Functional cerebral changes in multiple sclerosis patients during an autobiographical memory test

Our aim was to investigate the functional underpinnings of autobiographical memory (AM) impairment in multiple sclerosis (MS) patients. To that end, 18 patients and 18 controls underwent the autobiographical interview (AI). Subsequently, the 36 participants underwent a functional magnetic resonance imaging (fMRI) session designed to assess the construction and elaboration of AMs. A categorical control task was also presented. Patients were trained in the fMRI procedure to optimise the procedural aspects accompanying the task itself. Although the patients obtained significantly poorer AI scores (p < .001), their performance on the easier AM fMRI task was efficiently carried out, allowing relevant comparisons with healthy controls. Relatively to healthy controls, the patients showed increased and bilateral cerebral activations (p < .005) during the construction and elaboration phases. The prefrontal, temporal and posterior cerebral region activations were located within the core network sustaining AM, with the bilateral prefrontal region being centrally involved. The parametric neural responses to the difficulty of access and amount of details of memories were also significantly different for the two groups, with the right hippocampal region showing a particularly increased recruitment (p < .005). The findings suggested the presence of functional cerebral changes during AM performance and supported the presence of AM retrieval deficit in MS patients.     

The Significance of Ferenczi's clinical contributions for working with psychotic patients

This paper tries to show that Ferenczi's contributions in “The Development of Psychoanalysis” (with Otto Rank) and in his “Clinical Diary” are pivotal for the development of modern psychotherapy with severely disturbed patients. In addition, the question of whether a psychotherapeutic technique should or could be communicated to others is discussed.     

AGNOSTIC MEDITATIONS ON BUDDHIST MEDITATION

I first attempt a taxonomy of meditation in traditional Indian Buddhism. Based on the main psychological or somatic function at which the meditative effort is directed, the following classes can be distinguished: (1) emotion‐centered meditation (coinciding with the traditional samatha approach); (2) consciousness‐centered meditation (with two subclasses: consciousness reduction/elimination and ideation obliteration); (3) reflection‐centered meditation (with two subtypes: morality‐directed reflection and reality‐directed observation, the latter corresponding to the vipassanā method); (4) visualization‐centered meditation; and (5) physiology‐centered meditation. In the second part of the essay I tackle the problem of the epistemic validity and happiness‐engendering value of Buddhist meditation. In my highly conjectural view, the claim that meditation represents an infallible tool for realizing the (Supreme) Truth as well as a universally valid method for attaining the highest forms of happiness is largely based on the crēdō effect, that is, a placebolike process. I do not deny that meditation may have some positive effects on mental and physical health or that its practice may bring changes to the mind. Meditation may be a valuable alternative approach in life and clinical treatment, but it is far from being a must or a panacea.     

高中生英语阅读知觉广度的眼动研究

该研究采用经典的"呈现随眼动变化技术"对高中生的英语阅读的知觉广度进行了眼动研究。结果发现:1)高中生英语阅读知觉广度的右侧范围是注视点右侧8～11个字符的空间;2)高中生的英语阅读知觉广度已达到成人水平。     

小学五年级学生英语阅读知觉广度的眼动研究

使用Eyelink2000型眼动仪,采用经典的呈现随眼动变化技术,对24名被试在不同窗口条件下英文阅读的眼动指标进行记录和分析,以考察小学五年级学生英语阅读的知觉广度。研究结果表明:小学五年级学生英语阅读的知觉广度的右侧范围是注视点右侧5-8个字符空间。     

Left orbital frontal activation in pathological anxiety

Twelve patients with anxiety disorder were studied with respect to regional cerebral blood flow (rCBF) using a 32-detector system with the 133 Xe inhalation technique. Measurements were taken during a rest condition and during anxiety induction. Anxiety relevant to the patient's psychological disorder was induced with a projective test, the meta-contrast technique (MCT). Increased blood flow in the orbital frontal region of the left hemisphere was observed in each of the 11 subjects who showed evidence of experiencing anxiety during the procedure. In a second study four additional anxiety patients were studied with a high-resolution (254-detector)Xe rCBF system. In addition to the anxiety and resting conditions, a neutral verbalization condition was added to control for the verbal aspects of the anxiety induction procedure. The results again showed the experience of anxiety to be accompanied by increased blood flow in the left orbital frontal region, with the patients showing this flow increase to be greater in the posterior, paralimbic, areas of the region. These results are consistent with previous suggestions of left hemisphere involvement in anxiety. They also suggest that imaging methods may allow research into what appears to be exaggerated corticolimbic activity in this disorder.     

Functions of parahippocampal place area and retrosplenial cortex in real-world scene analysis: An fMRI study

We used functional MRI to investigate several hypotheses concerning the functions of posterior parahippocampal cortex and retrosplenial cortex, two regions that preferentially activate to images of real-world scenes compared to images of other meaningful visual stimuli such as objects and faces. We compared activation resulting from photographs of rooms, city streets, cityscapes, and landscapes against activation to a control condition of objects. Activation in posterior parahippocampal cortex, including parahippocampal place area, was greater for all scene types than objects, and greater for scenes that clearly convey information about local three-dimensional (3-D) structure (city streets and rooms) than scenes that do not (cityscapes and landscapes). Similar differences were observed in retrosplenial cortex, though activation was also greater for city streets than rooms. These results suggest that activation in both cortical areas is primarily related to analysis or representation of local 3-D space. The results are not consistent with hypotheses that these areas reflect panoramic spatial volume, an artificial versus natural category distinction, an indoor versus outdoor distinction, or the number of explicit objects depicted in a scene image.     

认知地图技术及其在管理心理学中的应用述评

认知地图技术是用来获取个体对某个特定领域独特理解的图形化描述的一系列方法的总称,包括认知诱发技术与分析技术.在详细阐述其概念、原理的基础上,本文结合一个共享心智模型的研究实例,展示了认知地图技术应用的一般步骤.然后,介绍了认知地图技术在管理心理学中的应用.并针对认知地图技术存在的问题,对未来的研究进行了展望,即从认知地图技术的理论、应用及软件等方面开展深入研究.     

追踪研究中缺失数据处理方法及应用现状分析

追踪研究中普遍存在缺失数据, 缺失数据处理方法的选择影响统计推断的精度及研究结果的有效性。首先, 阐述缺失机制及判断方法, 比较追踪研究中主要的缺失数据处理方法的特点、及实际应用中的缺失处理方法的选择和软件实现。其次, 对国内心理学中92篇追踪研究文献进行分析, 发现有59篇(64.13%)报告不同程度缺失, 其中仅39篇报告了处理方法且均为删除法。未来研究应深入探讨现有缺失数据处理方法的有效性, 进一步规范应用研究中缺失数据的处理。