中心气道狭窄的诊断及介入治疗

中心气道狭窄可由多种原因引起。由于其部位在气管、隆突、左右主支气管及中间段支气管,因此可造成严重呼吸困难。近年来,围绕中心气道狭窄的处理,出现了很多介入治疗的方法,包括电刀、冷冻、氩气刀、激光、光动力、支架置入、球囊扩张及近距离照射等。如何合理应用这些技术是呼吸内科临床医生面临的一项重要课题。     

Argumentation Schemes in Persuasive Brochures

Many public information documents attempt to persuade the recipients that they should engage in or refrain from specific behaviour. This is based on the assumption that the recipient will decide about his or her behaviour on the basis of the information given and a rational evaluation of the pros and cons. An analysis of 20 public information brochures shows that the argumentation in persuasive brochures is often not marked as such. Argumentation is presented as factual information, and in many instances the task of making argumentational links and drawing conclusions is left to the reader. However, since the information offered does follow familiar argumentational schemes, readers can, in principle, reconstruct the argument. All the brochures make use of pragmatic argumentation (argumentation from consequences),i. e.,they formulate at least certain benefits of the desirable behaviour or disadvantages of the undesirable behaviour. In addition, they make regular use of argumentation from cause to effect and argumentation from example. Argumentation from rules and argumentation from authority are less frequently used. This empirical analysis of the use of argumentation schemes is a solid base for interesting and rich hypotheses about the cognitive processing of persuasive brochures. Central processing requires the reader to be able to reconstruct argumentation from informational texts and to identify and evaluate various types of argumentation.     

Visuo‐spatial abilities in autism: A review

Individuals with autism show various signs of heightened abilities in visuo‐spatial functioning. First, it is long‐established that they excel on embedded figures and block design tests relative to comparison participants. Second, some evidence suggests that processing global features is affected by inappropriate processing of the constituent elements of a stimulus. Third, they are more accurate than comparison participants in judging the shape of a slanted circle in a context in which ambient visual cues are eliminated. This suggests that their perception of the shape is less influenced by prior knowledge. Fourth, they are fast at searching for feature and conjunctive targets in a visual array. Contrary to earlier reports, however, they are susceptible to visual illusions. Also, they do show evidence of utilising prior knowledge when pairing a colour with an atypically coloured target. Accordingly, we conclude that there is something distinctive about autistic visuo‐spatial functioning, but not necessarily in ways that are predicted by the ‘weak central coherence’ hypothesis. Copyright © 2004 John Wiley & Sons, Ltd.     

中央重新定向对听觉返回抑制的影响

采用线索一靶子范式考察听觉中央重新定向对听觉返回抑制的影响。结果表明：1）听觉中央重新定向的有无不是听觉返回抑制产生的关键因素,但它的存在能够较好地引导听觉选择性注意进行快速转移,提高听觉选择性注意的搜索效率;2）听觉中央重新定向对听觉返回抑制量的大小没有显著影响。     

视、听双重记忆原序报告成绩下降的可能的原因

本文两种交替报告中的通道转移最多,但是都没有引起成绩大幅度下降。     

Rethinking the Divide: Modules and Central Systems

In this paper I argue that the cognitive system is best viewed as a continuum of cognitive processing from modules to central systems rather than having these as discrete and wholly different modes of cognitive processing. I rely on recent evidence on the development of theory of mind (ToM) abilities and the developmental disorder of autism. I then turn to the phenomenology of modular processes. I show that modular outputs have a stronger force than non-modular or central system outputs. I then evaluate social cognitions and show them to occupy a middle ground with respect to phenomenal strength between modular and non-modular outputs. The evidence presented then seems to indicate a continuum of cognitive processing rather than the traditional division between modules and central systems.

阈下语义启动效应影响因素述评

阈下语义启动效应是指阈下呈现的启动词能够对与之有语义联想关系的目标词的加工产生促进作用.阈下语义启动效应具有不稳定性且容易受到各种因素的影响.影响阈下语义启动效应的因素有外部因素和内部因素两大类,外部因素包括任务类型、实验材料和实验程序等因素,内部因素包括注意、任务设置、目的和期望.本文首先简单回顾阈下语义启动效应的研究历史,并介绍相应的研究范式及觉知状态的测量方法,然后重点对影响因素进行了总结和评述.未来的研究可以从优化研究范式、加强脑机制研究以及发展理论等几个方面进一步拓展.     

中枢肥大细胞在脑功能和行为调节中的作用

已知肥大细胞作为免疫细胞在过敏反应和炎性疾病中发挥重要作用。肥大细胞在中枢亦有表达, 但对其作用了解不足。新近的研究发现中枢肥大细胞在脑功能和行为调节中发挥重要的内源性平衡作用。一方面, 中枢肥大细胞在维持相关脑区发育, 正常神经活动, 以及动机, 情绪和认知等多种行为中发挥保护性作用, 各种应激条件诱导的中枢肥大细胞表达和活动改变参与脑和行为的适应性反应过程。另一方面, 中枢肥大细胞过度激活或者过度抑制都可导致脑功能和行为异常, 并参与某些免疫相关心身疾病的病理过程。体外神经解剖学和功能学研究证据提示中枢肥大细胞与神经系统间存在结构性和功能性相互作用网络。肥大细胞和神经组织间通过形成类似突触的结构性联系直接影响相邻细胞的活动。肥大细胞还可以通过脱颗粒释放多种生物活性介质调节神经活动, 同时表达多种受体接受脑内免疫性和神经性分子调节。但是目前对于中枢肥大细胞-神经系统相互作用的认识主要基于体外研究, 其在脑内相互作用方式及其与特定脑区功能和行为表型的关系所知甚少, 开展相关研究可以为认识脑与行为的神经免疫调节机制提供新的视角。     

内源性注意定向对立体视觉加工影响机制的ERP研究

本研究采用行为测量与ERP分析相结合的范式,以视差分离方式、线索提示有效性为自变量,考察三维空间中内源性注意定向对立体视觉加工的影响及其脑电机制。结果发现：无论是短SOA还是长SOA,3D空间中预测性中央符号线索对后续辨认任务均产生了启动效应,且启动效应量不随SOA延长而变化。短SOA下,经典提示效应和跨深度提示效应均表现为有效提示下的N1波幅大于无效提示条件;长SOA下,线索提示效应则表现出了无效提示条件诱发较大N1波幅的趋势。