Dichotic listening,executive functions and grey matter cortical volume in patients with schizophrenia and healthy controls

Schizophrenia is characterized by cognitive impairment, especially in relation to executive functions. Brain structural abnormalities are also often seen in schizophrenia although little is known of the relationship between cognitive impairment and structural brain changes. Our aim was therefore to investigate this relationship further using MRI and a dichotic listening (DL) task with simple speech sounds and with instructions to focus attention and report only from the left or right ear stimulus. When instructed to focus attention on the left ear syllable a cognitive conflict is induced requiring the allocation of executive resources to be resolved. Grey matter (GM) volume was measured with MRI from four volumes of interests (VOIs), left and right frontal and temporal cortex, respectively, and correlated with DL performance. The results showed significant differences between the groups in their ability to focus attention on and report the left ear stimulus, which was accompanied by reduced GM volume in the left frontal and right temporal lobe VOIs. There was also a significant positive correlation between left frontal GM volume and performance on the DL task, for the groups combined. The results did not support a conclusion that an impairment in cognitive function in schizophrenia was driven by an corresponding impairment in brain structure, since there were no significant correlations when the groups were analyzed separately. It is however concluded that patients with schizophrenia are impaired in executive functions and that they also show reduced GM volumes in left frontal and right temporal lobe areas, compared to healthy controls.     

A structural‐phenomenological typology of mind‐matter correlations

We present a typology of mind‐matter correlations embedded in a dual‐aspect monist framework as proposed by Pauli and Jung. They conjectured a picture in which the mental and the material arise as two complementary aspects of one underlying psychophysically neutral reality to which they cannot be reduced and to which direct empirical access is impossible. This picture suggests structural, persistent, reproducible mind‐matter correlations by splitting the underlying reality into aspects. In addition, it suggests induced, occasional, evasive mind‐matter correlations above and below, respectively, those stable baseline correlations. Two significant roles for the concept of meaning in this framework are elucidated. Finally, it is shown that the obtained typology is in perfect agreement with an empirically based classification of the phenomenology of mind‐matter correlations as observed in exceptional human experiences.     

顿悟与源事件中启发信息的激活

采用先学习源事件、后进行顿悟问题解决的两阶段实验范型,探讨了大学生解决九点四划问题的成功顿悟与源事件中所包含的启发信息提取之间的内在联系。结果发现,在顿悟问题解决阶段,只有激活学习阶段所获得的源事件中所包含的启发信息,才能成功解决顿悟问题。但并非所有激活源事件的被试都能成功解决九点四划问题,这取决于从源事件中所提取的启发信息的质量。研究结果还表明,内隐学习组与外显学习组正确解决九点问题的人数百分比差异并不显著,证明源事件中所包含的启发信息的激活,可能主要是自动加工的结果。     

顿悟问题解决的原型事件激活:自动还是控制

通过两个实验来考察四等分问题解决过程中原型事件及其启发信息的激活是自动加工还是控制加工。实验一的目的是考察原型学习量的增加是否会促进原型事件及其启发信息的自动激活,实验二的目的是考察提示对原型事件及其启发信息激活的影响。实验结果表明:原型事件及其所包含的启发信息的激活是顿悟的重要条件,原型的激活是自动加工的结果,而原型中所包含的启发信息的激活是控制加工的结果。     

CONSCIOUSNESS AND QUANTUM MECHANICS: OPTING FROM ALTERNATIVES

We present a model of a fundamental property of consciousness as the capacity of a system to opt among presented alternatives. Any system possessing this capacity is “conscious” in some degree, whether or not it has the higher capacity of reflecting on its opting. We argue that quantum systems, composed of microphysical particles, as studied by quantum mechanics, possess this quality in a protomental form. That is, such particles display the capacity to opt among alternatives, even though they lack the ability to experience or communicate their experiences. Human consciousness stands at the opposite end of the hierarchy of conscious life forms as the most sophisticated system of which we have direct acquaintance. We contend that it shares the common characteristic of a system capable of opting among alternatives. Because the fundamental property of consciousness is shared by human beings and the constituents of elementary matter in the universe, our model of consciousness can be considered as a modified form of panpsychism.     

论马克思的实践——社会生产关系本体论

For a long time, under the influence of traditional Western philosophy, Orthodox interpreters have distorted Marx’s philosophy as the ontology of matter, thereby concealing the essence of Marx’s philosophy, and eliminating the fundamental difference between Marx’s philosophy and traditional philosophy. This paper proposes that Marx’s philosophy is not the ontology of matter, but on the contrary, by examining the ontology of matter, Marx put forward his own ontological theory, i.e., the ontology of the praxis-relations of social production, by which Marx linked the realms of phenomenon and essence, revealing the content and essence of his philosophy. __________ Translated by Kong Hui from Zhexue yanjiu 哲学研究 (Philosophical Researches), 2008, (3): 3–11     

非言语学习不良的研究现状和展望

非言语学习不良日益成为学习不良研究的新热点,非言语学习不良的概念界定、筛查和诊断标准以及非言语学习不良的神经心理、认知、社会性和教育干预等领域取得了大量的研究成果。但是,非言语学习不良研究中还存在许多需要解决的问题,如：界定标准不统一;对非言语学习不良的系统研究有待完善;缺乏有效的干预模式及实证研究等。这些问题都需要进一步的研究、探讨     

White Matter Hyperintensities and Working Memory: An Explorative Study

ABSTRACT

White matter hyperintensities (WMH) are commonly observed in elderly people and may have the most profound effect on executive functions, including working memory. Surprisingly, the Digit Span backward, a frequently employed working memory task, reveals no association with WMH. In the present study, it was investigated whether more detailed analyses of WMH variables and study sample selection are important when establishing a possible relationship between the Digit Span backward and WMH. To accomplish this, the Digit Span backward and additional working memory tests, WMH subscores, and cardiovascular risk factors were examined. The results revealed that performance on the Digit Span backward test is unrelated to WMH, whereas a relationship between other working memory tests and WMH was confirmed. Furthermore, a division between several white matter regions seems important; hyperintensities in the frontal deep white matter regions were the strongest predictor of working memory performance.     

The rise of information in an evolutionary universe

This paper outlines the grand scenario of cosmic evolution by examining the ongoing changes among radiation, matter and life in standard, big‐bang cosmology. Using aspects of non‐equilibrium thermodynamics and information science, we argue that it is the contrasting temporal behavior of various energy densities that have given rise to the environments needed for the emergence of galaxies, stars, planets, and life forms. We furthermore argue that a necessary (though perhaps not sufficient) condition—a veritable prime mover—for the emergence of such ordered structures of growing complexity is the expansion of the Universe itself. Neither demon‐strably new science nor appeals to non‐science are needed to explain the impressive hierarchy of developmental change, from quark to quasar, from microbe to mind.