负责任创新中医疗人工智能应用技术的伦理审视

负责任创新是目前探讨人工智能技术在医疗领域应用的重要理论,也是引导医疗人工智能应用技术向善发展的理想图景,其基本结构主要包括预测、反思、协商、反应四个维度。当前,医疗人工智能应用技术受技术“黑箱特质”的影响,暴露了其在安全、隐私、道德、分配等方面的伦理风险,桎梏了其应用于医疗事业的广阔前景。面对医疗人工智能应用技术的伦理困境,从其技术研发、设计、应用、跟踪等全过程分析嵌入负责任创新四维度模型,能够有效缓解医疗人工智能应用技术在实践中存在的伦理风险,从而真正实现其为人类健康的精准赋能。

     

人体生物医学研究中受试者权益保护对策

在人体生物医学研究日益发达的今天,受试者权益保护问题逐渐浮出水面。目前我国对受试者的保护主要依赖于知情同意书和伦理委员会,关于受试者权益保护的规范性文件存在层级低、不系统和不完整等问题。建立专门的受试者保护法,完善受试者权益保护相关制度迫在眉睫。研究认为,制定专门的人体生物医学研究受试者权益保护法律,完善伦理委员会制度,推行强制保险以及救济金制度,建立严格的责任体系、开展积极的社会教育是受试者权益保护的基本对策。     

循证医学的认识论探究

循证医学的兴起被认为是医学界重要的现代化运动,其哲学基础却一直倍受质疑。回顾了循证医学概念的发展和基本假设,整理了从认识论视角质疑循证医学的若干观点,着重介绍循证医学倡导者对循证医学认识论的基本看法,包括证据和知识的关系,观察到的、可观察的和不可观察的事实间的关系,正确地进行观察,指出循证医学不是全新的医学证据产生与运用理论,而是对多种科学推理规则的综合运用。循证医学是应客观需要而产生,因争议而不断自我完善,实现其迅速发展。     

Looking Forward: The Potential of Creativity for Social Justice and Equity (and Other Exciting Outcomes)

This brief essay argues for the importance for more work on how creativity predicts positive outcomes, with a particular emphasis on expanding our definitions of these positive outcomes. The way that creativity may lead to increased equity and social justice is used as an example of these type of potential research questions.     

In Pursuit of Everyday Creativity

Creativity researchers have long paid careful attention to individual creativity, beginning with studies of well‐known geniuses, and expanding to personality, biographical, cognitive, and social‐psychological studies of individual creative behavior. Little is known, however, about the everyday psychological experience and associated creative behavior in the life and work of ordinary individuals. Yet evidence is mounting that such individuals can be responsible for important instances of creativity and innovation in the world: open innovation, user innovation, and citizen innovation. Research into this phenomenon could do much to advance the study and practice of creativity.     

纵向数据分析方法

纵向研究方法是心理学研究领域的一种重要方法。近年来,国外在纵向研究数据分析方法上取得了一系列理论和应用上的进展。章对此方法进行了简要的回顾,并重点阐述了最近发展起来的纵向研究的方法：多层线性模型和潜变量增长曲线模型,并在此基础上对几种常用的方法进行了比较。     

个人化设计在临床研究中的应用——从个体角度研究个体差异

本文从有关研究证据的基础上,介绍了个人化设计的理论基础和实验设计,并在此基础上讨论了个人化设计在临床研究领域中的应用价值,总结出一种适合临床病人使用的研究程序。个人化设计允许对个体的个人价值进行分析,并能同时研究不同刺激信息的作用,在个体水平上分析个体差异。通过简化了的实验程序,个人化设计为解决临床研究中的问题提供了一种新的思维方式。文中还对相关研究法的局限进行了讨论。     

基于自我决定理论的工作动机研究脉络及未来走向

对2018年5月为止基于自我决定理论的工作动机研究英文文献的系统检索得到了97篇实证研究样本。基于自我决定理论的核心假设, 运用“环境-基本心理需要-工作动机-结果”的理论模型对工作动机前因和结果的研究脉络进行了仔细地分析和归纳, 结果表明员工基本心理需要满足和自主性工作动机作为中介变量可解释自主性支持的工作环境和员工个体特征对工作行为、态度和心理健康的积极影响。将来的主要研究议题：一是对控制性工作环境具体因素对员工基本心理需要阻滞、控制性动机和去动机以及员工工作行为、态度和心理健康影响的研究; 二是不同动机类型对员工业绩、行为和态度影响的过程以及情境因素的研究; 三是外部奖励(包括薪酬、基于业绩的奖励等)对员工工作动机、基本心理需要、工作业绩和心理健康的影响及边界条件的深入研究。     

Private-Sector Research Ethics: Marketing or Good Conflicts Management? The 2005 John J. Conley Lecture on Medical Ethics

Pharmaceutical companies are major sponsors of biomedical research. Most scholars and policymakers focus their attention on government and academic oversight activities, however. In this article, I consider the role of pharmaceutical companies’ internal ethics statements in guiding decisions about corporate research and development (R&D). I review materials from drug company websites and contributions from the business and medical ethics literature that address ethical responsibilities of businesses in general and pharmaceutical companies in particular. I discuss positive and negative uses of pharmaceutical companies’ ethics materials and describe shortcomings in the companies’ existing ethics programs. To guide employees and reassure outsiders, companies must add rigor, independence, and transparency to their R&D ethics programs.     

EFFECTS OF TREATMENT INTEGRITY FAILURES DURING DIFFERENTIAL REINFORCEMENT OF ALTERNATIVE BEHAVIOR: A TRANSLATIONAL MODEL

Differential reinforcement of alternative behavior (DRA) is used frequently as a treatment for problem behavior. Previous studies on treatment integrity failures during DRA suggest that the intervention is robust, but research has not yet investigated the effects of different types of integrity failures. We examined the effects of two types of integrity failures on DRA, starting with a human operant procedure and extending the results to children with disabilities in a school setting. Human operant results (Experiment 1) showed that conditions involving reinforcement for problem behavior were more detrimental than failing to reinforce appropriate behavior alone, and that condition order affected the results. Experiments 2 and 3 replicated the effects of combined errors and sequence effects during actual treatment implementation.