高尿酸血症与急性脑梗死患者病情严重程度和预后的相关性研究

文章探讨高尿酸血症与急性脑梗死患者病情严重程度和预后的相关性.选择急性脑梗死患者198例,男性115例,女性83例,以前瞻性病例对照的研究方法,分析高尿酸血症与急性脑梗死患者入院时、住院10天时的病情严重程度和90天预后的相关性.高尿酸血症与急性脑梗死患者入院时病情严重程度无关（P＆gt;0.05）,与住院10天时病情严重程度呈负相关（P=0.003）,与10天时的美国国立卫生研究院卒中量表（NIHSS）转归分数呈正相关（P=0.002）,与90天预后呈正相关（P=0.001）.笔者认为高尿酸血症与急性脑梗死患者住院10天时的病情严重程度和90天预后具有独立的相关性.     

正念减压疗法在护士职业倦怠干预中的应用

在当前的医疗和社会环境下,护士群体面临着巨大的压力,承受着职业枯竭困扰。针对国内护士职业倦怠干预研究的现状,着重介绍了西方临床心理学界广泛应用的正念减压疗法(mindfulness-based stress reduction,MBSR)及其在压力管理和身心疾病的康复等方面的积极疗效。根据正念减压疗法的特点、作用机制和其与护理理论的关系,探讨这种训练应用于护士职业倦怠预防和干预的合理性。     

Context and Complexity in Incremental Sentence Interpretation: An ERP Study on Temporal Quantification

The present event-related potential (ERP) study used picture–sentence verification to investigate the neurolinguistic correlates of the online processing of compositional-semantic information. To this end, we examined context effects on sentences involving temporal adverbial quantification likeJana war jeden Morgen schwimmen an den Arbeitstagen (“Jana went for a swim every morning during the working week”). We tested whether the conceptual complexity associated with quantifying over time intervals leads to delayed predictions regarding the upcoming words in a sentence. The present study replicated previous results relating to quantification over individuals, which are conceptually less complex than time intervals. Analogous to previous studies, false vs. true sentences elicited an N400 whenever contextual cues did not permit a potential revision of a locally assigned truth value. The present results are compatible with an approach under which contextual cues are immediately considered for predicting how a sentence continues. The fact that the contextual complexity did not lead to processing delays indicates that the processing system quickly abstracts away from the conceptual complexity associated with the linguistic input if such an abstraction is possible.     

汉英语言内及语言间重复启动效应的ERP研究

16名母语为汉语的被试参加了一个混合语言的语义判断任务,关键词用汉语和英语呈现,然后重复这些词（语言内或者语言间）。比较词汇第一次呈现、语言内和语言间重复产生的N400波幅的差异发现：汉语和英语的语言内重复启动效应差异不显著,而两种方向的语言间重复启动效应存在不对称性,从英语到汉语的重复启动效应显著大于从汉语到英语的重复启动效应,这与双语表征的非对称模型不尽一致。     

Career choice and orality

The field of vocational psychology is replete with schemata for the determinants of career choice in adulthood (e.g., A. Roe, The psychology of occupations. New York: Wiley, 1956; D. E. Super, The psychology of careers. New York: Harper &Row, 1957; J. O. Crites, Vocational psychology: The study of vocational behavior and development. New York: McGraw-Hill, 1969). A view not given much weight in empirical research in this area is that of psychoanalytic theory relating career choice to unresolved childhood conflicts and their derivatives. To examine the validity of this psychoanalytic prediction, students' Rorschach protocols were analyzed to yield an index of frustrated oral needs. The students were given decks of careers to rank from most to least preferable. Results showed that the ranking of the oral careers was a function of the Rorschach index of frustrated oral needs for women only but not for men.     

LP方法及其与三种常用DIF检测方法的比较

本研究基于项目反应理论,提出了一种检验力高且犯Ⅰ类错误率小的检测DIF的新方法：LP法（Likelihood Procedure）,且以2PLM下对题目进行DIF检验为例介绍此法。本文通过与MH方法、Lord卡方检验法和Raju面积测量法三种常用的检验DIF的方法比较研究LP法的有效性,同时探讨样本容量、测验长度、目标组和参照组能力分布的差异、DIF值大小等相关因素对LP法有效性可能产生的影响。通过模拟研究,得到以下结论：(1)LP法比MH法及Lord卡方法更灵敏且更稳健;(2) LP法比Raju面积测量法更合理;(3)LP法的检验力随着被试样本容量或DIF值的增大而增大;（4）当参照组与目标组的能力无差异时,LP法在各种条件下的检验力比参照组与目标组的能力有差异时的检验力高;（5）LP法对一致性DIF和非一致性DIF都有良好的检验力,且LP法对一致性DIF的检验力比对非一致性DIF的检验力高。LP法可以简便的扩展并运用到多维度、多级评分项目上。     

汉字识别中字形畸变和语境的ERP效应

以事件相关电位（ERP）技术和语义启动范式,采用同一字判断（靶字延迟反应）作业,考察字形畸变和语境对低频汉字识别的影响。结果发现,无语义启动时,畸变靶字正确率低于清晰靶字;启动效应只体现在畸变时的正确率上。150–300ms窗口,畸变字比清晰字诱发峰值更负的N170;300–500ms时间窗口,不启动条件诱发平均波幅更负的N400,畸变字诱发更大N400。结论是,畸变字诱发的N170成分,在一定程度上反映了字形加工;N400的语义启动效应和畸变效应,扩展Holcomb的研究,并支持语义提取理论。     

高度模糊靶字下的N400语义启动效应：词汇加工理论的证据

本研究基于不可识别模糊字词仍能诱发N400的词汇加工理论的假设,让被试对模糊字进行同一字延迟判断,利用脑电技术记录不同模糊程度靶字的认知过程,来探讨N400出现的条件,以阐明N400反映的是词汇加工,还是词汇后加工。实验结果表明：与可识别、轻度模糊汉字一样,不可识别、高度模糊汉字仍然可以诱发N400;这种N400语义启动效应反映了词汇加工过程。     

慢性乙肝治疗路线图和HBV DNA、HBeAg、HBsAg定量的监测意义

慢性乙型肝炎病毒感染呈世界分布并且引起不良结局,是极为严重的健康问题。慢性乙型肝炎治疗最重要的目标是长期抑制病毒以改善预后,防止出现肝硬化、肝衰竭和肝癌。目前,抗病毒药物主要有干扰素和口服核苷（酸）类似物,核苷（酸）类似物的缺点主要在于长期治疗中出现耐药。路线图概念被用于监测耐药预测疗效。HBV DNA定量水平被作为路线图较好的监测指标。由于血清转换率及清除率过低,HBeAg、HBsAg定量检测不适合用于路线图监测,但对于使用聚乙二醇干扰素的慢性乙肝患者,可作为预测治疗应答的指标。     

脑梗死不同病因亚型同血浆同型半胱氨酸浓度的关系研究

为探讨脑梗死患者血浆同型半胱氨酸（HCY）水平同病因分型及疾病严重程度的关系,选择首发脑梗死急性期患者73例,对照组30例,进行TOAST病因分型、NIHSS神经功能缺损评分、血浆HCY检测。结果显示,病例组血浆HCY升高率、水平比对照组显著增高;大动脉粥样硬化亚型病例组血浆HCY水平比对照组明显增高;病例组血浆HCY水平同NIHSS评分呈正相关,提示高HCY血症是脑梗死发病及大动脉粥样硬化亚型脑梗死发病的高危因素,血浆HCY水平同神经功能缺损程度正相关。