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171.
    
This study provides an innovative, compassionate and culturally informed method for psychotherapy research, using object elicitation with 13 participants from vulnerable groups. It examines the positive impact it has on building the research alliance, enhanced depth of sharing within qualitative research interviews and emic ways of knowing through the engagement with a culturally relevant, tangible, internalised or transitional object brought by vulnerable participants from diverse cultural contexts of origin. Results showcase how a creative and compassionate research method can promote a culturally informed research alliance with vulnerable participants, helping to build trust, rapport and relational depth; encourage elicitation of experiences; and empower emic and subjugated voices. The implications of this study make the case for the inclusion of object elicitation as a creative and compassionate method in qualitative research with traumatised and vulnerable individuals, which should be used as part of a culturally informed approach to psychotherapy research.  相似文献   
172.
To elucidate processes underlying therapeutic change in a large-scale randomized clinical trial, we examined whether alterations in self-reported parenting practices were associated with the effects of behavioral, medication, or combination treatments on teacher-reported outcomes (disruptive behavior, social skills, internalizing symptoms) in children with attention-deficit hyperactivity disorder (ADHD). Participants were 579 children with Combined-type ADHD, aged 7–9.9 years, in the Multimodal Treatment Study of Children with ADHD (MTA). We uncovered 2 second-order factors of parenting practices, entitled Positive Involvement and Negative/Ineffective Discipline. Although Positive Involvement was not associated with amelioration of the school-based outcome measures, reductions in Negative/Ineffective Discipline mediated improvement in children's social skills at school. For families showing the greatest reductions in Negative/Ineffective Discipline, effects of combined medication plus behavioral treatment were pronounced in relation to regular community care. Furthermore, only in combination treatment (and not in behavioral treatment alone) was decreased Negative/Ineffective Discipline associated with reduction in children's disruptive behavior at school. Here, children in families receiving combination treatment who showed the greatest reductions in Negative/Ineffective Discipline had teacher-reported disruptive behavior that was essentially normalized. Overall, the success of combination treatment for important school-related outcomes appears related to reductions in negative and ineffective parenting practices at home; we discuss problems in interpreting the temporal sequencing of such process-outcome linkages and the means by which multimodal treatment may be mediated by psychosocial processes related to parenting.  相似文献   
173.
创新和知识经济与促肝细胞生长素的研制   总被引:2,自引:0,他引:2  
创新是一个民族进步的灵魂,是科研工作的核心,是知识经济对知识的根本要求。促肝细胞生长素是治疗肝炎的有效药物,该药物研制成功的关键在于创新。纵观其研制过程的创新思路与实践,将有助于我们更新科研观念,增加创新意识。  相似文献   
174.
In this paper, the constrained maximum likelihood estimation of a two-level covariance structure model with unbalanced designs is considered. The two-level model is reformulated as a single-level model by treating the group level latent random vectors as hypothetical missing-data. Then, the popular EM algorithm is extended to obtain the constrained maximum likelihood estimates. For general nonlinear constraints, the multiplier method is used at theM-step to find the constrained minimum of the conditional expectation. An accelerated EM gradient procedure is derived to handle linear constraints. The empirical performance of the proposed EM type algorithms is illustrated by some artifical and real examples.This research was supported by a Hong Kong UCG Earmarked Grant, CUHK 4026/97H. We are greatly indebted to D.E. Morisky and J.A. Stein for the use of their AIDS data in our example. We also thank the Editor, two anonymous reviewers, W.Y. Poon and H.T. Zhu for constructive suggestions and comments in improving the paper. The assistance of Michael K.H. Leung and Esther L.S. Tam is gratefully acknowledged.  相似文献   
175.
176.
Enhancing exposure-based therapy from a translational research perspective   总被引:1,自引:0,他引:1  
Combining an effective psychological treatment with conventional anxiolytic medication is typically not more effective than unimodal therapy for treating anxiety disorders. However, recent advances in the neuroscience of fear reduction have led to novel approaches for combining psychological therapy and pharmacological agents. Exposure-based treatments in humans partly rely on extinction to reduce the fear response in anxiety disorders. Animal studies have shown that D-cycloserine (DCS), a partial agonist at the glycine recognition site of the glutamatergic N-methyl-D-aspartate receptor facilitates extinction learning. Similarly, recent human trials have shown that DCS enhances fear reduction during exposure therapy of some anxiety disorders. This article discusses the biological and psychological mechanisms of extinction learning and the therapeutic value of DCS as an augmentation strategy for exposure therapy. Areas of future research will be identified.  相似文献   
177.
Introduction     
This issue of Clinical Child and Family Psychology Review, Children Exposed to Domestic Violence: Current Status and Research Directions, addresses the current status of our knowledge as well as critical research needs in the area of children exposed to domestic violence. Although much has been learned in recent years about children exposed to violence, significant research gaps remain, the identification of which may help to build a more complete and rigorous science base in this area. This journal issue represents the distillation of a 3-day workshop on children exposed to violence, held in July of 2002, that identified what is known about children exposed to violence and what this information tells us about future research directions. Although many federal agencies have supported some research in this area, there is a need for more targeted attention on the topic, particularly with regard to measurement, sampling, and interventions/services. The papers in this issue were selected with these themes in mind. Although no single issue could cover the entire field, we intend to offer a representative sample of where we are and where we need to go with the hope of stimulating additional thought, collaboration, and research in this important area.  相似文献   
178.
Psychoanalysis has been slow to acknowledge attachment theory as one of its own. Yet traditions of observational and representational research associated with it have much to offer in shedding light on intrapsychic as well as interpersonal phenomena. This paper explores these traditions and their potential clinical utility for couple psychoanalytic psychotherapy. In particular, attention is drawn to behaviour and representations associated with the experience of reunion in therapy sessions.  相似文献   
179.
In recent decades, cognitive and behavioral scientists have learned a great deal about how people think and behave. On the most general level, there is a basic consensus that many judgments, including ethical judgments, are made by intuitive, even unconscious, impulses. This basic insight has opened the door to a wide variety of more particular studies that investigate how judgments are influenced by group identity, self‐conception, emotions, perceptions of risk, and many other factors. When these forms of research engage ethical issues, they are sometimes called empirical ethics. This essay argues that the field of religious ethics would benefit from a more robust engagement with empirical ethics than it has thus far undertaken. In doing so, it offers a brief account of how issues of moral psychology and moral anthropology have been treated in religious ethics, and it highlights ways that the scientific findings challenge some prevailing norms in religious ethics. It ends by suggesting avenues by which religious ethics research could productively engage empirical ethics.  相似文献   
180.
新世纪预防医学发展方向的浅议   总被引:3,自引:0,他引:3  
现代预防医学所面临的主要研究内容从传统的传染性疾病向以社会、环境等因素所导致的疾病转移,不仅需要研究人类的生物属性,而且在人类的社会属性以及和种因素对人群健康的影响、消除和控制这些方面有更为广泛的研究任务,并且需要从预防的理论、技术加以拓展。  相似文献   
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