Effects of Temporal Lobe Lesions on Retrograde Memory: A Critical Review

Scientific interest in retrograde memory has grown considerably over the last two decades. Studies have demonstrated that several brain regions, including the temporal lobes, participate in the formation, maintenance and storage of past memories. Different patterns and extents of retrograde memory deficits have been recorded in patients with temporal lobe lesions. It has been argued that the pattern of retrograde memory deficits is determined not only by the side and specific location of lesion within this region, but also by methodology, medical variables (such as etiology or seizure history), and coexisting cognitive deficits. In this paper we will review published case and group studies of patients with temporal lobe lesions to evaluate the impact of these factors on retrograde memory.     

Prototype awareness enhancing and monitoring device for trichotillomania

Trichotillomania is an impairing condition that involves repetitive hair pulling. Habit reversal therapy is helpful for many persons with this disorder. Unfortunately, habit reversal therapy is not helpful for everyone and maintenance of gains is often problematic. Successful habit reversal therapy requires the individual to be aware of hair pulling and handling. Unfortunately, most people with trichotillomania report that much of their plucking occurs outside of awareness. Monitoring of trichotillomania behaviors is also problematic. The present project involved a pilot study of a prototype awareness enhancing and monitoring device aimed at increasing the effectiveness of habit reversal therapy. The device included a watch, bracelet, magnetic necklace, and a pager that was hard-wired for remote activation of a vibrating alert when hair pulling behaviors occurred. Following structured diagnostic assessment, three female participants were randomly assigned to be initially observed for varied lengths of time without the device followed by observation with the device in place. The results indicated a marked reduction in trichotillomania behaviors when the device was in place. Semi-structured interviews revealed that the device was very effective in enhancing awareness and monitoring of trichotillomania related behaviors and enthusiastic acceptance of the device was provided by all participants.     

Dynamic binding of identity and location information: a serial model of multiple identity tracking

Tracking of multiple moving objects is commonly assumed to be carried out by a fixed-capacity parallel mechanism. The present study proposes a serial model (MOMIT) to explain performance accuracy in the maintenance of multiple moving objects with distinct identities. A serial refresh mechanism is postulated, which makes recourse to continuous attention switching, a capacity-limited episodic buffer for identity-location bindings, indexed location information stored in the visuospatial short-term memory, and an active role of long-term memory. As identity-location bindings are refreshed serially, a location error is inherent for all other targets except the focally attended one. The magnitude of this location error is a key factor in predicting tracking accuracy. MOMIT’s predictions were supported by the data of five experiments: performance accuracy decreased as a function of target set-size, speed, and familiarity. A mathematical version of MOMIT fitted nicely to the observed data with plausible parameter estimates for the binding capacity and refresh time.     

Multiple social identities and reactivity to daily stress among ethnically diverse young adults

In a sample of 181 young adults from Filipino, European, Latin and Asian American backgrounds, cluster analytic techniques were employed to determine how ethnic, American, family, and religious identity interact to form unique identity configurations. Four clusters emerged: Many Social Identities (MSI), Blended/Low Religious (B/LR), Blended/Low Ethnic and American (B/LEA), and Few Social Identities (FSI). Based on daily diary reports over 14 days, differential reactivity to daily stressors was examined on feelings of anxiety and positive mood. Results suggested that individuals in the MSI, B/LR and B/LEA clusters reported increased anxiety on days when they experienced more stressors. In addition, individuals in the MSI and B/LR clusters reported feeling less positive when they experienced stressors. Multiple identity configurations and their implications for stress reactivity are discussed.     

多目标追踪的任务难度对不同类型非目标选择性抑制的影响

采用多目标追踪（MOT）与点探测刺激觉察任务相结合的实验范式,分别通过改变运动与静止非目标数量,考察追踪难度变化对不同类型非目标选择性抑制的影响。实验一通过改变运动非目标数量为4、5、6,发现当运动非目标数量为6时,追踪难度显著增加,静止非目标上的抑制量也显著增加,而运动非目标上的抑制量则不随追踪难度的变化而变化;实验二改变静止非目标数量为4、5、6,同样发现当静止非目标数量为6时,追踪难度显著增加,静止非目标上的抑制量也显著增加,而运动非目标上的抑制量仍不随追踪难度的变化而变化,且当静止非目标数量为6时,静止非目标上的抑制量显著大于运动非目标,出现了反转现象,其原因可能是视野范围内总的对象数量超出了视觉索引容量,被试改变了对静止与运动非目标的抑制策略。综合实验结果表明,静止非目标上的抑制程度随追踪难度的提高而增加;而运动非目标上的抑制程度对追踪难度的变化不敏感,在不同难度水平上保持相对稳定。     

Krankheitsbewältigung bei multipler Sklerose

Zusammenfassung Obwohl ein erheblicher psychosozialer Versorgungsbedarf bei Patienten mit multipler Sklerose (MS) unstrittig ist, stehen die theoretische Aufarbeitung belastender Aspekte des Krankheitsverlaufs wie die Entwicklung standardisierter Interventionsmaßnahmen nach wie vor am Beginn. In vorliegendem Beitrag werden Konzepte und Modelle der Krankheitsbewältigung als geeigneter theoretischer Bezugsrahmen charakterisiert. Im Anschluss an eine knappe Bestandsaufnahme von Versorgungsbedarf und vorhandenen Versorgungsansätzen werden zunächst kurz Modelle der Krankheitsbewältigung (Coping) vorgestellt, die zur Abbildung spezifischer belastender Folgen der MS geeignet erscheinen. Weiterhin werden in einer Befundübersicht neuere Ergebnisse bewältigungsorientierter Forschung dargestellt, die auch erste Berichte zur Evaluation von Bewältigungstrainings einschließen. Ferner werden Ziele und Techniken, die als Bausteine eines umfassenden Trainings zur Bewältigung von Folgen der MS unverzichtbar erscheinen, erörtert. Abschließend werden offene Forschungsfragen, die die Gestaltung von Bewältigungstrainings betreffen, diskutiert.     

Upper limb movement analysis during gait in multiple sclerosis patients

PurposeGait disorders in multiple sclerosis (MS) are well studied; however, no previous study has described upper limb movements during gait. However, upper limb movements have an important role during locomotion and can be altered in MS patients due to direct MS lesions or mechanisms of compensation. The aim of this study was to describe the arm movements during gait in a population of MS patients with low disability compared with a healthy control group.MethodsIn this observational study we analyzed the arm movements during gait in 52 outpatients (mean age: 39.7 ± 9.6 years, female: 40%) with relapsing-remitting MS with low disability (mean EDSS: 2 ± 1) and 25 healthy age-matched controls using a 3-dimension gait analysis.ResultsMS patients walked slower, with increased mean elbow flexion and decreased amplitude of elbow flexion (ROM) compared to the control group, whereas shoulder and hand movements were similar to controls. These differences were not explained by age or disability.ConclusionUpper limb alterations in movement during gait in MS patients with low disability can be characterized by an increase in mean elbow flexion and a decrease in amplitude (ROM) for elbow flexion/extension. This upper limb movement pattern should be considered as a new component of gait disorders in MS and may reflect subtle motor deficits or the use of compensatory mechanisms.     

Ketamine as a primary predictor of out-of-body experiences associated with multiple substance use

Investigation of “out-of-body experiences” (OBEs) has implications for understanding both normal bodily-self integration and its vulnerabilities. Beyond reported associations between OBEs and specific brain regions, however, there have been few investigations of neurochemical systems relevant to OBEs. Ketamine, a drug used recreationally to achieve dissociative experiences, provides a real-world paradigm for investigating neurochemical effects. We investigate the strength of the association of OBEs and ketamine use relative to other common drugs of abuse. Self-report data (N = 192) from an online survey indicate that both lifetime frequency of ketamine use and OBEs during ketamine intoxication were more strongly related to the frequency of OBEs and related phenomena than other drugs. Moreover, the apparent effects of other drugs could largely be explained by associated ketamine use. The present results, consistent with the role of NMDA receptors in OBEs, should encourage future studies of the role of neurochemical systems in OBEs.     

Multiple commitments in the Chinese context: Testing compatibility, cultural, and moderating hypotheses

This paper evaluates the contribution of the multiple constituencies of commitment framework in explaining work attitudes and behaviors in a sample of Chinese manufacturing workers. Findings suggest that the organization, the supervisor, and co-workers were seen by respondents as separate commitment foci. Although the various commitments were moderately positively correlated, they were related differently to the dimensions of organizational citizenship behavior and withdrawal cognitions, in a way which provides support for the “compatibility” hypothesis. There was only limited support for our “cultural” hypothesis. An analysis of interactions between commitments suggested that commitment to supervisor was a stronger positive predictor of protecting company resources and interpersonal harmony when commitment to work group was lower, providing partial support for our moderating hypotheses.     

Relationships between organizational justice, identification with organization and work unit, and group-related outcomes

This research examined the differential antecedents and consequences of organizational identification and work-unit identification. Specifically, we hypothesized that organization-focused procedural justice and distributive justice would be positively related to organizational identification, whereas supervisor-focused interactional justice would be positively related to work-unit identification. A further hypothesis was that organizational identification would relate to organization-focused outcomes (turnover intentions and extra-role behavior toward the organization), and work-unit identification to work-unit-focused outcomes (extra-role behavior toward the work unit). Our results from a sample of 160 employees of a research institution supported these hypotheses. In addition, we found some evidence that organizational identification and work-unit identification differentially mediated the relationships between organization-focused and supervisor-focused justice, and organization-focused and work-unit-focused outcomes. We discuss our findings in terms of their implications for social-identity research on organizational identification, and for research on organizational justice.