Mechanisms of deficit of visuospatial attention shift in children with developmental coordination disorder: A neurophysiological measure of the endogenous Posner paradigm

The purpose of this study was to investigate and compare the mechanisms of brain activity, as revealed by a combination of the visuospatial attention shifting paradigm and event-related potentials (ERP) in children with developmental coordination disorder (DCD) and typically developing children. Twenty-eight DCD children and 26 typically developing children were recorded with regard to their behavioral performance and ERP measures during a variant of the endogenous Posner paradigm, in which they should react to visual targets preceded by spatial cues or presented uncued. Children with DCD showed longer reaction time and a deficit in inhibitory response capacity when compared to typically developing children. The electrophysiological characteristics also showed distinct modulatory effects upon attentional orienting, anticipatory mechanisms, and cognitive-to-motor transfer in children with DCD: longer cue-P3 and target-N1 latency, smaller target-P3 amplitude, an elongated interval between N2 and the motor response (N2-RT), and small areas on contingent negative variation (CNV). The combined analysis of behavioral performance and ERP data suggested that children with DCD had deficits of slower target identification (N1), less ability in interhemispheric (P3) and cognitive-to-motor transfer speed (N2-RT), as well as a less mature anticipatory and executive process (CNV).     

A Model-Based Approach to Understanding Apraxia in Corticobasal Syndrome

Limb apraxia is a neurological disorder of higher cognitive function characterized by an inability to perform purposeful skilled movements and not attributable to an elementary sensorimotor dysfunction or comprehension difficulty. Corticobasal Syndrome (CBS) is an akinetic rigid syndrome with asymmetric onset and progression with at least one basal ganglia feature (rigidity, limb dystonia or myoclonus) and one cortical feature (limb apraxia, alien hand syndrome or cortical sensory loss). Even though limb apraxia is highly prevalent in CBS (70–80%), very few studies have examined the performance of CBS patients on praxis measures in detail. This review aims to (1) briefly summarize the clinical, neuroanatomical and pathological findings in CBS, (2) briefly outline what limb apraxia is and how it is assessed, (3) to comprehensively review the literature on limb apraxia in CBS to date and (4) to briefly summarize the literature on other forms of apraxia, such as limb-kinetic apraxia and buccofacial apraxia. Overall, the goal of the review is to bring a model-based perspective to the findings available in the literature to date on limb apraxia in CBS.     

眼睛运动如何与记忆相关？

很久以来,人们一直在致力于研究人的眼动与心理活动之间的关系,从而揭示其间的奥妙。众多研究表明,睡眠时的快速眼动（RapidEyeMovements,REM）及其周期对记忆的形成与巩固有重要作用。在清醒状态下,人的眼动就是为了获得视觉信息,如果涉及记忆任务,这就是编码阶段的具体行动。另外,问题解决过程也有眼动参与。总体看来,眼动和记忆之间是一种双向的关系,适当的眼动训练或许能够提高记忆成绩。     

Manual dexterity in the gorilla: bimanual and digit role differentiation in a natural task

The manipulative actions of mountain gorillas Gorilla g. beringei were examined in the context of foraging on hard-to-process plant foods in the field, in particular those used in tackling thistle Carduus nyassanus. A repertoire of 72 functionally distinct manipulative actions was recorded. Many of these actions were used in several variants of grip, finger(s) and movement path, both by different individuals and by the same individual at different times. The repertoire appears somewhat greater than that observed in comparable studies of monkeys, but a far more striking difference is found in the use of differentiated actions in concert. Mountain gorillas routinely and frequently deal with problems that involve: (1) bimanual role differentiation, with the two hands taking different roles but synchronized in time and space, and (2) digit role differentiation, with independent control of parts of the same hand used for separate purposes at the same time. The independent control that allows these abilities, so crucial to human manual constructional ability, is apparently general in African great apes. Role differentiation, between and within the hand, is evidently a primitive characteristic in the human arsenal of skills. Accepted after revision: 6 April 2001 Electronic Publication     

Bimanual Lifting: Do Fingertip Forces Work Independently or Interactively?

Bimanual coordination is a commonplace activity, but the consequences of using both hands simultaneously are not well understood. The authors examined fingertip forces across 4 experiments in which participants undertook a range of bimanual tasks. They first measured fingertip forces during simultaneous lifts of 2 identical objects, noting that individuals held the objects with more force bimanually than unimanually. They then varied the mass of the objects held by each hand, noting that when both hands lifted together performance was equivalent to unimanual lifts. The authors next measured one hand's static grip force while the other hand lifted an object. They found a gradual reduction of grip force throughout the trial, but once again no evidence of one hand influencing the other. In the final experiment the authors tested whether tapping with one hand could influence the static grip force of its counterpart. Although the authors found no changes in static grip force as a direct consequence of the other hand's actions, they found clear differences from one task to the other, suggesting an effect of task instruction. Overall, these results suggest that fingertip forces are largely independent between hands in a bimanual lifting context, but are sensitive to different task requirements.     

Processing ambiguous Spanish se in a minimal chain

The recovery of pieces of information that are not linguistically expressed is a constant feature of the process of language comprehension. In the processing literature, such missing information is generally referred to as “gaps”. Usually, one resolves gaps by finding “fillers” in either the sentence or the context. For instance, in Peter seemed to be upset, Peter is really the subject of being upset but appears as surface subject of seems. Sometimes constituents move, leaving gaps behind. Various Romance languages such as Spanish or Italian have a grammatical particle se/si, which, as it is extremely ambiguous, licenses different sorts of gaps. In Spanish, se can encode at least reflexive, impersonal, and passive meanings. In an eye-tracking experiment we contrast reflexive structures containing postverbal subjects with impersonal structures with no subjects (GAP se vendó apresuradamente el corredor/“the runner bandaged himself hurriedly” vs. GAP se vendó apresuradamente al corridor/“(someone) bandaged the runner hurriedly”). In a second manipulation we contrast the presence of an extra argument with se-passives (GAP se vendó el tobillo el corredor/“the runner bandaged his ankle” vs. GAP se vendó el tobillo al corridor/“the runner's ankle was bandaged”). Our comparisons involve contrasting standard transitive structures with nonstandard word order (postverbal subject and a preverbal subject gap) against inherently complex and less habitual structures such as impersonals (with no subject) or se-passives (with subjects in canonical object position). We evaluate the minimal chain principle (de Vincenzi, 1991 De Vincenzi, M. 1991. Syntactic parsing strategies in Italian, Dordrecht, , The Netherlands: Kluwer. [Crossref] , [Google Scholar]), according to which displacement is costly because it entails complex (derivational) “chains” that must be undone before phrasal packaging can commence. We show the minimal chain principle to be essentially correct when contrasting more complex but more frequent structures with less complex but less frequent structures. A noteworthy feature of this research is that the gaps appear before the fillers in the structures that we analyse.     

Association between objects and body parts mediated by function

Recent accounts of conceptual knowledge suggest that the specific gestures/actions that should be performed in order to use an object for its intended function are an integral part of its mental representation. If this is true, then the information regarding which body part needs activating to interact with the object should also be part of such representation. Starting from the assumption that not only artefacts (i.e., tools), but also natural objects (i.e., fruits and vegetables) have a function, the present study investigates the existence of a link between a specific object and the effector involved in its use. The Implicit Association Test (IAT) paradigm was adopted to test for an association between natural objects and mouth, and between artefacts and hand (Experiment 1) or foot (Experiment 2). Results showed selective links between objects and effectors, based on which body part is needed to carry out the object's function.     

Visual illusions affect both movement planning and on-line control: a multiple cue position on bias and goal-directed action

Over the last decade, there has been an interest in the impact of visual illusions on the control of action. Much of this work has been motivated by Milner and Goodale's two visual system model of visual processing. This model is based on a hypothesized dissociation between cognitive judgments and the visual control of action. It holds that action is immune to the visual context that provides the basis for the illusion-induced bias associated with cognitive judgments. Recently, Glover has challenged this position and has suggested that movement planning, but not movement execution is susceptible to visual illusions. Research from our lab is inconsistent with both models of visual-motor processing. With respect to the planning and control model, kinematic evidence shows that the impact of an illusion on manual aiming increases as the limb approaches the target. For the Ebbinghaus illusion, this involved a decrease in the time after peak velocity to accommodate the 'perceived' size of the target. For the Müller-Lyer illusion, the influence of the figure's tails increased from peak velocity to the end of the movement. Although our findings contradict a strong version of the two visual systems hypothesis, we did find dissociations between perception and action in another experiment. In this Müller-Lyer study, perceptual decisions were influenced by misjudgment of extent, while action was influenced by misjudgment of target position. Overall, our findings are consistent with the idea that it is often necessary to use visual context to make adjustments to ongoing movements.     

Kicking coordination captures differences between full-term and premature infants with white matter disorder

This study explores the relation of white matter disorder (WMD) to intralimb coordination patterns in premature infants with very low birth weight (VLBW). We specifically measured the temporal-spatial characteristics of intralimb coordination patterns of the legs. Three groups of infants were compared at one month corrected age (CA): 10 premature infants born VLBW and WMD (PTWMD), 10 premature infants born VLBW without WMD (PT) and 10 full term infants (FT). Using kinematic variables, we discriminate among VLBW infants with WMD from the two comparison groups. Infants born with WMD maintain patterns of tight coupling among leg joints (all flexion or all extension) while PT and FT term infants have begun to decouple leg joints by this age (combinations of flexion with extension). The coupling pattern is captured through joint correlations, discrete relative phase, and phase plane portraits. The PTWMD infants also demonstrate aberrant patterns of coordination evident through both temporal and spatial characteristics of the kicks. This is the first evidence that movement disorder associated with brain lesions can be identified and quantified with kinematic variables as early as one month of age.     

Ecological Factors Impacting Provider Attitudes Towards Human Service Delivery Reform

Although reform efforts are substantially altering the structural operations and guiding ideological framework of the human service delivery system, little empirical work has been done to systematically examine these transformations. This study examines providers' attitudes regarding two reform elements that are being widely implemented: an increased emphasis on inter-agency collaboration and a shift from a medical model service delivery philosophy, that focuses on client deficits, to one that emphasizes consumer strengths. Through survey data collected from 186 providers from 32 human service agencies in one county, the relationship between providers' perceptions of contextual support for human service delivery reform and providers' attitudes towards these initiatives is explored. The findings from this study support the importance of attending to the ecology in which we initiate system reform efforts. For both reform elements, working within contexts that are perceived as providing ideological and functional support for change was associated with positive provider attitudes towards those changes. Staffs' perceptions of the external environment played the most critical role in shaping staff attitudes. Interestingly, unique aspects of providers' work environments were related to positive attitudes towards the two different reforms. The implications of these findings for the success of human service delivery reform are discussed.