Evidence for Free Radical-Mediated Reduction of Lymphocytic 5′-Ectonucleotidase During Stress

Previously we showed that stress and depression could result in a 50% lowering of lymphocytic 5-ectonucleotidase (NT) which could be resolved by a diet high in antioxidants. This study suggested that high levels of free radicals mediated by stress/depression may be involved in lowering NT activities. The aim of the present study was to assess whether oxygen radicals could directly affect NT and whether excess free radicals generated in stress/depression may affect tissue ascorbate stores. Exam-stressed students and depressed patients were compared respectively to these students at low stress and depressed patients on high antioxidant intakes. In this study, NT correlated positively with tissue ascorbate stores. A range of antioxidants were tested as possible inhibitors of oxy radical interaction with NT using nitroblue tetrazolium reduction to for-mazan with superoxide anion. At physiological plasma concentrations, ascorbate inhibited this reduction but dehydroascorbate, tocopherol, retinol, selenium, urate, and reduced glutathione were ineffective. Superoxide anion directly reduced lymphocytic NT activity and this effect was reversed by either 100 molar ascorbate in vitro or a high antioxidant intake in vivo. In conclusion, the low NT activities and ascorbate stores found in stressed/depressed people appear to be mediated by higher levels of free radicals reported in these subjects. These conclusions are consistent with published reports of (1) normal NT levels in melancholic patients on high antioxidant diets; (2) heightened inflammatory reponses during stress/depression; (3) low serum levels of zinc in depressed patients.     

Viewing exercise goal content through a person-oriented lens: A self-determination perspective

The present study examined profiles of exercise goal content and the associations with need satisfaction, motivation regulation and exercise behavior, combining variable-centered and person-centered analytical approaches. The participants were 1084 (279 men and 805 women) Swedish adults, aged between 18 and 78 years, that were all active members of an Internet-based exercise program. Latent profile analysis (LPA) and structural equation modeling (SEM) were used to analyze the data. In SEM analysis intrinsic goals were related to need satisfaction and autonomous motivation, whereas extrinsic goals were most strongly associated with controlled motivation. LPA revealed five unique latent classes of goal content. These five classes differed in need satisfaction, motivation regulation and exercise behavior, with classes being characterized by more intrinsic goal profiles reporting higher need satisfaction and autonomous motivation. The results are discussed from a self-determination theory perspective and the benefits of using both variable and person-centered analytical approaches are highlighted.     

TheOperational Code of John F. Kennedy During the Cuban Missile Crisis: A Comparison of Public and Private Rhetoric

This study examines the manner in which the Cuban missile crisis affected the belief system of President John F. Kennedy. The analysis uses data derived from primary source materials that have become available only in the last 2 years, in addition to well-known public statements by the president. The Verbs in Context System (VICS) was used to generate insights into how Kennedy's operational code differed across sources and changed during the period of the crisis. The results provide evidence of Kennedy's initial private belligerence and provisional support for the 'Gettysburg thesis' while calling into question some other potential interpretations of the effects of the crisis on the president's beliefs.     

从《论语》探析孔子素质教育思想的现代理论价值

人们普遍认为“素质教育”是一种新的教育模式,其实,早在两千多年前孔子就比较全面地提出了素质教育思想。《论语》正是孔子这一思想的集中体现。本文从教育对象、教育内容、教育方法诸方面总结孔子的素质教育思想,以利于深刻地理解素质教育的内涵,推进教育教学改革。     

Recognition hypermnesia: How to get it

Although recall hypermnesia (enhanced recall) over time with repeated testing has by now become an established empirical fact, its recognition counterpart, recognition hypermnesia, has defied clear-cut laboratory confirmation. In four studies, which relied on the retrieval component of recognition memory, it was shown that recognition memory, indexed by d′, reliably improved over three successive recognition tests. The stimuli consisted of 140 cartoons, each comprising a picture and a verbal caption. Recognition memory was tested on transforms or part-forms (parts) of the original stimulus material (pictures only, verbal paraphrases of the pictures, the latent content of the cartoons, or the combination of paraphrases and latent contents). The strongest effects were obtained when the originally presented cartoons were tested on their latent (deep semantic) contents. Recognition hypermnesia for part-forms or transforms of earlier presented stimuli has potentially wide-ranging implications since real-world recognition—of faces, texts, visual scenes—usually involves recognising stimuli that are variants, not exact copies, of the originally encountered materials.     

Jerry Fodor on non-conceptual content

Proponents of non-conceptual content have recruited it for various philosophical jobs. Some epistemologists have suggested that it may play the role of “the given” that Sellars is supposed to have exorcised from philosophy. Some philosophers of mind (e.g., Dretske) have suggested that it plays an important role in the project of naturalizing semantics as a kind of halfway between merely information bearing and possessing conceptual content. Here I will focus on a recent proposal by Jerry Fodor. In a recent paper he characterizes non-conceptual content in a particular way and argues that it is plausible that it plays an explanatory role in accounting for certain auditory and visual phenomena. So he thinks that there is reason to believe that there is non-conceptual content. On the other hand, Fodor thinks that non-conceptual content has a limited role. It occurs only in the very early stages of perceptual processing prior to conscious awareness. My paper is examines Fodor’s characterization of non-conceptual content and his claims for its explanatory importance. I also discuss if Fodor has made a case for limiting non-conceptual content to non-conscious, sub-personal mental states. This paper has grown out of comments I made on Fodor’s paper “Revenge of the Given,” delivered at The Steven Humphrey Excellence in Philosophy Conference: “Content and Concepts: A Conference on the Philosophy of Mind” at the University of California, Santa Barbara, February 14, 2004. Thanks to Jerry Fodor for useful feedback, and to Barry Loewer for discussing with me the ideas that went into this paper.     

Gerontological Counseling Trends in Adultspan Journal: 1999–2019

Using quantitative content analysis, we categorized 76 out of 154 articles (49.35%) published in Adultspan Journal from 1999 to 2019 as focused on gerontological counseling. This study explored publication trends for these articles and compared results with a larger study (Fullen et al., 2019) on publication trends for gerontological counseling across all counseling‐related journals.