自身免疫性胰腺炎的诊治进展

自身免疫性胰腺炎（AIP）是一种特殊类型的慢性胰腺炎,以胰腺肿大及胰管不规则狭窄为特征.AIP分两个亚型：Ⅰ型AIP好发于亚洲老年人,为淋巴浆细胞硬化性胰腺炎;Ⅱ型AIP多见于西方人,为导管中心型胰腺炎.AIP缺乏特异性血清标志物,诊断主要依赖于其特征性改变.依据AIP诊断标准国际共识,AIP的诊断包括影像学、血清学、胰腺外器官受累、组织病理学和诊断性激素治疗5个方面.糖皮质激素是AIP的首选治疗方法,但复发率高,免疫调节剂对维持AIP的持续缓解具有一定作用.AIP总体预后良好,胰管结石和癌变是其潜在的并发症,但发生率极低.     

Weak Consistency for Ensuring Priority Vectors Reliability

Consistency and transitivity are important and leading research topics in the study of decision‐making in terms of pairwise comparison matrices. In this paper, we search for conditions that, in case of inconsistency, guarantee ordinal compatibility between ordinal ranking (actual ranking) derived from a transitive matrix and cardinal rankings provided by the most usual priority vectors proposed in the scientific literature. We provide the notion of weak consistency; it is a condition weaker than consistency and stronger than transitivity and ensures that vectors associated with a matrix, by means of a strictly increasing synthesis functional, provide a preference order, on the related set of decision elements, equal to the actual ranking. This notion extends, to the case in which the decision‐maker can be indifferent between two or more alternatives/criteria, weak consistency introduced in previous papers under constraint of no indifference. Finally, we introduce an order relation on the rows of the matrix, that is, a simple order if and only if weak consistency is satisfied; this simple order allows us to easily determine the actual ranking on the set of decision elements. Copyright © 2015 John Wiley & Sons, Ltd.     

Toward a contemporary quantitative model of punishment

A direct‐suppression, or subtractive, model of punishment has been supported as the qualitatively and quantitatively superior matching law‐based punishment model (Critchfield, Paletz, MacAleese, & Newland, 2003; de Villiers, 1980; Farley, 1980). However, this conclusion was made without testing the model against its predecessors, including the original (Herrnstein, 1961) and generalized (Baum, 1974) matching laws, which have different numbers of parameters. To rectify this issue, we reanalyzed a set of data collected by Critchfield et al. (2003) using information theoretic model selection criteria. We found that the most advanced version of the direct‐suppression model (Critchfield et al., 2003) does not convincingly outperform the generalized matching law, an account that does not include punishment rates in its prediction of behavior allocation. We hypothesize that this failure to outperform the generalized matching law is due to significant theoretical shortcomings in model development. To address these shortcomings, we present a list of requirements that all punishment models should satisfy. The requirements include formal statements of flexibility, efficiency, and adherence to theory. We compare all past punishment models to the items on this list through algebraic arguments and model selection criteria. None of the models presented in the literature thus far meets all of the requirements.     

State‐Trace Analysis: Dissociable Processes in a Connectionist Network?

Some argue the common practice of inferring multiple processes or systems from a dissociation is flawed (Dunn, 2003). One proposed solution is state‐trace analysis (Bamber, 1979), which involves plotting, across two or more conditions of interest, performance measured by either two dependent variables, or two conditions of the same dependent measure. The resulting analysis is considered to provide evidence that either (a) a single process underlies performance (one function is produced) or (b) there is evidence for more than one process (more than one function is produced). This article reports simulations using the simple recurrent network (SRN; Elman, 1990) in which changes to the learning rate produced state‐trace plots with multiple functions. We also report simulations using a single‐layer error‐correcting network that generate plots with a single function. We argue that the presence of different functions on a state‐trace plot does not necessarily support a dual‐system account, at least as typically defined (e.g. two separate autonomous systems competing to control responding); it can also indicate variation in a single parameter within theories generally considered to be single‐system accounts.     

Publication standards in infancy research: Three ways to make Violation-of-Expectation studies more reliable

The Violation-of-Expectation paradigm is a widespread paradigm in infancy research that relies on looking time as an index of surprise. This methodological review aims to increase the reliability of future VoE studies by proposing to standardize reporting practices in this literature. I review 15 VoE studies on false-belief reasoning, which used a variety of experimental parameters. An analysis of the distribution of p-values across experiments suggests an absence of p-hacking. However, there are potential concerns with the accuracy of their measures of infants’ attention, as well as with the lack of a consensus on the parameters that should be used to set up VoE studies. I propose that (i) future VoE studies ought to report not only looking times (as a measure of attention) but also looking-away times (as an equally important measure of distraction); (ii) VoE studies must offer theoretical justification for the parameters they use, and (iii) when parameters are selected through piloting, pilot data must be reported in order to understand how parameters were selected. Future VoE studies ought to maximize the accuracy of their measures of infants’ attention since the reliability of their results and the validity of their conclusions both depend on the accuracy of their measures.     

Revisiting an Analysis of Threats to Internal Validity in Multiple Baseline Designs

In our previous article on threats to internal validity of multiple baseline design variations (Slocum et al., 2022), we argued that nonconcurrent multiple baseline designs (NCMB) are capable of rigorously demonstrating experimental control and should be considered equivalent to concurrent multiple baselines (CMB) in terms of internal validity. We were fortunate to receive five excellent commentaries on our article from experts in single-subject research design—four of whom endorsed the conclusion that NCMBs should be considered strong experimental designs capable of demonstrating experimental control. In the current article, we address the most salient points made in the five commentaries by further elaborating and clarifying the logic described in our original article. We address arguments related to classic threats including maturation, testing and session experience, and coincidental events (history). We rebut the notion that although NCMBs are strong, CMBs provide an increment of additional control and discuss the application of probability-based analysis of the likelihood of threats to internal validity. We conclude by emphasizing our agreement with many of the commentaries that selection of single-case experimental designs should be based on the myriad subtleties of research priorities and contextual factors rather than on a decontextualized hierarchy of designs.     

进化心理学择偶心理机制假设的跨文化检验

通过对404例天津和432例Boston征婚启事的内容分析,结果发现：（1）男性更关注未来异性配偶的相貌、身材信息,而女性更关注对方的资源与承诺信息,但天津男女征婚者在这两方面都表现得更为强烈;（2）男性随年龄增长,会倾向于更大程度地寻找比自己小的女性,而中美女性则较稳定;（3）Boston人的配偶选择年龄空间较天津人广;（4）在个性特质方面,天津人更关注承诺性,Boston人更关注精神性与“享乐性”。结果表明,进化心理学对男女间差异有较大解释力,但对中美之间的文化差异却缺乏足够说服力。     

Fight,Flight, or Remain Silent? Juggling Multiple Accountabilities throughout the Formative Stage of a Neighborhood Revitalization Initiative

This paper describes the experiences of a research team as they navigated uncertain ethical and political terrain throughout the formative stage of a public housing redevelopment project. Specifically, we discuss the challenges related to balancing multiple accountabilities and the tensions among the various roles and responsibilities that emanated from different accountabilities. Due to contractual obligations to our funding source, established relations with community partners, and an ethical imperative to align with those holding the least power, we grappled with embodying multiple and often conflicting roles. Without oversight provided by our university institutional review board or a clear ethical framework for community psychology research and action, our team was left to negotiate the challenges that emerged through critical reflection and financial considerations. Throughout the case example presented in this paper, we highlight our difficulty in ethical decision‐making with respect to the principles of obligation, disclosure, consent, commitment, and professionalism. Community psychologists often straddle the realms of academia, community partnerships, and conscious engagement with little guidance in navigating often conflicting roles and value systems. We present our narrative to highlight the complexity of scholar‐activism in the context of community psychology and the necessity for developing ethical standards and guidelines tailored to meet the unique needs of community psychologists.     

Evidence of a role for multiple memory systems in behavioral extinction

The acquisition of learned behavior involves multiple memory systems, and hippocampal system damage impairs cognitive learning while leaving stimulus-response habit learning intact. In view of evidence that extinction also involves new learning, the present experiments examined whether multiple memory systems theory may be applicable to the neural bases of extinction. Adult Long-Evans rats were trained to run in a straight-alley maze for food reward. Twenty-four hours later, rats matched for runway latencies during acquisition received extinction training. In a response extinction condition conducive to habit learning, rats performed a runway approach response to an empty food cup. In a latent extinction condition conducive to cognitive learning, rats were placed at an empty food cup without performing a runway approach response. Prior to daily extinction training, neural activity of the dorsal hippocampus was reversibly inactivated via infusion of bupivacaine (0.75%, 0.5 microl/side). Control rats receiving saline infusions displayed extinction behavior in both the response and latent training conditions. In contrast, rats receiving bupivacaine extinguished normally in the response condition, but did not display latent extinction. The findings (1) confirm that learning underlying extinction of the same overt behavior can occur with or without explicit performance of the previously acquired response, (2) indicate that extinction learning produced by response and latent training procedures can be neuroanatomically dissociated, and (3) suggest that similarly to initial task acquisition, the hippocampus may critically mediate extinction in situations requiring the use of cognitive learning, such as when performance of a previously acquired response habit is prevented.