妊娠合并结核临床诊治的决策

妊娠合并结核是一种对母婴健康危害极大的妊娠期疾病。在妊娠期结核病中,多数患者无明显症状,早期症状与妊娠期某些生理反应相似,加之妊娠与结核病的相互影响,x线、CT等重要的影像学检查受限,致使本病易被误诊或误治。某些抗结核药物对母婴的不良影响,使其治疗难以实施,由于结核病本身及治疗后可能对胎儿的影响,在临床上是否终止妊娠往往难以决策。本文就妊娠合并结核诊治过程中的相关问题进行综述,以期为临床诊治决策提供帮助。     

The Relation of ERP Components to Complex Memory Processing

The relation between various ERP components generated during encoding of a word and its subsequent recall were investigated using a “rote” serial-order and an “elaborative” category memory task. Words (flashed separately) were time-locked to EEG recordings from 21 cortical sites. ERP components from the five subjects having the highest recall scores were compared to the five lowest scoring subjects. Results based on the P200 peak amplitude data as well as the N400 and late positive component peak amplitude and latency data suggest that anterior and posterior distributional differences are elicited during encoding of words for rote and elaborative memory tasks. Furthermore, strong individual differences in these patterns were found as a function of task. A tentative argument was made that the obtained anterior and posterior differences may index different word feature selection and encoding processes, which are differentially utilized by high and low recallers.     

Stereotype activation is unintentional: Behavioural and event‐related potenials evidence

In this study, a priming Stroop paradigm was used to determine whether stereotype activation is unintentional. Priming conditions (priming/no‐priming) and the relationship between priming and target (consistent/inconsistent/no‐relation) were the independent variables; accuracy, reaction time and N400 amplitude were used as dependent variables. The reaction time revealed that stereotype activation is, to some extent, unintentional. Furthermore, the event‐related potenial (ERP) results showed that N400 amplitude was larger for inconsistent conditions than for consistent conditions. This result supported the notion that stereotype activation is an unintentional and automatic process.     

Counterintuitive Religious Ideas and Metaphoric Thinking: An Event‐Related Brain Potential Study

It has been shown that counterintuitive ideas from mythological and religious texts are more acceptable than other (non‐religious) world knowledge violations. In the present experiment we explored whether this relates to the way they are interpreted (literal vs. metaphorical). Participants were presented with verification questions that referred to either the literal or a metaphorical meaning of the sentence previously read (counterintuitive religious, counterintuitive non‐religious and intuitive), in a block‐wise design. Both behavioral and electrophysiological results converged. At variance to the literal interpretation of the sentences, the induced metaphorical interpretation specifically facilitated the integration (N400 amplitude decrease) of religious counterintuitions, whereas the semantic processing of non‐religious counterintuitions was not affected by the interpretation mode. We suggest that religious ideas tend to operate like other instances of figurative language, such as metaphors, facilitating their acceptability despite their counterintuitive nature.     

语篇语境对句子理解的影响：来自N400的证据

N400作为语义违反的特异性ERP组分,其波幅反映了语义整合加工过程的难度,因此可将其作为研究语篇语境意义建构过程的一项重要指标。语篇语境可分为语言语境和非语言语境。前人一系列基于语篇水平的N400研究表明,从语义的角度上看,语言语境对句子理解具有制约和协调作用,其机制涉及词汇语义启动、场景适宜性、文字内容信息以及因果推理等方面;非语言语境对句子理解具有制约和补充作用,但其机制尚不明确。两种不同来源的语义信息在实时理解中是同时得到加工的     

双语即时切换下非目标语言语音和语义的激活状态

本研究采用双语即时切换范式, 探讨非熟练中英双语者在对目标语言(启动词)语音或语义的加工过程中非目标语言的激活状态。实验1设置了与启动词的翻译对等词存在语音相关或无关的两类配对词, 要求被试进行语音判断任务, 结果表明, 不论哪种切换条件, 两类配对词在反应时和P200成分上都没有差异, 说明目标语言在语音加工过程中非目标语言的语音层面没有得到自动激活, 从而没有产生启动效应。实验2则设置了语义相关和无关配对词, 并进行语义判断任务, 结果在两种切换条件下都发现明显的语义启动效应及N400差异, 说明非目标语言在语义层面上有得到自动激活, 但激活的程度表现出切换方向上的不一致, L1-L2切换下的语义启动量要明显大于L2-L1, 并且L1-L2的N400差异主要表现在前部脑区, 持续时间更久, 而L2-L1的N400差异主要表现在后部脑区, 但持续时间较短, 表明对于非熟练的双语者来说, 不同切换方向下对共享语义表征的激活加工是不一样的。     

任务与字频对汉字情绪启动反转效应的影响

本研究使用ERP技术对比了效价判断与真假字判断两种任务形式下的汉字情绪启动效应。结果发现,在效价判断任务中高频目标字出现情绪启动的反转效应,效价不一致比一致条件下反应时短,诱发了较大的P200;低频目标字出现情绪启动的一致性效应,效价一致比不一致条件下反应时短,诱发了较大的P200与N400。真假字判断任务中高频和低频目标字均出现情绪启动的一致性效应。情绪启动的反转效应依赖于刺激材料的可通达性与注意导向,启动字与目标字的反应竞争关系导致了情绪启动的反转效应。     

甲型H1N1流感大流行2周年记

2009年4月,墨西哥暴发甲型H1N1流感疫情,并迅速蔓延至全球。2009年6月11日,世界卫生组织宣布进入流感大流行,直到2010年8月10日世卫组织宣布世界步入流感大流行后期。自流感暴发已经2年过去了,回顾整个过程我们从中可以学到许多经验和教训,并随时准备应对将来可能发生的新的流感疫情。     

生长激素对心血管系统的影响

生长激素（GH）是出生后主要刺激生长的激素,GH相当高比例的促生长作用是由胰岛素样生长因子-I（IGF—I）介导完成的。不同的代谢功能如碳水化合物和脂类代谢也受GH的直接影响。GH还对心血管及大脑有影响,本文拟对其分泌机制及作用和对心血管及大脑的影响作一综述。     

2009年-2011年广州市甲型H1N1流感监测定量研究

本文对广州市2009年7月～2011年1月的发热呼吸道监测数据进行了定量分析,并在此分析的基础上提出了相关政策建议,比如加强人群分类管理、加快疫苗研制、避免抗病毒药物的滥用、重视健康管理和健康教育以及遵循预防控制原则等。