知识整合的时间进程：ERP研究

本研究借助ERP技术,采用分离句子范式,考察了被试通过整合主干事实生成新知识的时间进程。结果发现：（1）知识整合事实相对于传递性推理事实和新颖事实诱发了更小的N400,与众所周知事实没有显著差异,表明通过整合生成的新信息已经快速纳入了语义知识库;（2）对比两次呈现,延迟性整合事实在第二次呈现的350ms之后波幅显著下降,与众所周知事实没有显著差异,表明知识经验影响了整合的时间进程,相较两个新信息之间的即时整合,新旧信息之间的延迟整合需要更多的时间。     

汉字正字法家族效应的ERP研究

以汉字为实验材料,自变量为汉字正字法笔画家族大小,采用延迟反应的同一字判断任务,记录并研究大学生被试对刺激字的脑电(EEG)。本文对笔画家族的定义是,通过改变1~5笔笔画得到刺激字的正字法家族成员,改变的笔画不构成部件。脑电结果显示:大家族刺激字比小家族刺激字诱发更负的N400和N250成分、更低的P200,其中N400的结果与基于交互激活模型的二阶段理论的预期一致。     

An intentional stance modulates the integration of gesture and speech during comprehension

The present study investigates whether knowledge about the intentional relationship between gesture and speech influences controlled processes when integrating the two modalities at comprehension. Thirty-five adults watched short videos of gesture and speech that conveyed semantically congruous and incongruous information. In half of the videos, participants were told that the two modalities were intentionally coupled (i.e., produced by the same communicator), and in the other half, they were told that the two modalities were not intentionally coupled (i.e., produced by different communicators). When participants knew that the same communicator produced the speech and gesture, there was a larger bi-lateral frontal and central N400 effect to words that were semantically incongruous versus congruous with gesture. However, when participants knew that different communicators produced the speech and gesture--that is, when gesture and speech were not intentionally meant to go together--the N400 effect was present only in right-hemisphere frontal regions. The results demonstrate that pragmatic knowledge about the intentional relationship between gesture and speech modulates controlled neural processes during the integration of the two modalities.     

Violations of information structure: an electrophysiological study of answers to wh-questions

This study investigates brain responses to violations of information structure in wh-question-answer pairs, with particular emphasis on violations of focus assignment in it-clefts (It was the queen that silenced the banker). Two types of ERP responses in answers to wh-questions were found. First, all words in the focus-marking (cleft) position elicited a large positivity (P3b) characteristic of sentence-final constituents, as did the final words of these sentences, which suggests that focused elements may trigger integration effects like those seen at sentence end. Second, the focusing of an inappropriate referent elicited a smaller, N400-like effect. The results show that comprehenders actively use structural focus cues and discourse-level restrictions during online sentence processing. These results, based on visual stimuli, were different from the brain response to auditory focus violations indicated by pitch-accent [Hruska, C., Steinhauer, K., Alter, K., & Steube, A. (2000). ERP effects of sentence accents and violations of the information structure. In Poster presented at the 13th annual CUNY conference on human sentence processing, San Diego, CA.], but similar to brain responses to newly introduced discourse referents [Bornkessel, I., Schlesewsky, M., & Friederici, A. (2003). Contextual information modulated initial processes of syntactic integration: the role of inter- versus intrasentential predictions. Journal of Experimental Psychology: Learning, Memory and Cognition, 29, 871-882.].     

Brain responses to lexical-semantic priming in children at-risk for dyslexia

Deviances in early event-related potential (ERP) components reflecting auditory and phonological processing are well-documented in children at familial risk for dyslexia. However, little is known about brain responses which index processing in other linguistic domains such as lexicon, semantics and syntax in this group. The present study investigated effects of lexical-semantic priming in 20- and 24-month-olds at-risk for dyslexia and typically developing controls in two ERP experiments. In both experiments an early component assumed to reflect facilitated lexical processing for primed words was enhanced in the at-risk group compared to the control group. Moreover, an N400-like response which was prominent in the control group was attenuated or absent in at-risk children. Results suggest that deficiencies in young children at-risk for dyslexia are not restricted to perceptual and lower-level phonological abilities, but also affect higher order linguistic skills such as lexical and semantic processing.     

脑电双频指数（BIS）对脊柱侧凸矫正术中唤醒时间的影响

探讨脑电双频指数（bispectral index,BIS）监测不同镇静深度对脊柱侧凸矫正术中唤醒时间的影响,60例行脊柱侧凸矫正手术的患者随机分为三组,Ⅰ组BIS30～40,Ⅱ组BIS40～50和Ⅲ组BIS50～60,评价各组患者的唤醒时间及不良事件发生率。结果显示Ⅰ组唤醒时间为（18．13±2．3）min,明显长于Ⅱ组和Ⅲ组的唤醒时间。而当BIS为40～50时,患者术中的不良事件发生率明显低于另外两组。所以,使用BIS进行全麻镇静深度的监测,在唤醒前将镇静深度维持在BIS40～50是合适的。     

关于甲型H1N1流感未来流行趋势的几点分析

2009年3月以来出现的甲型H1N1流感是一种全新的流感病毒,目前已在全球大流行.从半年的疫情监测结果判断,轻症患者居多,病毒似乎还没有产生明显的变异。但随着北半球冬季的到来,患者数目必然急剧增多。由于现有的疫苗不能充分满足需要,医疗和防疫部门仍需承担相当艰巨的任务。     

内隐联想测验研究进展述评

内隐联想测验作为基于反应时范式的内隐社会认知研究方法,自1998年由Greenwald提出后,得到了广泛的应用。但因其本身具有一定局限性,近10年来,研究者们对这一方法进行了不断地修正和改进,先后发展出了GO／NO—GO联想任务、外部情感西蒙作业等;近几年又提出了单类内隐联想测验、单靶内隐联想测验和单属性内隐联想测验等,这些方法丰富充实了内隐联想测验,是对Greenwald提出的IAT的继承和发展。     

声乐与器乐情绪加工的ERP研究

借助跨通道情绪启动范式考察声乐与器乐情绪加工的电生理差异。启动刺激是声乐和器乐曲(小提琴演奏), 目标刺激是与音乐情绪一致或不一致的面孔表情图片。结果显示, 与一致条件相比, 与面孔情绪不一致的器乐曲诱发了N400, 而与面孔情绪不一致的声乐曲诱发了LPC。这些结果表明, 声乐与器乐情绪加工的电生理反应存在差异。     

On the early left-anterior negativity (ELAN) in syntax studies

Within the framework of Friederici’s (2002) neurocognitive model of sentence processing, the early left anterior negativity (ELAN) in event-related potentials (ERPs) has been claimed to be a brain marker of syntactic first-pass parsing. As ELAN components seem to be exclusively elicited by word category violations (phrase structure violations), they have been taken as strong empirical support for syntax-first models of sentence processing and have gained considerable impact on psycholinguistic theory in a variety of domains. The present article reviews relevant ELAN studies and raises a number of serious issues concerning the reliability and validity of the findings. We also discuss how baseline problems and contextual factors can contribute to early ERP effects in studies examining word category violations. We conclude that - despite the apparent wealth of ELAN data - the functional significance of these findings remains largely unclear. The present paper does not claim to have falsified the existence of ELANs or syntax-related early frontal negativities. However, by separating facts from myths, the paper attempts to make a constructive contribution to how future ERP research in the area of syntax processing may better advance our understanding of online sentence comprehension.