Plus de contention ni d’isolement sans contrôle du juge judiciaire

Although of old and common use, the use of isolation and restraint in psychiatry was not regulated until 2016 with the creation of article L. 3222-5-1 of the Public Health Code. However, the Court of Cassation considered that, as a form of care, it was beyond the office of the liberty and custody judge to controle its implementation. Questioned by a plea of unconstitutionality submitted by the Court of Cassation, the Constitutional Council considered, with its decision of 19 June 2020, that these measures constituted a deprivation of liberty requiring judicial review at short notice. The Sages thus declare the provisions of article L. 3222-5-1 unconstitutional, with delayed effect as of December 31, 2020, requiring legislator to rethink and organise the supervision and control of decisions of restraint and isolation.     

Le vaccin,un médicament devenu l’arme absolue promise contre la COVID-19 : une réglementation adaptée ?

As the first vaccines against COVID-19 arrive on the market, the question of the safety of these products arises in the public debate. The major concern is about the possible occurrence of adverse effects, particularly in the context of the use of novel pharmaceutical technologies such as mRNA. It is important to remind both patients and professionals that a vaccine is not only a medicinal product in its own right, but also a special medicinal product: biological and immunological. As a result, its supervision is draconian, and despite the urgency, no requirements have been lowered. The speed of marketing is the result both of adapted clinical trials and optimized evaluation procedures.     

γ节律神经振荡：反映自闭症多感觉整合失调的一项重要生物指标

多感觉整合是对不同感官信息进行选择、联系、统一乃至解释的加工过程, 它需要神经系统不同功能区域的共同投入与相互协调, 以实现多种感觉信息的时间捆绑以及全局性的预测编码。而γ神经振荡因具有反映神经皮层兴奋/抑制的平衡状况, 实现多感官信息的时间同步, 以及通过跨频耦合实现全局性预测编码的特点, 在多感觉整合的加工过程中发挥着重要作用。相比正常个体, 自闭症患者神经系统中的GABA中间神经元存在结构与功能异常, 导致γ神经振荡紊乱, 由此破坏了正常的时间同步以及预测编码加工, 并最终引发多感觉整合失调。基于上述因果关联, 未来研究可结合无创可逆性干预技术, 以γ节律神经振荡为生物反馈指标, 形成科学系统化的临床干预治疗方案。     

创造力产生过程中的神经振荡机制

创造力究竟是怎么产生的, 目前尚未得出一致的结论。神经电生理技术因其高时间分辨率, 可以准确地揭示创造力产生进程中的神经振荡机制, 从而帮助人们更深刻地理解创造力的本质。近年来的研究发现, 单节律alpha神经振荡会随着创造力的增加而增强, 这反映了创造力产生过程中的内部信息加工需求增加、自上而下的抑制控制增强。同时, 多频段神经振荡交叉节律耦合体现了创造性产生过程中额叶、颞叶和顶叶等多脑区之间信息交流的动态变化。未来研究应该以整合理论框架为基础, 结合多层次多方法的研究工具, 引进更生态化的数理计算方法, 并利用计算神经科学建模来预测个体创造力发展趋势, 从而全面深刻地认识创造力的本质。     

中国人限制性饮食和食物渴求的认知神经机制

物质丰富的时代, 如何抵御美味食物线索带来的食物渴求, 并限制饮食从而保持健康成为人们关注的重要话题之一。近年来, 国内学者为了探讨节食成功的原因, 创建中国食物图片库, 考察限制性饮食的认知神经机制, 以及成功和失败限制性饮食者的脑机制差异; 开展了特质食物渴求及中国特色的辣食渴求的认知神经研究。对推进饮食行为研究的理论发展, 也为肥胖、饮食失调等健康干预工作提供重要支持。     

动作视频游戏对发展性阅读障碍者阅读技能的影响及其内在机制

发展性阅读障碍是一种在获得阅读技能方面的特殊困难, 这种障碍会严重影响个体的发展, 如何帮助发展性阅读障碍者改善其阅读技能是近年来研究的焦点。传统的干预方法主要针对发展性阅读障碍者的语音缺陷, 这类方法存在一些问题, 如费时费力、给阅读障碍者带来阅读压力等。近年来, 大部分研究表明通过趣味性的动作视频游戏训练可以显著地提高发展性阅读障碍者的阅读技能, 但是其背后的机制尚不明确。基于大细胞通路缺陷理论框架, 从视觉空间注意、注意跨通道转换、视觉运动加工等方面来梳理动作视频游戏与阅读之间的关系, 揭示了动作视频游戏训练对阅读效率影响的可能内在机制。未来的研究可以在大细胞通路缺陷理论的框架下, 深入分析动作视频游戏改善阅读的神经机制, 并尝试开发更适合发展性阅读障碍者的干预程序。     

贝叶斯决策理论对复杂运动决策中运动预期的启发——以网球和足球为例

对运动决策的研究是认知运动心理学的一个重要领域。运动预期被认为是运动决策的核心, 受到运动学和非运动学信息的影响。其中, 对运动预期研究的一个关键问题是探讨不同信息源对运动结果预期的贡献以及两者之间的相互作用。研究者运用贝叶斯决策理论解释运动预期中不同信息的整合过程, 分析运动员在复杂的竞赛情景中如何做出最佳决策, 尤其是对该理论在网球和足球领域的潜在应用进行分析。在不确定的情况下, 竞技体育中并非所有的选择、结果或概率都是已知的, 故有研究者认为概率论和经典的决策理论不能有效解决此类问题。然而新近提出的启发式近似, 为运动员在贝叶斯框架下如何快速做出选择提供了理论依据：首先, 在复杂和有时间压力的竞赛情景中, 启发式近似假设运动员依据竞赛中不同信息源的不确定程度, 很可能选择在运动学信息和情境先验之间进行切换启发式, 提高运动预期的效率。其次, 判断效用通过卷积效应影响两种信息源的整合, 降低情境先验的影响程度。     

幼儿在联合行动中共同表征能力的发展

为探究幼儿联合行动共同表征能力的发展,实验1通过比较186名3~5岁幼儿在相同任务和不同任务的表现,发现4岁和5岁幼儿在不同任务中的表现比相同任务差;实验2进一步验证幼儿在不同任务中较差的表现源于对自我和同伴的共同表征。结论：3岁幼儿无法在联合任务中同时表征自我和同伴,没有表现出明显的共同表征能力,4岁以上幼儿开始具备稳定的共同表征能力,能够在联合任务中同时表征自己和同伴,由此对自己的行为表现造成干扰。     

Generating interior search directions for multiobjective linear programming

A new multiobjective linear programming (MOLP) algorithm is presented. The algorithm uses a variant of Karmarkar's interior-point algorithm known as the affine-scaling primal algorithm. Using this single-objective algorithm, interior search directions are generated and used to provide an approximation to the gradient of the (implicitly known) utility function. The approximation is guided by assessing locally relevant preference information for the various interior directions through interaction with a decision maker (DM). The resulting algorithm is an interactive approach that makes its progress towards the solution through the interior of the constraints polytope.     

Aging Affects the Ability to Process the Optic Flow Stimulations: A Functional Near-Infrared Spectrometry Study

Abstract

Optic flow (OF) has been utilized to investigate the sensory integration of visual stimuli during postural control. It is little known how the OF speed affects the aging brain during the sensory integration process of postural control. This study was to examine the effect of OF speeds on the brain activation using functional near-infrared spectroscopy (fNIRS) and postural sway between younger and older adults. Eleven healthy younger adults (5M/6F, age 22?±?1-year-old) and ten healthy older adults (4M/6F, age 71?±?5-year-old) participated in this study. A virtual reality headset was used to provide the OF stimulus at different speeds. A forceplate was used to record the center-of-pressure to compute the amplitude of postural sway (peak-to-peak). Compared with younger adults, older adults showed significantly increased activation in the OF speed of 10?m/s and decreased activation in the OF speed of 20?m/s in the left dorsolateral prefrontal cortex. Older adults also showed decreased activation in the left temporoparietal region (VEST) in the OF speed of 20?m/s. A significant difference in peak-to-peak was found between groups. Our results indicated that age might be associated with the ability to process fast OF stimulation.