从系统论分析慢性炎症向肿瘤的恶性转化

慢性炎症相关肿瘤疾病,其机制涉及到的不再是个别的基因产物或蛋白分子,也不再是单一的信号通路或代谢途径,而是众多的基因、蛋白质和代谢小分子等各种生物分子构成的复杂的调控网络。这一网络中的相互联系、动态以及突变特性,要求运用系统论的方法来分析。这种分析将拓展临床医生的研究思路,推动对炎症向肿瘤转化本质的认识。     

连续性肾脏替代治疗临床应用的拓展与思考

连续性肾脏替代治疗（continuous renal replacement therapy, CRRT）是近30年来在透析技术基础上蓬勃发展起来的一种新的血液净化技术。CRRT最早应用于重症急性肾衰竭（acute renal failure,ARF）的治疗,随着人类对CRRT认识的不断深化和技术的不断发展,CRRT的...     

脾虚与胃黏膜损伤相关性的理论探讨

本文就脾虚与胃黏膜损伤的相关性从中医发病学、病机关联观、证型归纳属性及治法归类等4个方面,进行了理论探讨。认为中医脾虚的病理状态为胃黏膜损伤提供了客观条件,而胃黏膜损伤因素则又易加重脾虚证候,二者间存在着互为因果的相关关系。其观点为构建“从脾虚论治”胃黏膜损伤性疾病的治则观提供了理论基础。     

“上下意象图式”对汉语成语感情色彩加工的影响

通过两个实验,考察了＂上下意象图式＂对汉语成语感情色彩加工的影响。实验一发现,成语感情色彩加工存在＂隐喻一致效应＂,褒义的成语呈现在屏幕上方加工得更快,贬义的成语呈现在屏幕下方加工得更快、更准。实验二消除了具体空间信息的影响,发现仅有抽象符号水平的联结,＂上＂、＂下＂概念不能影响汉语成语感情色彩的加工。研究结果支持隐喻理论和具身认知观。     

时空距离、特征类型对态度的影响

建构水平理论（Construal level theory）认为时间能够独立地改变评价对象的建构水平,从而对对象的不同特征赋予不同的权重。个体倾向于用抽象的整体的特征表征时距远的事物,而用具体的局部的特征表征时距近的事物。空间距离不同的评价对象是否也遵循同样的规律？在考察时空距离与个人相关性的基础上,通过2（时间距离：明天和十年后）×2（空间距离：近地点和远地点）×2（特征类型：样例特征和类型特征）三因素被试间实验设计,探讨时间距离、空间距离、特征类型对态度的影响。结果发现,空间距离影响人们对事物的态度。在远空间距离水平上,时间距离对态度的影响显著,而在近空间距离水平上时间距离对态度的影响不显著;在远空间条件下,时距远的对象优先注意类型化的特征,时距近的对象优先注意样例化特征。最后,在建构水平理论框架内讨论了实验结果。     

坡度知觉及其影响因素的研究进展

人们对于地表斜坡的知觉是非常不准确的,通常表现为对坡度估计过高。但是,研究发现,在以行为的方式对坡度进行模拟时,所模拟的坡度值却与实际坡度基本一致。这种面对同一视觉线索出现的视知觉与行为不一致的现象即为坡度知觉中的“知觉-行为分离”。本文回顾了影响坡度知觉的各种因素,涉及视觉线索、认知判断、感觉通道、生理状态以及报告方式等方面的研究,并对坡度知觉的未来研究进行了展望。     

Are low‐literate and high‐literate consumers different? Applying resource‐matching theory to ad processing across literacy levels

This research investigates whether low-literate consumers process written advertisements differently than high-literate consumers do. Consistent with resource-matching theory (RMT), the first experiment reveals that, unlike high-literate processors, when low-literate processors read ads of moderate complexity, involvement with the ad does not affect processing. The second experiment extends RMT's applicability to both low- and high-literate consumers by demonstrating that low-literate processors' reading outcomes mirror those of high-literate processors when ads are written to reflect their reading capability.     

Dream rebound of suppressed emotional thoughts: the influence of cognitive load

Initial evidence suggests that suppressing a thought prior to sleep results in subsequent dreaming of that thought. The present research examined the influence of cognitive load on dreaming following suppression. In Experiment 1, 100 participants received either a suppression instruction or no instruction for an intrusive thought prior to sleep, and subsequently completed a dream diary. Participants instructed to suppress reported dreaming about the target thought more than controls; dream rebound was predicted by poorer performance on a working memory task. In Experiment 2, 126 participants received either a suppression instruction or no instruction for an intrusive thought prior to sleep, and half of participants also had cognitive load of learning a 9-digit number. Participants receiving the suppression instruction under cognitive load reported greater dream rebound than other participants. These findings indicate that thought suppression prior to sleep leads to dream rebound, and this effect is enhanced by cognitive load.     

Differential item functioning of the Rosenberg Self‐Esteem Scale in the US and China: Measurement bias matters

Using an item‐response theory‐based approach (i.e. likelihood ratio test with an iterative procedure), we examined the equivalence of the Rosenberg Self‐Esteem Scale (RSES) in a sample of US and Chinese college students. Results from the differential item functioning (DIF) analysis showed that the RSES was not fully equivalent at the item level, as well as at the scale level. The two cultural groups did not use the scale comparably, with the US students showing more extreme responses than the Chinese students. Moreover, we evaluated the practical impact of DIF and found that cultural differences in average self‐esteem scores disappeared after the DIF was taken into account. In the present study, we discuss the implications of our findings for cross‐cultural research and provide suggestions for future studies using the RSES in China.