Individual,family, and societal dimensions of genetic discrimination: A case study analysis

Background. As the development and use of genetic tests have increased, so have concerns regarding the uses of genetic information. Genetic discrimination, the differential treatment of individuals based on real or perceived differences in their genomes, is a recently described form of discrimination. The range and significance of experiences associated with this form of discrimination are not yet well known and are investigated in this study. Methods. Individuals at-risk to develop a genetic condition and parents of children with specific genetic conditions were surveyed by questionnaire for reports of genetic discrimination. A total of 27,790 questionnaires were sent out by mail. Of 917 responses received, 206 were followed up with telephone interviews. The responses were analyzed regarding circumstances of the alleged discrimination, the institutions involved, issues relating to the redress of grievances, and strategies to avoid discrimination. Results. A number of institutions were reported to have engaged in genetic discrimination including health and life insurance companies, health care providers, blood banks, adoption agencies, the military, and schools. The alleged instances of discrimination were against individuals who were asymptomatic and sometimes impacted on other asymptomatic relatives. Few surveyed respondents knew of the existence of institutions such as state insurance commissions or the Medical Information Bureau, Inc., which may play roles in redress of grievances or correction of misinformation. Conclusions. Genetic discrimination is variable in form and cause and can have marked consequences for individuals experiencing discrimination and their relatives. The presence of abnormal genes in all individuals makes each person a potential victim of this type of discrimination. The increasing development and utilization of genetic tests will likely result in increased genetic discrimination in the absence of contravening measures. All authors contributed equally to this work. This work was supported by a grant from the U.S. Department of Energy and funding from the Department of Mental Retardation of the Commonwealth of Massachusetts.     

Increasing achievement motivation and work productivity in a chronic psychiatric population

The major goal of this study was to determine if social reinforcement for behavior in a simulated work activity would increase achievement motivation, work interest, and simulated work activity production. Forty-five chronic psychiatric patients were randomly assigned to one of three groups: work sample with praise, work sample without praise, and a no-treatment control group. A 3 (between) × 2 (within) analysis of variance was run for each dependent measure, that is, achievement imagery, work interests, and simulated work production. The main effect for the interaction between trials and treatment was significant on each dependent measure. Follow-up Duncan Multiple Range Tests indicated that the praise group showed a significant improvement on each dependent measure, pre to post, as well as significantly greater improvement than the no-treatment control group and/or the work sample without praise group. These results are discussed in terms of the procedure used as a method for increasing motivation and in terms of possible generalization of results to other treatment situations.     

Memory and personality: An information processing approach

A consensual model of memory, based on information processing theory is presented. The experimental literature on the interaction between memory and personality is reviewed in terms of this model. It is suggested that past study in this area has failed to utilize the knowledge and techniques of information processing theory, and as a result, has confounded experimental variables. Suggestions for more appropriate research are presented.     

Novelty as a reinforcer for position learning in children

The stimulus-familiarization-effect (SFE) paradigm, a reaction-time (RT) task based on a response to novelty procedure, was modified to assess response for novelty, i.e., a response-reinforcement sequence. Ninetysix kindergarten children were familiarized on one of two colored lights. Then Ss were confronted with a simple position discrimination task in which they could choose between two response buttons which produced either the previously familiarized light or a new (i.e., novel) light. Results showed that the choice response for the novel stimulus (NS) was facilitated by three variables: number of exposures to and duration per exposure of the familiar stimulus (FS), and degree of change provided by the NS relative to the FS. The parallel between the effective variables of this study and those which produce the SFE was noted, implicating an attention interpretation of the function of novelty as a reinforcer. The potential implications of attention for reinforcement theory and learning in general are discussed.     

Behavior therapy for obesity: Booster sessions and long-term maintenance of weight loss

Following 8 weekly sessions of group behavioral self-control treatment, 75 obese women were assigned to one of five different maintenance conditions: (a) structured behavioral booster sessions held every two weeks; (b) structured behavioral booster sessions held every month; (c) unstructured nonspecific booster sessions held every two weeks; (d) unstructured nonspecific booster sessions held every month; and (e) a control group that received no booster sessions. Follow-ups were conducted at 3, 6, 9 and 12 month intervals. The study was completed in two replications. Results failed to show a significant effect of either booster session content or frequency. All groups continued to lose weight during the first three months of follow-up. Thereafter subjects in Replication 1 showed significant increases in weight over the next 9 months, whereas subjects in Replication 2 maintained their treatment-produced weight loss. The data do not support the view that booster sessions facilitate maintenance.     

Nature of spelling errors in transcortical sensory aphasia: A case study

The nature and extent of spelling errors in a patient with transcortical sensory aphasia were investigated. The two experimental conditions required the patient to spell monosyllabic and polysyllabic words both verbally and in written form. Analysis of the spelling errors revealed partially preserved knowledge of the visual image of a word as a whole, as well as preserved knowledge of temporal order. Our patient's error patterns in both conditions were more similar than dissimilar. These findings in conjunction with results reported in the literature indicate that patients exhibiting different aphasia syndromes use separate spelling strategies.     

Concerning Hunt's new ways of assessing intelligence

Hunt envisions the automation of intelligence testing (Intelligence, 1982, 6, 231–240), but he appears to be overly optimistic. He neglects to mention conceptual and practical difficulties at the interface of measurement and theory that place psychometry not in the dawn of microcomputerization, but rather more nearly in its primordium.