Area-matching strategies used by young children

Across three studies, conditions were varied under which children aged 4–5 years matched the area of a rectangle with a given width (or height) to that of a square. In the first study, subjects observed the rectangle being changed in height from trial to trial and had access to their immediately preceding response. Under these conditions, rectangle width (the dimension under subject control) was a linear decreasing function of rectangle height. This function was interpreted as evidence for a hypothetical addition/subtraction strategy for maintaining equality in area between the comparison rectangle and the standard square. As a test of this hypothesis, in a second experiment the subjects were denied access to their immediately previous response, and in a third study they were also unable to observe the rectangle as it was altered by the experimenter between trials. The purpose of these changes was to remove the information necessary for readily implementing an addition/subtraction strategy. In both studies, area matches seemed to be based on a side-matching strategy, such that subjects matched one dimension of the rectangle to one side of the standard square. It was suggested that young children use different cues or strategies with different variants of the matching task because they do not possess a fixed, specific concept of area.     

Binocular disparity as a discriminable stimulus parameter for young infants

The ability of 8-week-old infants to discriminate between projected stereograms with and without retinal disparity was tested with an habituation-dishabituation paradigm. Infants in two experimental groups received six trials with either the disparity or the nondisparity stimulus and then were given two trials with the other display. Infants in two control groups viewed the same stimulus, either disparity or nondisparity, on all eight trials. There was a suggestion of some response decrement over time in both cardiac deceleration and sucking suppression, although this effect was not significant. However, significant increment was obtained on the dishabituation trials for heart rate in the group that was shifted from the nondisparity to the disparity stimulus. These results were interpreted as indicating that the infants could discriminate between stimuli when the only difference between them was binocular disparity.     

维生素D_3及其受体的临床意义

1,25-(OH)2D3是维生素D在体内发挥生理作用的活性形式。活性维生素D3通过与细胞内特异性维生素D受体结合,除了具有调节钙磷代谢的功能外,还发现其可预防和治疗骨质疏松、心血管疾病、自身免疫性疾病和一些肿瘤等。然而,维生素D缺乏在人群中非常普遍。