小学儿童情绪认知发展研究

本研究采用故事情境法探究小学儿童情绪认知的发展。随机抽取60名小学儿童（2、4、6年级各20名）,研究他们对五种不同的情绪状态识别、情绪原因认知、情绪外在行为表现认知以及对情绪后继调节方式的认知发展特点。结果发现：总体而言,情绪认知在小学不同年级有明显发展;基本情绪认知最好,其次是积极自我意识情绪认知和冲突情绪认知,对消极自我意识情绪的认知最差;情绪识别和情绪原因认知明显好于情绪行为认知和情绪调节认知;对情绪表现者的情绪认知明显好于对情绪接受者的情绪认知。     

Visual processing of multielement arrays and selective backward masking

In the first of two selective masking experiments, 7-letter rows were followed at several ISIs by a mask or no-mask and a bar-marker partial report cue. The results suggest that the arrays were processed ends-first and then, in general, from both ends towards the middle. In the second experiment, bar-marker partial report cues were presented at the onset or offset of 6-letter/1-digit or 7-letter rows. The subjects could not anticipate the category of the to-be-reported item with the alphanumeric displays. With a delayed cue, selective masking was obtained with both mixed category and pure letter arrays, but with simultaneous cuing, masking was always distributed across all serial positions. The results suggest that the subjects: (a) abstracted some information about category from the mixed arrays during an initial parallel stage of processing, (b) selectively attended to mainly the cued item with simultaneous probes with homeogeneous and mixed category displays, and (c) employed an ends-first processing strategy with both types of arrays when the bar-marker partial report cue was delayed.     

Relationship between response to graded exposure and marital satisfaction in agoraphobics

Agoraphobics who were satisfied in their marriage responded well to graded exposure and maintained their improvement to 3-months follow-up. Satisfaction with self and partner remained unchanged in patient and spouse. Agoraphobics who were dissatisfied with their marriage improved initially with graded exposure but later lost most of their gains and reported no change in general neurotic symptoms. Marital dissatisfaction also remained unchanged. Patients' dissatisfaction with their spouses, measured before therapy, predicted outcome in the sample as a whole.     

ACHIEVING AND MAINTAINING COMPLIANCE WITH THE KETOGENIC DIET

The ketogenic diet, a treatment for intractable epilepsy, is rarely initiated because it requires strict compliance with a diet that is perceived to be unpalatable. In a case study of a 15-year-old girl with uncontrolled epilepsy, we used a stimulus-choice procedure to assess relative preferences of 33 foods from the diet and to develop two treatments based on Premack's principle. The results of a multielement analysis showed that both treatments increased dietary compliance. Compliance was maintained with generalization of treatment across settings, and was associated with a 40% reduction in seizures.     

Evidence for scanning with unilateral visual presentation of letters

When letters and words are presented tachistoscopically, material from the right visual field (RVF) can be reported more accurately than that from the left visual field (LVF). The RVF superiority may reflect either left hemispheric dominance for language or directional scanning. Previous studies have deliberately focused on the cerebral asymmetry factor while "controlling" scanning and, thus, have cast some doubt on the potency of the scanning factor. Two experiments were conducted to show that scanning can induce a RVF superiority comparable to that often associated with cerebral asymmetry. The first experiment required bilingual subjects to report six English or six Hebrew letters, shown briefly in either the LVF or RVF, with order of report controlled. A RVF superiority found with English characters was matched by an equal but opposite LVF effect with Hebrew. In a second experiment, five English characters were shown briefly in either the LVF or RVF, and subjects had to identify a single character indicated by a post exposural cue. Using a spatial cue to by pass scanning, there were no field differences; with an ordinal position cue--a procedure thought to force scanning--there was a strong RVF superiority. The results show clearly that scanning can induce visual field differences.     

THE EFFECTIVENESS OF REINFORCEMENT,RESPONSE COST,AND MIXED PROGRAMS ON CLASSROOM BEHAVIORS1

Six elementary school children served as subjects in an experiment comparing the relative effectiveness of (1) token reinforcement, in which children received tokens for attending and for correct arithmetic performance; (2) response cost, in which children received “free” tokens at the start of a period but lost them for inattention and for arithmetic performance below a specified level; and (3) a combination of both token reinforcement and response cost. During training, the six subjects received all three procedures in counterbalanced sequence. The effects of the three procedures were assessed by a within-subject comparison divided into three phases: (i) baseline, (ii) training, (iii) withdrawal of tokens. Introduction of the three token procedures markedly increased the two dependent measures. However, there were no differences across the procedures in the amount of change produced in either attending behavior or arithmetic performance. During baseline, the subjects averaged 29% attending behavior and 6.4 correct problems. These levels increased to 85% for attending behavior and 11.4 correct problems for arithmetic performance during training. Removal of all token procedures significantly decreased attending behavior (to an average of 65%), but produced a nonsignificant reduction in arithmetic performance (to an average of 7.6 correct problems). There was evidence that this lack of differential effects of the three token procedures was not due to an inability to discriminate among them. Furthermore, the subjects were evenly divided in their preference for the three procedures.     

阿尔茨海默病生物学标志物研究进展

阿尔茨海默病（AD）是常见的中枢神经系统变性疾病,是痴呆最常见的病因,发病率高.病理特征为老年斑及神经元纤维缠结.AD的确诊有赖病理学,临床诊断极其耗时.由于尚无准确的早期诊断方法,常使AD患者错过早期治疗的时机,这成为制约有效防控AD的瓶颈问题.因此寻找高敏感性、特异性、无创性的生物学标志物对AD的早期诊断至关重要.本文仅将目前较为广泛研究的生物学标志物及其研究现状作一概述.分别对脑脊液、血液、尿液及唾液中的AD标志物作逐一介绍.     

In conversation with J. Philippe Rushton

The interview covers Rushton’s background in England, South Africa, and Canada, his education at the University of London (B.Sc., 1970; Ph.D., 1973), and his early research (1970–1980) on the social learning of generosity in 7- to 11-year olds. In his first book, Altruism, socialization, and society (1980), Rushton solved two “anomalies” for his social learning perspective—altruism in animals and traits in people—causing a “paradigm shift” for him toward sociobiology. He spent January to June 1981 at the University of California, Berkeley, to study the longitudinal stability of personality traits like altruism. There, he was influenced by Jensen’s work on g and race differences in rate of maturation and two-egg twinning. Subsequently, Rushton found that across 60 variables, Europeans fall between East Asians and Africans, closer to East Asians. He extrapolated Wilson’s (fast–slow) r-K life history theory to explain the pattern. Also covered is Rushton’s research on the heritability of altruism, and Genetic Similarity Theory explaining assortative mating and ethnic nepotism. Spouses and best friends are as similar as half-siblings and people randomly chosen from the same ethnic group are as related as first cousins. Altruism follows lines of similarity to replicate genes effectively. Rushton’s research on creativity is described.     

炎症性肠病的药物治疗现状及进展

炎症性肠病（IBD）病程迁延反复,影响患者生活质量,耗费卫生资源。虽然传统药物如5-氨基水杨酸、糖皮质激素、免疫抑制剂等仍是目前治疗主流,但是大量有关发病机制的研究以及循证医学的发展对IBD的治疗产生了积极的推进作用。IBD的治疗正步入免疫调节的生物学时代,多种新型生物制剂的出现为IBD的治疗提供了新的策略和选择。现就目前IBD药物治疗现状以及最新进展进行综述,以期对临床IBD治疗提供参考。