基于脑结构像的精神分裂症机器学习分类

将机器学习应用于精神疾患的临床和基础研究是近年来的趋势。研究者将机器学习应用于精神分裂症患者及高危人群的T1加权像和弥散张量成像的脑影像数据中, 为了解疾病的生理病理学机制提供帮助。回顾以往研究发现额叶及颞叶的脑结构特征具有较高的区分能力, 行为数据和脑影像数据结合的分类效果优于单模态数据。现阶段研究存在样本量不足和泛化能力欠缺的局限, 未来研究应注意扩大样本量、制定标准化的分类方法, 从而进一步探究机器学习在精神疾患中的作用。     

社会建构主义心理学：“反实在论”还是“实在论”？

“反实在论”与“实在论”之争是当前有关社会建构主义心理学争论的核心。批判者指责社会建构主义心理学是“反实在论”,社会建构主义者则竭力澄清自己的“实在论”立场。该文认为：社会建构主义是一个芜杂的思想体系,任何一种简单的结论都难免失之武断,妨碍对它进一步的认识和理解;把握社会建构主义关键在于对“现实”的理解,社会建构主义的“现实”是统一了主客体的生活的现实,它对主客关系的超越对现代心理学具有重要的方法论意义;对于实在论者,了解实在论特有的问题和局限性,有助于更加理性地认识和参与这场争论。     

Choosing normative properties: a reply to Eklund’s Choosing Normative Concepts

ABSTRACT

The literature surrounding Horgan and Timmons’s Moral Twin Earth scenarios has focused on whether such scenarios present a metasemantic problem for naturalist realists. But in Choosing Normative Concepts, Eklund uses a similar scenario to illuminate a novel, distinctly metaphysical problem for normative realists of both naturalist and non-naturalist stripes. The problem is that it is not clear what (if anything) would suffice for the sort of ardent realist view that normative realists have in mind – the view that reality itself favors certain ways of acting and valuing. Eklund then offers a metasemantic view that he thinks can provide the best solution to this problem. In this reply to Eklund, I argue that Eklund’s treatment of the problem and his solution re-entangle metaphysical and metasemantic issues that ought to be kept separate. I also argue that there is a purely metaphysical solution to the problem at hand, which Eklund’s own solution seems to implicitly rely upon. While these criticisms do not suggest that Eklund’s positive view is false, they do undermine some of the broader lessons that Eklund hopes to draw from the view.     

To the Nothingnesses Themselves: Husserl’s Influence on Sartre’s Notion of Nothingness

In this article I argue that Sartre’s notions of nothingness and “negatity” are not, as he presents it, primarily reactions to Hegel and Heidegger. Instead, they are a reaction to an ongoing struggle with Husserl’s notion of intentionality and related notions. I do this by comparing the criticism aimed at Husserl in Sartre’s Being and Nothingness to that presented in his earlier work, The Imagination, where he discusses Husserl more elaborately. Furthermore, I compare his criticism to Husserl’s own criticism of the “doctrine of immanent objects”, in order to show that Sartre’s notion of nothingness is a continuation of Husserl’s criticism, and that he turns Husserl’s own arguments against himself.     

Adherence to pharmacological treatment of non-malignant chronic pain: The role of illness perceptions and medication beliefs

The objective was to identify the degree to which illness perceptions and medication beliefs explain variations in reported adherence to medication prescribed for the treatment of non-malignant chronic pain and to test the applicability of an extended version of the self-regulatory model to the chronic pain population. A cross-sectional design included 217 clinic patients completing validated questionnaires assessing their illness perceptions, medication beliefs and reported adherence to medication. Perceptions of illness (pain) as chronic, uncontrollable and unremitting were associated with greater adherence, fewer medication concerns and a belief that treatment was necessary. Structural equation modelling supports an extended SRM for chronic pain. It suggests that patients holding perceptions of serious consequences of pain and high emotion levels have more concerns about medication and are less adherent. Perceptions of serious illness consequences are also associated with stronger beliefs about the necessity of medicines and greater adherence. Beliefs about illness and medication are associated with adherence to treatment in chronic pain and this can be explained by an extended SRM. Results are preliminary and require replication. Further studies should explore the role that emotion has on coping strategies in chronic pain. Interventions should focus on altering unhelpful beliefs that reduce adherence.