Pubertal status associations with reward and threat sensitivities and subcortical brain volumes during adolescence

Adolescence is characterized by complex developmental processes that impact behavior, biology, and social functioning. Two such adolescence-specific processes are puberty and increases in reward sensitivity. Relations between these processes are poorly understood. The present study focused on examining unique effects of puberty, age, and sex on reward and threat sensitivities and volumes of subcortical brain structures relevant for reward/threat processing in a healthy sample of 9–18 year-olds. Unlike age, pubertal status had a significant unique positive relationship with reward sensitivity. In addition, there was a trend for adolescent females to exhibit higher threat sensitivity with more advanced pubertal development and higher reward and threat sensitivity with older age. Similarly, there were significant puberty by sex interaction effects on striatal volumes, i.e., left nucleus accumbens and right pallidum. The present pattern of results suggests that pubertal development, independent of chronological age, is uniquely associated with reward hypersensitivity and with structural differences in striatal regions implicated in reward processing.     

创造性思维与认知抑制的关系

抑制是创造性思维过程中的一种重要的认知加工机制。创造性思维与认知抑制的关系主要有三种观点：创造性思维的认知去抑制假说、认知抑制假说和适应性认知抑制假说。本文系统评述了创造性思维与认知抑制关系的相关理论、研究新进展和神经机制。未来研究应加强创造性思维与认知抑制关系的理论整合与构建,分析创造性思维的不同阶段的认知抑制机制,采用无意抑制与有意抑制研究范式,对创造性思维与认知抑制的关系、影响因素及神经机制进行深入研究。     

Maternal gestational stress alters adaptive and social behavior in adolescent rhesus monkey offspring

Data from rodent studies have indicated that stress experienced by pregnant mothers may result in behavioral and biological abnormalities in their offspring. However, few studies have examined the effects of prenatal stress on the offspring beyond the childhood period. In this study, 7 prenatally stressed (PNS) monkeys and 7 monkeys from undisturbed pregnancies were tested under mildly challenging conditions at 4 years of age. Following separation from cagemates and group formation, PNS monkeys showed more locomotion, abnormal and disturbance behavior than controls. Controls showed approximately six times more play than PNS animals. The PNS males showed the most clinging to others and the largest increase in contact with other animals over the period. Group differences were also found when the monkeys were observed as groups or alone in a playroom. Controls showed more explanatory behavior in the playroom, whereas PNS monkeys showed more inactivity. Control animals showed a decrease in distress vocalizations over time in the playroom, whereas PNS animals showed the opposite pattern. Control animals spent more time in proximity to and contact with cagemates than PNS animals. These results indicate that prenatal stress can have effects on adaptive and social behavior that persist into adolescence.     

Impulsivity and anxiety differences in cognitive inhibition

An identity negative priming task was employed to investigate cognitive inhibition in 245 undergraduates. The task presented consecutively a prime and a probe display that contained a target and a distractor. Negative priming is observed when subjects must respond to a target in the probe display that had been a distractor in the prime display. This task also served to study the Eriksen interference effect by comparing a condition in which the target and the distractor had the same identity with a condition in which they had different identities. Subjects completed the Sensitivity to Punishment and Sensitivity to Reward Questionnaire designed to measure Gray's anxiety and impulsivity dimensions. Results showed that impulsives had a lower cognitive inhibition than non-impulsives, whereas impulsive women also showed a greater Eriksen interference effect than non-impulsive women. Furthermore, no differences in task performance were found between anxious and non-anxious groups. Our discussion considers the importance of studying cognitive functioning in personality research.     

情绪对不同外倾水平个体行为抑制的影响

采用双选择oddball实验范式与事件相关电位（ERP）技术,探讨了情绪对行为抑制的影响以及外倾性的调节作用。行为数据发现,相比标准刺激,被试对偏差刺激的反应时显著更慢,证明实验成功诱发了行为抑制效应。在内倾组,负性刺激下偏差与标准刺激反应时差值显著长于正性刺激条件,而在外倾组无显著差异。脑电数据发现,在N2成分上,内倾组在正性情绪下的波幅显著小于负性和中性情绪,而在外倾组,不同情绪下的波幅不存在显著差异。在P3成分上,内倾组在正性情绪下的波幅显著大于负性和中性情绪,相反,外倾组在负性情绪下的波幅显著大于正性和中性情绪。结果表明,情绪对行为抑制的影响受到了个体外倾性水平的调节。     

线索有效性对儿童返回抑制的影响

采用通常的线索—靶子实验,来考察不同的线索有效性对儿童返回抑制的影响。所用的外源性线索分高有效性、低有效性和非信息性三类。儿童被试在实验中的任务为觉察圆形光点后即按键反应,记录反应时。结果表明,7岁、9岁和11岁儿童在高有效性和非信息性线索条件下均出现返回抑制;但7岁和9岁儿童在低有效性线索条件未出现返回抑制,而11岁儿童则出现。这些儿童的实验结果有别于成人。结果提示,7岁、9岁和11岁儿童的返回抑制是在外源性线索的作用下自动出现的,具有反射性质;但7岁和9岁儿童的返回抑制仍受线索有效性的制约,而11岁儿童返回抑制的发展已不受线索有效性的影响。     

执行功能与数量加工：回顾与展望

回顾了执行功能与数量加工之间的复杂关系。其中,执行功能的4个子系统——抑制、转换、刷新和双任务协调对数量加工的影响各不相同：抑制可以在一定程度上改变数量加工时的自动激活程度;转换功能则主要依赖注意来进行调节;刷新与数量加工关系的研究成果比较少;而双任务协调与数量加工之间的联系存在争论。文章最后分3个方面进行了研究趋势的展望,认为未来执行功能与数量加工的研究将突破相关研究的局限,通过更精巧的设计和大量特殊被试的研究取得突破性进展。     

The decline of aggressiveness in male mice during group caging as determined by punishment delivered by the cage mates

Group-housed rodents are generally less aggressive than isolated counterparts. The present study examined the role of defeat by cage mates as a reason for this decline in aggressiveness. In Experiment I, highly aggressive isolated male mice were introduced into aggressive or nonaggressive resident groups. The intruder's level of aggressiveness directed toward a group-housed standard opponent declined more rapidly after daily exposure to the aggressive than to the nonaggressive groups. Intruders in the aggressive groups received more attacks from their cage mates, and delivered fewer attacks to them than did the intruders in the nonaggressive groups. In Experiment II, the intruders lived for seven days in small wire net cages in the middle of the group cages. Their level of aggressiveness toward standard opponents decreased little during the preexposure but after being put freely into the groups, their aggressiveness declined to a minimal level within a day. Experiment III showed that when the wire net protection in the middle of the cage was installed after the group caging experience, the aggressiveness of the intruders did not return to the isolation level as effectively as it did in isolation. This is explained by the aggression-inhibiting content that the cues from the cage mates have acquired during group caging. The decline of aggressiveness in male mice during group caging is determined by punishment delivered by the cage mates.