临床外伤性视神经病变过度医疗的探讨

外伤性视神经病变是一类严重损害视功能的疾病,临床治疗上普遍存在着过度治疗的问题。原因是多样的,治疗标准不统一是主要原因。依据循证医学的成果,对临床外伤性视神经病变现阶段存在的过度医疗进行分析探讨,并提出了医者针对外伤性视神经病变过度医疗应采取的措施,获得最优化的诊疗方案。     

The effects on classifier performance of 2D discrete wavelet transform analysis and whale optimization algorithm for recognition of power quality disturbances

Power Quality (PQ) is becoming more and more important day by day in the electric network. Signal processing, pattern recognition and machine learning are increasingly being studied for the automatic recognition of any disturbances that may occur during the generation, transmission, and distribution of electricity. There are three main steps to identify the PQ disturbances. These include the use of signal processing methods to calculate the features representing the disturbances, the selection of those that are more useful than these feature sets to prevent the creation of a complex classification model, the creating a classification model that recognizes multiple classes using the selected feature subsets. In this study, one-dimensional (1D) PQ disturbances signals are transformed into two-dimensional (2D) signals, 2D discrete wavelet transforms (2D-DWT) are used to extract the features. The features are extracted by using the wavelet families such as Daubechies, Biorthogonal, Symlets, Coiflets and Fejer-Korovkin in 2D-DWT to analyze PQ disturbances. Whale Optimization Algorithm (WOA) and k-nearest neighbor (KNN) classifier determine the feature subsets. Then, WOA and k nearest neighbor (KNN) classifier are used to determine the feature group. By using KNN and Support Vector Machines (SVM) classification methods, Classifier models that distinguish PQ disturbances are formed. The main aim of the study is to determine the features derived from 2D wavelet coefficients for different wavelet families and to determine which of them has a better classification performance to distinguish PQ disturbances signals. At the same time, different classification methods are simulated and a model which can classify PQ disturbances signals with high performance is created. Also, the generated models are analysed for their performance in terms of different noise levels (40 dB, 30 dB, 20 dB). The result of this simulation study shows that the model developed to classify PQ disturbances is superior to conventional models and other 2D signal processing methods in the literature. In addition, it was concluded that the proposed method can cope better with noisy signals by low computational complexity and higher classification rate.     

Multiobjective optimization for interwoven systems

In practical situations, complex systems are often composed of subsystems or subproblems with single or multiple objectives. These subsystems focus on different aspects of the overall system, but they often have strong interactions with each other and they are usually not sequentially ordered or obviously decomposable. Thus, the individual solutions of subproblems do not generally induce a solution for the overall system. Here, we strive to identify “re‐composition architectures” of such “interwoven” systems. Our intention is to connect the subsystems adequately, analyze the resulting performance, model/solve the overall system, and improve the overall solution instead of just solving each subsystem separately. We review recent developments in this field and discuss modeling and solution paradigms in a general and unified framework using the example of an interwoven system consisting of two interacting subsystems.     

An interactive multiobjective programming approach to combinatorial data analysis

Combinatorial optimization problems in the social and behavioral sciences are frequently associated with a variety of alternative objective criteria. Multiobjective programming is an operations research methodology that enables the quantitative analyst to investigate tradeoffs among relevant objective criteria. In this paper, we describe an interactive procedure for multiobjective asymmetric unidimensional seriation problems. This procedure uses a dynamic-programming algorithm to partially generate the efficient set of sequences for small to medium-sized problems, and a multioperation heuristic to estimate the efficient set for larger problems. The interactive multiobjective procedure is applied to an empirical data set from the psychometric literature. We conclude with a discussion of other potential areas of application in combinatorial data analysis.Stephanie Stahl is a freelance writer and editor. She can be reached via e-mail at s-stahl@worldnet.att.net.     

Multicriteria Optimization Technique for Optimal Design of Orthotropic Bridges

The design improvement of large‐scale structures such as cable stayed and suspension bridges with large spans is one of the major engineering optimization problems faced by design engineers. In many real‐life engineering design problems, it is necessary to carry out large‐scale experimental physical models for only one prototype to construct the feasible solution set that is too expensive and not practical. For these reasons, an experimental search for optimal solutions is often not carried out at all. This paper presents a technique for multicriteria analysis, which involve the finite element analysis of the prototype in the optimization process. The improvement of the Suez Canal Bridge in Egypt is introduced as a real‐life large‐scale case study. The parameter space investigation method, the visual basic for application programming language, and Femap as finite element analysis software provide an implementation tools to construct the feasible and Pareto solution sets for the studied bridge. An efficient combination between the parameter space investigation method and the finite element programme was successfully investigated to obtain the Pareto solution set. This study shows possibility to apply the multicriteria optimization method for more applications on different large‐scale structural systems in the future. Copyright © 2013 John Wiley & Sons, Ltd.     

Multiobjective Optimization for the Asset Allocation of European Nonlife Insurance Companies

An optimal asset allocation is crucial for nonlife insurance companies. The most previous studies focused on this topic use a mono‐objective technique optimization. This technique usually allows the maximization of shareholders' expected utility. As nonlife insurance company is a complex system, it has many stakeholders other than shareholders. So, the satisfaction of the shareholders' expected utility cannot lead usually to the satisfaction of other stakeholders' objectives. Therefore, the focus on utility maximization can be a destruction source of other objectives such as productivity, competitiveness and solvency. Our developed model integrates simulation approach with a multiobjective particle swarm optimization algorithm. This model insures an optimal asset allocation that maximizes, simultaneously, shareholders expected utility and technical efficiency of European nonlife insurance companies. The empirical application conducts a comparison between the attained results with multiobjective optimization technique and mono‐objective technique to search the optimal asset allocation for nonlife insurance companies. Our results show that the investment portfolio will be more diversified between most available investment assets. In addition, any decision maker should take account of different stakeholders' objectives. Accordingly, multiobjective optimization allows us to find the best asset allocation that maximizes simultaneously expected utility and technical efficiency of nonlife insurance companies. Copyright © 2013 John Wiley & Sons, Ltd.     

Analytical Inverse Optimization in Two-Hand Prehensile Tasks

The authors explored application of analytical inverse optimization (ANIO) method to the normal finger forces in unimanual and bimanual prehensile tasks with discrete and continuously changing constraints. The subjects held an instrumented handle vertically with one or two hands. The external torque and grip force changed across trials or within a trial continuously. Principal component analysis showed similar percentages of variance accounted for by the first two principal components across tasks and conditions. Compared to unimanual tasks, bimanual tasks showed significantly more frequent inability to find a cost function leading to a stable solution. In cases of stable solutions, similar second-order polynomials were computed as cost functions across tasks and condition. The bimanual tasks, however, showed significantly worse goodness-of-fit index values. The authors show that ANIO can be used in tasks with slowly changing constraints making it an attractive tool to study optimality of performance in special populations. They also show that ANIO can fail in multifinger tasks, likely due to irreproducible behavior across trials, more likely to happen in bimanual tasks compared to unimanual tasks.     

Perceived Occurrence of the Second of Two Closely Spaced Stimuli in a Long Movement

A 75-deg. movement of the arm in the vertical plane was used to examine the conscious perception of the apparent time of occurrence of a reversal signal S₂. A marked perceptual delay was found whether S₂ occurred during or after the reaction time to the first stimulus. This finding was consistent with Henry’s memory drum theory of neuromotor response, as well as with the efference theory of conscious perception proposed by Festinger and associates.     

Molar optimization versus delayed reinforcement as explanations of choice between fixed-ratio and progressive-ratio schedules.

In a discrete-trials procedure, pigeons chose between a fixed-ratio 81 schedule and a progressive-ratio schedule by making a single peck at the key correlated with one or the other of these schedules. The response requirement on the progressive-ratio schedule began at 1 and increased by 10 each time the progressive-ratio schedule was chosen. Each time the fixed-ratio schedule was chosen, the requirement on the progressive-ratio schedule was reset to 1 response. In conditions where there was no intertrial interval, subjects chose the progressive-ratio schedule for an average of about five consecutive trials (during which the response requirement increased to 41), and then chose the fixed-ratio schedule. This ratio was larger than that predicted by an optimality analysis that assumes that subjects respond in a pattern that minimizes the response-reinforcer ratio or one that assumes that subjects respond in a pattern that maximizes the overall rate of reinforcement. In conditions with a 25-s or 50-s intertrial interval, subjects chose the progressive-ratio schedule for an average of about eight consecutive trials before choosing the fixed-ratio schedule. This change in performance with the addition of an intertrial interval was also not predicted by an optimality analysis. On the other hand, the results were consistent with the theory that choice is determined by the delays to the reinforcers delivered on the present trial and on subsequent trials.