Differential effects of beta-adrenergic receptor blockade in basolateral amygdala or insular cortex on incidental and associative taste learning

The importance of central β-adrenergic system has been essentially investigated in aversive/emotional learning tasks. However, recent data suggest that the β-adrenergic system is also required for incidental taste learning. In the present study we evaluated in rats whether β-adrenergic receptor activity is required for taste habituation, an incidental taste learning, and also for conditioned taste aversion (CTA) learning, an associative learning. To address this issue, a low dose of the β-adrenergic antagonist propranolol was infused before learning in either the basolateral amygdala (BLA) or the insular cortex (IC), two forebrain areas reported to play a key role in taste memory formation. Incidental taste learning was assessed using a single presentation of the sweet taste saccharin 0.1%, which is sufficient to increase saccharin consumption (relative to water baseline) during a second presentation. CTA was assessed by pairing the first saccharin 0.1% presentation with a delayed gastric malaise, thus causing a decrease in saccharin consumption (relative to water baseline) during a second presentation. Propranolol infusion in BLA (1 μg/0.2μl) or IC (2.5 μg/0.5 μl) before the first taste exposure impaired incidental taste learning but did not affect CTA. These results highlight the important role played by the β-adrenergic receptor activation in cortical and amygdaloid structures during taste learning. Moreover, they are the first to suggest that incidental learning is more sensitive to blockade of noradrenergic system than associative learning.     

Asymmetrical retention functions for sequences of light flashes or tone bursts in the rat

In Experiment 1, rats were trained in a symbolic delayed matching-to-sample task to discriminate sample stimuli that consisted of sequences of magazine light flashes. The intertrial interval was illuminated by the houselight for Group Light, and it was dark for Group Dark. Retention functions exhibited a choose-many response bias when the delay interval was illuminated by the houselight in both groups, and no consistent response bias when the delay interval was dark. In Experiment 2, rats were trained to discriminate sample stimuli that consisted of sequences of tone bursts. During delay testing, a different tone (i.e., different frequency and location than the sample tone) was present or absent during the delay interval. The retention functions exhibited a significant choose-many bias when tone was present during the delay and a choose-few bias when tone was absent. Asymmetrical retention functions for tone burst and light flash sequences are due to the similarity between the stimulus conditions of the delay interval and the modality of the sequential event being discriminated. These results are consistent with an instructional ambiguity explanation of response biases in memory for number.     

记忆中"曾经"的承诺

该文关注“曾经”与“承诺”—“复仇”与“拯救”如何相关特别是如何转换的“记忆的政治”。问题的背景是苦难:作为存在论或现象着的生活世界的基本事实,它是人类唯一可以普遍面对神、面对政治的“救赎地”,而不是“弥撒”中可以流逝的将来时,或在“复仇”中永远走不出的过去时。这里重要的是记忆形式的时间结构发生了根本的变化。因而“曾经”不是无生命力的过去压力(如尼采所批判的和本雅明所清理的);也不是简单转化为复仇的有生命力的权力意志即强权政治(如尼采所一厢情愿的);而是走出复仇的拯救———即走出过去时的———“记忆”中的“曾经”的“承诺”。但事实上,它已不能由西方文化的特质独立承担了。     

Differences in Fear of Isolation as an explanation of Cultural Differences: Evidence from memory and reasoning

Previous research suggests that members of East Asian cultures show a greater preference for dialectical thinking and sensitivity to context information than do Westerners. We suggest this difference is rooted in a greater chronic Fear of Isolation (FOI) in East Asians than in Westerners. To support this hypothesis, we manipulated FOI in a group of Westerners and assessed their relative preference for dialectical proverbs and sensitivity to context. For cross-cultural validation of our hypothesis, we assessed the relationship between chronic levels of FOI and dialectical reasoning in Koreans. Consistent with our proposal, both experimentally primed FOI (Experiment 1A and 2) and chronic levels of FOI (Experiment 1B) were positively related to relative preference for dialectical proverbs. This effect was independent of participants’ level of negative mood (Experiment 2). A third experiment showed that sensitivity to context was affected by FOI in a manner consistent with previous studies of cultural differences (Experiment 3).     

Individual differences in information order effects: The importance of right-hemisphere access in belief updating

The order in which information is received alters the evaluation of causal hypotheses. Specifically, research suggests that the last piece of information oftentimes has the greatest impact on the evaluation and that the difference in subjective value between two pieces of information is an important factor influencing the magnitude of this recency effect. The present paper extends this line of work by exploring individual differences in this phenomenon via one's degree of handedness. Two hundred and five participants were given two hypothetical scenarios and related causal hypotheses accompanied by two pieces of additional information and asked to revise their belief in each hypothesis as information accumulated. Results confirmed predictions that 1) inconsistent/mixed-handers (those who use their non-dominant hand for at least some activities) show a larger effect with two pieces of inconsistent weak or strong information, and 2) neither mixed-handers nor consistent/strong-handers (those who use their dominant hand for almost all activities) show an effect with strong and weak pieces of consistent information. Mixed-handers' susceptibility to persuasive arguments and Ramachandran’s (1995; Ramachandran and Blakeslee, 1998) belief-updating theory centered around communication between the two halves of the brain and functional access to the right hemisphere are used to account for these data.     

Aging and strategic retrieval in a cued-recall test: the role of executive functions and fluid intelligence

Cued-recall in episodic memory was investigated in relation to low and high cognitive support at retrieval, executive function level and fluid intelligence level in 81 healthy adults divided first into two age groups (young and elderly adults). The first analyses showed that age-related differences were greater when a low cognitive support was provided to recall the words. An individual index of loss of performance when the number of cues was decreased was then calculated. Hierarchical regression analysis revealed that the executive functions measure (perseverative errors on the Wisconsin Card Sorting Test) was a better candidate than the fluid intelligence measure (Cattell's culture fair test) to account for the age-related variance of the size of performance loss. These findings suggest that age differences in implementing strategic retrieval may be mainly due to a decline in executive functions.     

An analogue study of the effects of Psychological Debriefing on eyewitness memory

Sixty-one participants from the community participated in a randomised controlled trial of group debriefing to assess the effect of this intervention upon memory for a stressful event. Participants were randomly allocated to one of three groups: debriefing; debriefing with an experimenter confederate present (who supplied three pieces of misinformation to the group regarding the stressful event); and a no-treatment control. All groups were shown a very stressful video and were again reviewed after 1 month. Members of the debriefing group where a confederate provided misinformation were more likely to recall this misinformation as fact than members of the other two groups. The debriefing group was also more accurate in their recall of peripheral content than the confederate group. Across all groups, participants were found to be more accurate at central rather than peripheral recall yet more confident for incorrect memories of the video than correct memories.     

Enhanced perceived responsibility decreases metamemory but not memory accuracy in obsessive-compulsive disorder (OCD)

Mixed findings have been obtained in prior research with respect to the presence and severity of memory and metamemory deficits in obsessive-compulsive disorder (OCD). We tested the hypothesis that experimentally induced increments of subjective responsibility would lead to a disproportionately strong decline of memory confidence and enhanced response latencies in OCD while leaving memory accuracy unaffected. Twenty-eight OCD patients and 28 healthy controls were presented a computerized memory test framed with two different scenarios. In the neutral scenario, the participant was requested to imagine purchasing 15 items from a do-it-yourself store. In the recognition phase, the 15 needed items were presented along with 15 distractor items. The participant was asked to decide whether items were on his or her shopping list or not, graded by subjective confidence. In the responsibility scenario, the general experimental setup was analogous except that the participant now had to envision that he or she was a helper in a region recently struck by an earthquake, dispatched to provide 15 urgently needed goods from a nearby town. In line with prior work by our group, samples did not differ in either condition on memory accuracy in a subsequent recognition task. As hypothesized, OCD participants were less certain in their responses for the high responsibility condition than controls. Whereas patients and controls did not differ in their subjective estimates for memorized items, patients expressed stronger doubt that their earthquake mission was successful. The findings indicate that low memory confidence in OCD may only be elicited in situations where perceived responsibility is high and that patients may share higher performance standards ("good is not good enough") than controls when perceived responsibility is inflated.     

Does providing props during preparation help children to remember a novel event?

We investigated the conditions under which preparatory information presented 1 day before a novel event influenced 6-year-olds' recall 1 week later. Children were assigned to one of six experimental conditions. Three conditions involved preparatory information that described the event accurately but differed according to the presence and type of props (verbal, real props, and toy props). In two conditions, which also differed according to whether verbal information was supplemented with real props, half of the preparatory information described the event accurately, whereas the other half was thematically similar to, but inconsistent with, the event (misleading verbal and misleading props). Compared with the attentional control condition, all forms of preparation that described the event accurately increased correct recall. Preparation that included props improved photograph recognition. When half of the accurate information was replaced by misleading information, the positive benefit on recall was reduced, and when misleading props accompanied the misleading information, errors increased. The potential underlying mechanisms and implications for pediatric settings are discussed.     

The development of memory for own- and other-race faces

This study demonstrates that experience and development interact to influence the "cross-race effect." In a multination study (n=245), Caucasian children and adults of European ancestry living in the United States, Norway, or South Africa, as well as biracial (Caucasian-African American) children and adults living in the United States, were tested for recognition of Asian, African, and Caucasian faces. Regardless of national or biracial background, 8- to 10-year-olds, 12- to 14-year-olds, and adults recognized own-race faces more accurately than other-race faces, and did so to a similar extent, whereas 5- to 7-year-olds recognized all face types equally well. This same developmental pattern emerged for biracial children and adults. Thus, early meaningful exposure did not substantially alter the developmental trajectory. During young childhood, developmental influences on face processing operate on a system sufficiently plastic to preclude, under certain conditions, the cross-race effect.