Numerical taxonomy of aphasia

Two hundred consecutively seen aphasics, 142 of them with infarcts, were examined by tests of fluency, comprehension, repetition, naming, and information content. The language scores were subjected to a minimum variance clustering algorithm separately for the total and for the infarct groups. The latter generated 10 clusters on a dendrogram. Attribute analysis of each cluster provided a clinically meaningful profile of language performance for these groups. The degree of correlation of most computer generated clusters with clinically recognized groups was high, and the homogeneity of some of the clusters is striking. An exception appears to be “conduction aphasia,” which is bimodally distributed. One of these clusters, with high fluency and low comprehension scores, was renamed “afferent conduction” aphasia, and the other, with lower fluency and higher comprehension, was renamed “efferent conduction” aphasia. The Principal Components Analysis was used to evaluate the discriminatory value of language characteristics, and the Nearest Neighbor Network Analysis was used to evaluate the significance of clustering. The dendrogram for all aphasics showed a less specific and less homogenous six clusters.     

Dissociable stages of problem solving (II): first evidence for process-contingent temporal order of activation in dorsolateral prefrontal cortex

In a companion study, eye-movement analyses in the Tower of London task (TOL) revealed independent indicators of functionally separable cognitive processes during problem solving, with processes of building up an internal representation of the problem preceding actual planning processes. These results imply that processes of internalization and planning should also be distinguishable in time and space with respect to concomitant brain activation patterns. To investigate this possibility, here we conducted analyses of fMRI data for left and right dorsolateral prefrontal cortex (dlPFC) during problem solving in the TOL task by accounting for the trial-by-trial variability of onsets and durations of the different cognitive processing stages. Comparisons between stimulus-locked and response-locked modeling approaches affirmed that activation in left dlPFC was elicited particularly during early processes of internalization, comprising the extraction of goal information and the generation of an internal problem representation, whereas activation in right dlPFC was predominantly attributable to later processes of mental transformations on this representation, that is planning proper. Thus, present data corroborate the proposal that often observed bilateral dlPFC activation patterns during complex cognitive tasks such as problem solving may reflect functionally and, to some extent, even temporally separable processes with opposing lateralizations.     

Dissociable stages of problem solving (I): temporal characteristics revealed by eye-movement analyses

Understanding the functional neuroanatomy of planning and problem solving may substantially benefit from better insight into the chronology of the cognitive processes involved. Based on the assumption that regularities in cognitive processing are reflected in overtly observable eye-movement patterns, here we recorded eye movements while participants worked on Tower of London (TOL) problems that comprised an experimental manipulation of different task demands. Single-trial saccade-locked analyses revealed that higher demands on forming an internal problem representation were associated with an increased number of gaze alternations between start state and goal state, but did not show any effect on the durations of these inspections of the states. In contrast, higher demands on actual planning in terms of mental manipulations of working memory contents coincided with a prolonged duration of the very last inspection of the start state (i.e., immediately preceding movement execution) but did not show any effect on the number of gaze alterations. Differential task demands on internalization and planning processes during problem solving hence selectively affect different eye-movement parameters. Moreover, these findings complement previous neuroimaging data on dissociable contributions of left and right dorsolateral prefrontal cortex in problem solving with novel evidence for a corresponding dissociation in the eye-movement patterns reflecting the associated cognitive processes.     

Affect,infrastructure and activism: The House of Brag's London Queer Social Centre in Brixton,South London

The House of Brag was a queer, anti-racist, feminist squatting collective active between 2012 and 2014. This article pieces together an affective and infrastructural geography of the House of Brag's last project: a squatted social centre in Brixton, south London, in the summer of 2014. Drawing on interviews with members of the collective, this article argues that efforts to think and live social and political alternatives – and the affective dimensions of these efforts – cannot be abstracted from their infrastructures. The material space and infrastructure of the squatted social centre, this article contends, shaped the House of Brag's dynamics and work in crucial ways. In foregrounding these issues, this article contributes to literature on geographies of affect, emotions and social movements, in which conflict and ‘negative’ affects and emotions are often minimised, and which largely overlook the complex material geographies of spaces of activism. In exploring a queer, anti-racist, feminist squatted project in 2010s London, this article also contributes to literature on squatting by focusing on a time period, on politics and on locations largely overlooked.     

Looking ahead from age 6 to 13: A deeper insight into the development of planning ability

Planning ability gradually increases throughout childhood. However, it remains unknown whether this is attributable to global factors such as an increased ability and willingness to inhibit premature, impulsive responding, or due to the availability of specific planning operations, such as being able to mentally plan ahead more steps (‘search depth’) or to derive a clear temporal order of goals by the task layout (‘goal hierarchy’). Here, we studied the development of planning ability with respect to these global and problem‐specific aspects (search depth and goal hierarchy) of performance in 178 children from 6 to 13 years using the Tower of London task. As expected, global performance gradually developed with age. In accordance, planning durations increasingly reflected global problem demands with longer pre‐planning in harder problems. Furthermore, specific planning parameters revealed that children were increasingly capable of mentally searching ahead more steps. In contrast, the ability to derive a goal hierarchy did not show age‐related changes. While the global development of planning performance and adaptive planning durations were proposed to primarily reflect enhanced self‐monitoring, the specific increase in search depth across childhood that most likely proceeds until young adult age represents more directly planning‐related processes. Thus, development of planning ability is supported by multiple contributions.     

Tyndale's Disagreement with Luther in the Prologue to the Epistle to the Romans

Abstract

Although it is generally assumed that Tyndale's Prologue to the Epistle to Romans (1526) is a translation of Luther's Preface (1522), this article examines those places where Tyndale deviated from a straight translation of Luther's text, and supports Thomas More's statement that Tyndale was a worse heretic than Luther. Tyndale's doctrine of God, the Father, Christ, and especially of the Holy Spirit, faith, righteousness, flesh and spirit, the state of fallen man and the temporal regiment show Tyndale was not doctrinally a Lutheran when he wrote his Prologue to Romans.     

Robert Singleton's Sermon at Paul's Cross in 1535: The ‘True Church’ and the Royal Supremacy

Abstract

On 2 April 1535, Robert Singleton, chaplain to Queen Anne Boleyn, preached a sermon at Paul's Cross. The unique, surviving printed copy of the sermon is housed in the Wren Library of Lincoln Cathedral. From 1533, Singleton had been a member of the circle of avant-garde evangelicals gathered at the margins of the Tudor court under the patronage of Thomas Cromwell. His sermon at Paul's Cross contributed to an orchestrated campaign in support of Cromwell's legislative programme, then proceding through Parliament, to sever all links of ecclesiastical jurisdiction with Rome and to confirm Henry's headship of the Church of England. The sermon interprets Paul's allegory of the earthly and the heavenly Jerusalem in the Epistle to the Galatians as a model for thinking about the distinction between the invisible and visible Church. Singleton harnesses Pauline ecclesiology in an apology for the royal supremacy. Presented here is a transcribed copy of the original printed version.     

Roe's classification and the multidimensional nature of occupational perception

The purpose of this study was to compare college students' perceptions of the similarity of occupations with the groupings suggested by Roe (1956). Subjects were 90 male and 99 female university freshmen. Four illustrative titles were selected from five of Roe's eight groups. Subjects were asked to judge the similarity of each of the possible pairs of titles. The results were analyzed using multidimensional scaling procedures. The data provide partial support for Roe's postulated structure, although the subject's perceptions were generally more complex than suggested by Roe. In particular, the hypothesized circumplex arrangement of groups received only limited support.     

Establishing discriminative stimulus control within generalized oddity performance,without reinforcement

In two oddity learning studies with children, subjects were reinforced for oddity (or nonoddity) responding on line-tilt or dot numerosity problems. Interposed form and color problems were not reinforced. No instructions to make oddity choices were given. In Experiment I it was found that reinforcement for oddity or nonoddity responding on tilt and numerosity problems produced the corresponding tendency toward oddity or nonoddity performance on these problems and also on the nonreinforced form and color problems. These results show a generalized oddity phenomenon similar to generalized imitation. In Experiment II a third type of nonreinforced problem was presented in this same format: compound stimuli permitting either a color or a form solution. It was found that immediate prior training with nonreinforced form problems, interpolated among the reinforced tilt and numerosity problems, led to form-oddity choices in the compound problems. Similarily, color pretraining produced color-oddity choices. These results show that selective discriminative stimulus control can be obtained in oddity learning, without reinforcement for choices on either of the two dimensions involved.