality

We investigated the continuity of personality constructs in the Oregon Youth Substance Use Project, a cohort-sequential study encompassing development from early childhood to adolescence with five annual or biennial assessments. Sociability and Hostility, assessed by teachers' ratings of children's behaviors at each assessment, were related to the traits comprising the Five-Factor model assessed by teachers' ratings at the fifth assessment. Confirmatory factor analysis demonstrated that Sociability and Hostility were reliably measured at each assessment, and these constructs were relatively stable over time (mean rank-order stability coefficients over intervals of 1-5 years were .50 and .43, respectively). Sociability was most strongly associated (positively) with Extraversion, and Hostility was most strongly associated (negatively) with Conscientiousness and Emotional Stability. No differences were found for younger versus older children. Implications for measuring childhood personality traits using teachers' reports of early childhood behavior are discussed.     

The Effects of the <Emphasis Type="Italic">Nobody’s Perfect</Emphasis> Program on Parenting Resourcefulness and Competency

We conducted an evaluation of Nobody’s Perfect Program involving 71 participants from Peterborough County, Canada. Prior to the program, parents completed demographic information, along with self-report measures assessing the types of interactions with their children, parent resourcefulness, knowledge and use of resources, parent competency and self-efficacy, which were completed again after the program and at a two month follow-up testing. In comparison to parents not earning certificates, parents earning certificates were younger and more likely to have completed previous parenting programs. As well, parents earning certificates demonstrated and maintained an increase in parenting resourcefulness, warm/positive parent-child interactions, sense of parenting competency and satisfaction, and use of community resources. The more sessions parents attended, the better their parenting resourcefulness and warm/positive parent-child interactions on completion and at follow-up, and the less their angry and punitive parenting at follow-up. Parents who had attended parenting programs before had higher parenting resourcefulness scores at entry. They left the program with increased levels of parenting resourcefulness, better parent-child interactions, and more effective child management skills. A number of recommendations are suggested to help facilitators of the program enhance service delivery and improve parental outcomes.     

Perceived Social Support and Caregiver Strain in Caregivers of Children with Tourette’s Disorder

The research on Tourette’s disorder (TD), a neuropsychological disorder consisting of motor and phonic tics, has largely focused on individuals with TD and not on the caregivers of children with TD. We investigated the effects of several variables on caregiver strain of caregivers of children with TD, including perceived social support, caregiver characteristics, and characteristics of the child’s disorder. An online survey was completed by 140 caregivers of children with TD between the ages of 6 to 18 years. We performed a path analysis to examine the outcome of caregiver strain in relation to the research variables. Our results indicated that caregiver age, symptom severity of the child’s TD, and perceived social support accounted for variance in caregiver strain, and that perceived social support was a partial mediator of child’s symptom severity and caregiver strain. Symptom severity and caregiver strain were also related to the presence of other comorbid disorders, such as Oppositional Defiant Disorder (ODD), anxiety, or Attention Deficit Hyperactivity Disorder (ADHD) when compared to children either having no other comorbid disorders or other types of disorders.