Recherche en santé et protection des données personnelles à l’heure du Règlement général relatif à la protection des données

France has a very rich legal framework, which defines the conditions of access and use of health data for scientific research purposes and ensures their protection. Currently, this legal framework is undergoing revision. The European regulation of April 27th 2016 on protection of natural persons in relation to the processing of personal data came into effect in EU member states since 25th May 2018 and substitute a rationale of administrative process for a rationale that empowers the researchers to document and prove compliance with the regulation (“accountability”). This regulation must be coordinated with the other regulation applicable to research in UE and with national law.     

Directives anticipées et autonomie de la personne en fin de vie

Advance directives are an instrument used to maintain patients autonomy in case they can no longer decide themselves, according to French law « patients rights and end of life ». However, analysis of the legal procedure does not lead to such a conclusion.     

Une base de données en sémantique du verbe : Semasit

In this article, we present Semasit, a semantic database for French verbs developed for the purposes of experimental research in psycholinguistics and neuropsychology. This database features the distribution of the agents and patients of 96 verbs of interpersonal relations, and 60 verbs of change of state, based on their probability of occurence for 100 participants. It also provides the free-association norms of these 156 verbs. The degree of imagery is also presented for some of them. For 24 verbs of interpersonal relations, this semantic database is completed by the distribution of the patients, when an agent and a verb are presented together. It also provides the free association norms of the patients in this case. This database in freely accessible and can be downloaded from the Internet: http://www.mshs.univ-poitiers.fr/lmdc/semasit/frame-index.htm.     

L’évaluation cognitive de la lecture au collège : synthèse des principaux outils de dépistage et de diagnostic des troubles spécifiques de la lecture et cognitifs associés

As reported by the Programme for International Student Assessment (PISA, 2012), almost 20% of French teenagers show difficulties in reading (OCDE, 2014). What are the French language tools the practitioner or educationalist (teacher, school doctor, psychologist, and speech-language pathologist) use to assess specific reading disorders for middle school students? The tools assessing reading comprehension skills, word-level reading skills and reading-related skills are presented by distinguishing the tools developed for screening of reading difficulties (the purpose of which is to detect early disease or risk factors for disease in large numbers of apparently healthy individuals) than them developed for diagnosing of reading difficulties (the purpose of which is to establish the presence [or absence] of disease as a basis for treatment decisions in symptomatic or screen positive individuals). This synthesis allows to identify their interests and limits, and to consider new tools respecting five essential criteria: (1) the tool structure must be based on recent theoretical models specific at the middle school, (2) the tool must assess reading comprehension skills (with control of listening comprehension skills) and the mastery of two word-level reading procedures (lexical and sublexical), (3) the tool must measure a set of reading-related skills such as phonological awareness, phonological short-term memory, rapid serial naming and morphological awareness, (4) the experimental material (vocabulary control) and the standardization must be recent or updated and (5) the speed must be measured accurately.     

Où en est t’on du Big Data en médecine ?

Opening of medical datas and files is nowadays an important challenge. French Government increments new rules to allow access to these data files.     

Evaluation of early relational disturbance in high-risk populations: Borderline personality disorder features,maternal mental state,and observed interaction

Despite the longstanding theoretical association in the attachment literature between maternal trauma history and disturbances in the mother–infant interaction, few studies have investigated mechanisms of transmission of traumatogenic relational patterns in high-risk mother–infant dyads. This study investigated interrelationships among maternal trauma history, distorted maternal representations (DMRs, i.e. disturbed thoughts and feelings about the infant and self-as-parent), maternal mentalisation (i.e. capacity to conceive of self and other's intentions in terms of mental states including thoughts, feelings, and desires), and quality of interaction in a clinical sample of mothers with Borderline Personality Disorder (BPD) features and their infants (N = 61). Measures used included the Childhood Trauma Questionnaire, Parent Development Interview, Mother–Infant Relationship Scale, Borderline Symptom Checklist-23, and the Emotional Availability Scales. The results indicated BPD features mediated the relationship between maternal trauma history and DMRs predicting disturbance in interaction. In addition, analyses showed that maternal mentalisation had a buffering effect between DMRs and maternal non-hostility and yet the severity of BPD features moderated the relationship between mentalisation and DMRs. The findings suggest postpartum borderline pathology may adversely impact the experience of being a parent for women with a relational trauma history including deficits in mentalisation (i.e. hypermentalising) and disturbances in the mother–infant interaction. Implications for research and clinical practice are discussed.     

胚胎干细胞源性配子细胞的诞生对伦理学的冲击

胚胎干细胞在伦理学界引发的争论尚未平息,胚胎干细胞源性配子的诞生又在更深层次对伦理学产生了新的冲击.ESDG将在解决人类生殖问题中作出重要贡献,特别是给合法结婚的同性恋者带来了拥有带有自身遗传性状后代的希望.但是,这方面的进展势必会与伦理学产生冲突,并且有多方面的伦理问题需要人类慎重考虑.     

Les nouvelles technologies au service des personnes âgées : entre promesses et interrogations - Une revue de questions

Based on a literature review, this article proposes to discuss the psychosocial stakes dependent for the use of new technologies for the elderly. This reveals that if these devices have undeniable assets which can contribute to improve comfort and with the quality of life of the elders, he does not remain about it less than the fast development of these technologies also cause a series of interrogations relating to the maintenance of the psychic and social integrity of these users. These systems can thus cause a new form of dependence (with the technical assistance) and accentuate - paradoxically - the stigmatization of people by the construction of a new profile: “the technically assisted elders”.