认知损伤的评估

该文介绍了作为认知损伤临床评估最优方法的必要条件。评估的一个重要目的是将关于功能区域的优势和劣势的假设公式化,并据此设定适当的康复目标,评价康复的结果。为了达到这一目的,评估应该开始于康复之前,贯穿于康复过程,并持续到康复结束以后。文中比较了两种评估方法：量表法和假设检验法。为了考察认知损伤及其引起的障碍的变化,测验应该具有信度、敏感性和效度。量表法通常不具备这三个必要条件,而假设检验法在这方面更好。该文以一例获得性失语症的词语产出损伤评估为例,介绍了假设检验法的应用     

Learning from the existence of models: On psychic machines,tortoises, and computer simulations

Using four examples of models and computer simulations from the history of psychology, I discuss some of the methodological aspects involved in their construction and use, and I illustrate how the existence of a model can demonstrate the viability of a hypothesis that had previously been deemed impossible on a priori grounds. This shows a new way in which scientists can learn from models that extends the analysis of Morgan (1999), who has identified the construction and manipulation of models as those phases in which learning from models takes place.     

Imitation of body postures and hand movements in children with specific language impairment

Within the domain-general theory of language impairment, this study examined body posture and hand movement imitation in children with specific language impairment (SLI) and in their age-matched peers. Participants included 40 children with SLI (5 years 3 months to 6 years 10 months of age) and 40 children with typical language development (5 years 3 months to 6 years 7 months of age). Five tests were used to examine imitation and its underlying cognitive and motor skills such as kinesthesia, working memory, and gross motor coordination. It was hypothesized that children with SLI show a weakness in imitation of body postures and that this deficit is not equally influenced by the underlying cognitive and motor skills. There was a group effect in each cognitive and motor task, but only gross motor coordination proved to be a strong predictor of imitation in children with SLI. In contrast, hand movement imitation was strongly predicted by performance in the Kinesthesia task in typically developing children. Thus, the findings show not only that children with SLI performed more poorly on the imitation tasks than their typically developing peers but also that the groups’ performances showed qualitative differences. The results of the current study provide additional support to the view that the weaknesses in children with SLI are not limited to the verbal domain.     

Articulatory mediation of speech perception: A causal analysis of multi-modal imaging data

The inherent confound between the organization of articulation and the acoustic-phonetic structure of the speech signal makes it exceptionally difficult to evaluate the competing claims of motor and acoustic-phonetic accounts of how listeners recognize coarticulated speech. Here we use Granger causation analyzes of high spatiotemporal resolution neural activation data derived from the integration of magnetic resonance imaging, magnetoencephalography and electroencephalography, to examine the role of lexical and articulatory mediation in listeners’ ability to use phonetic context to compensate for place assimilation. Listeners heard two-word phrases such as pen pad and then saw two pictures, from which they had to select the one that depicted the phrase. Assimilation, lexical competitor environment and the phonological validity of assimilation context were all manipulated. Behavioral data showed an effect of context on the interpretation of assimilated segments. Analysis of 40 Hz gamma phase locking patterns identified a large distributed neural network including 16 distinct regions of interest (ROIs) spanning portions of both hemispheres in the first 200 ms of post-assimilation context. Granger analyzes of individual conditions showed differing patterns of causal interaction between ROIs during this interval, with hypothesized lexical and articulatory structures and pathways driving phonetic activation in the posterior superior temporal gyrus in assimilation conditions, but not in phonetically unambiguous conditions. These results lend strong support for the motor theory of speech perception, and clarify the role of lexical mediation in the phonetic processing of assimilated speech.     

Layer and regional effects of environmental enrichment on the pyramidal neuron morphology of the rat

The environmental enrichment (EE) paradigm is widely used to study experience-dependent brain plasticity. Several studies have investigated functional and anatomical EE effects. However, as EE effects are different according to cerebral region, cortical layer, dendritic field and morphological index considered, a univocal characterization of neuronal morphological changes following rearing in enriched environments is lacking.Aim of the present study was to characterize in the rat the effects of EE on the neuronal morphology of frontal and parietal cortical regions, the main target areas of the stimulation provided by the paradigm. Male Wistar rats were housed in an enriched environment for 3.5 months from the 21st postnatal day. For the morphological analysis, biotinylated dextran amine (BDA)-labeled pyramidal neurons were selected from frontal (M1–M2) and parietal (S1–S2) cortical layers III and V. Apical and basal dendritic branching and spines were analyzed using the Sholl method.Results showed that EE increased branching and spines in both layers of frontal cortex, but had a greater effect on apical arborization. In parietal cortex, EE significantly affected branching and spines in layer III but not layer V neurons, in which only a tendency to be influenced by the rearing conditions was observed in basal arborization.It is hypothesized that these multifaceted morphological EE effects are connected to the heavy involvement of a sensory-motor circuit engaged in the guidance of voluntary action and in motor learning activated by EE stimulation.     

The personality assessment system: A radical hypothesis

Two stories are presented. The first story is about a clinical practitioner developing an assessment method beginning with a connection of test “signs” with behavior, and proceeding to a system that could mystify observers. The second story is about the application of scientific methods to explain how the system could work. Together the stories are an example of practice informing science, and science informing practice. The basic hypothesis used is that much of what we call personality is “caused” by differential aptitudes as modified by long-term learning. It is also assumed that people would prefer to use those aptitudes they feel are their better ones and avoid those in which they feel weaker.     

Doing Ethics or Changing for the Better?

In this paper, classical pragmatism is used as a method, not as a substantial ethical theory, to develop “moral pragmatics.” Moral pragmatics offers a constructive approach for making progress where traditional ethical theories converge, and it innovates ethical deliberation. Assuming widespread agreement that real moral problems need practical solutions, the paper addresses two related problems: the missing link between ethical theories and moral practice, and the question of who is in charge of finding such solutions. It argues that “conscience” can create a link between ethical knowledge and moral practice, and that this partly discharges “the ethicist” from the task of solving problems that are not really, or not only, hers. Two specific methodological innovations are suggested that go beyond admonitions to render ethics sensitive to context. Instead, a reevaluation of “casuistry” and a sensitivity for “finding the right words” give an idea of how to achieve this goal.     

Sensory features of mental images in the framework of human actions

What determines the sensory impression of a self-generated motor image? Motor imagery is a process in which subjects imagine executing a body movement with a strong kinesthetic and/or visual component from a first-person perspective. Both sensory modalities can be combined flexibly to form a motor image. 90 participants of varying ages had to freely generate motor images from a large set of movements. They were asked to rate their kinesthetic as well as their visual impression, the perceived vividness, and their personal experience with the imagined movement. Data were subjected to correlational analyses, linear regressions, and representation similarity analyses. Results showed that both action characteristics and experience drove the sensory impression of motor images with a strong individual component. We conclude that imagining actions that impose varying demands can be considered as reexperiencing actions by using one’s own sensorimotor representations that represent not only individual experience but also action demands.     

Perception and action in a far-aiming task: Inhibition demands and the functionality of the Quiet Eye in motor performance

It is incontestable that high motor performance requires an optimal coupling between perception and action. In sports as well as in professional tasks, the Quiet Eye (QE) – defined as the final fixation before movement initiation – has been found to explain a considerable amount of variance in motor performance and expertise. In the current series of studies, the underlying mechanisms of this perception-action variable were further investigated by testing predictions of the inhibition hypothesis. According to the inhibition hypothesis, the functionality of the QE is to shield movement parametrization. By manipulating the demands during response selection (Experiment 1 and Experiment 2) and movement control (Experiment 2) in a far-aiming task, it was found that – in line with the predictions – QE duration increased with increasing inhibition demands. This effect was mainly driven by the similarity rather than the number of possible actions. Moreover, the relation between inhibition demands and QE-duration were sustained through both response selection and movement control, which is perfectly in line with the notion of a continuous perception-action cycle in motor behavior. In sum, these findings corroborate the inhibition function as an integral component within a cognitive understanding of the QE phenomenon.