轻度认知功能障碍患者工作记忆中 脑电能量及皮质联络功能的变化特征

探讨轻度认知功能障碍患者（MCI）工作记忆状态下脑电能量及皮质联络功能的变化特征。被试为从社区选取的35名轻度认知功能障碍患者和34名健康志愿者。采用简单计算回忆方法,结果发现工作记忆加工过程中会引起4.0~18.0Hz范围内功率值的改变,且MCI组高于正常对照组;MCI患者在中央、顶、颞叶的半球间相干系数均显著高于正常对照组。研究结果提示MCI患者可能存在中央、顶、颞叶皮层的功能减退,工作记忆状态下通过代偿机制仍能维持加工的有效性     

司法论证充分性辨析

司法论证充分性问题是一个和法学理论与司法实践都密切相关的问题,各种关于法律论证的争议是和规则治理与纠纷解决两种司法职能的互相冲撞息息相关的。什么样的法律论证才是最合适的,在法律资源有限的情况下,如何运用有限的资源达到司法实践的目的,是各国法制建设的一个永恒话题。文章试图以我国的司法情景为例,从理性思考与现实实践两个层面,展示法官在裁决中所运用的具有地方性知识性质的辅助资源具有实践合理性,说明司法论证应该也必须追求其充分性。     

Living with Multiple Endocrine Neoplasia Type 1: Decent Care-Insufficient Medical and Genetic Information A Qualitative Study of MEN 1 Patients in a Swedish Hospital

This qualitative study explores how 29 Swedish patients with Multiple Endocrine Neoplasia type 1 (MEN1) experience living with the condition, appraisal of the clinical follow-up program, and surveys their future expectations. The aim of this study is to build knowledge about this patient group in order to provide optimal care. The participants describe physical, psychological, and social limitations in their daily activities and how these limitations influence quality of life. Our findings indicate that a majority of patients have adjusted to their situation, describing themselves as being healthy despite physical symptoms and treatment. The participants received decent care in the clinical follow-up program, - however, greater effort should be put into patient information. These patients might benefit from genetic counseling. Health professionals involved should recognize their potential impact and influence on a patient’s ability to adjust to these circumstances. Antonovsky`s Sense of Coherence theory is used to discuss these findings.     

The Influence of Cancer-related Distress and Sense of Coherence on Anxiety and Depression in Patients with Hereditary Cancer

This study examines the association between Sense of Coherence and anxiety and depression amongst patients at risk of hereditary cancer receiving genetic counseling. When writing this article, 144 patients referred for genetic counseling due to a suspicion of hereditary cancer in the family were recruited for this multicentered longitudinal study on the psychosocial aspects of genetic counseling in Norway. A total of 96 (66%) patients responded to the follow-up survey distributed 6 months after genetic counseling. This survey included the Sense of Coherence-29 Scale, Impact of Event Scale, and Hospital Anxiety and Depression Scale. Multiple regression analyses were applied. Our results show association between cancer-related distress and symptoms of anxiety and depression. Sense of Coherence is significantly associated with both anxiety and depression. The hypothesis of Sense of Coherence buffering cancer-related distress and the possible impact of these findings for genetic counseling are discussed.     

Preference for impossible figures in 4-month-olds

Can infants use interposition and line junction cues to infer three-dimensional (3D) structure? Previous work has shown that in a task that required 4-month-olds to discriminate between static two-dimensional (2D) pictures of possible and impossible cubes, infants exhibited a spontaneous preference for displays of the impossible cube but left open the question of whether they did so on the basis of purely local “critical regions” or whether they were able to employ more global clues. Here infants were presented with possible and impossible cubes in which the strictly local cues that could have derived from exterior binding contours were deleted. Results showed that infants were still able to discriminate possible cubes from impossible cubes, suggesting that longer looking infants are sensitive to global properties and that the capacity to integrate pictorial information to perceive aspects of global 3D shape may develop earlier than demonstrated previously using reaching tasks.     

The Effects of Thematic Importance on Story Recall among Children with Attention Deficit Hyperactivity Disorder and Comparison Children

This study examined the recall of televised stories for younger (4-6 years) and older (7-9 years) children with and without attention deficit hyperactivity disorder (ADHD) under two different viewing conditions (toys present/toys absent). Each child watched two Rugrats television programs, once with toys present and once with toys absent. Immediately after viewing a program, the child completed a free recall of the observed story. Comparison children's recall increased more than ADHD children's as importance level increased, and comparison children recalled more information overall than children with ADHD. When toys were present, children with ADHD retold less coherent stories than comparison children, as indexed by smaller correlations between the story units recalled and the order of these units in the story. In summary, children with ADHD demonstrated multiple difficulties in story comprehension. These findings add to our understanding of the differences in higher-order cognitive processing abilities between children with ADHD and comparison children, and suggest important areas of focus in designing more effective academic interventions for children with ADHD.     

The coherence of memories for trauma: Evidence from posttraumatic stress disorder

Participants with posttraumatic stress disorder (PTSD) and participants with a trauma but without PTSD wrote narratives of their trauma and, for comparison, of the most-important and the happiest events that occurred within a year of their trauma. They then rated these three events on coherence. Based on participants’ self-ratings and on naïve-observer scorings of the participants’ narratives, memories of traumas were not more incoherent than the comparison memories in participants in general or in participants with PTSD. This study comprehensively assesses narrative coherence using a full two (PTSD or not) by two (traumatic event or not) design. The results are counter to most prevalent theoretical views of memory for trauma.     

Salutogenesis and autobiographical disclosure among Holocaust survivors

Forty-five Holocaust survivors and a comparison group of 21 Jews who had not experienced Nazi persecution completed questionnaires assessing salutogenic (health-enhancing) and pathogenic (illness-inducing) outcomes of Holocaust vs. other traumatic experiences. Salutogenesis and pathogenesis were negatively correlated. Holocaust survivors were consistently higher on the measure of salutogenesis; with marital history held constant, this difference was statistically significant. Neither group reported high incidences of posttraumatic stress symptoms, although survivors reported more. Talking about one's Holocaust experiences was related to more positive and fewer negative responses. Marital history and religious observance mediated some aspects of both positive and negative long-term consequences. The results indicate that the long-term consequences of even extreme trauma may include increased personal strength and growth.     

Maturity is coherent: Structural and content-specific coherence in adolescent moral identity

Identity narrative may involve considerable variations in structural and content-specific coherence. These variations are potentially relevant to the development of moral commitment in adolescence. The present study analyzed coherence in moral identity narratives for a matched comparison sample of urban adolescents. Thirty nominated adolescent moral exemplars and 30 everyday comparators were given interview prompts designed to tap identity narrative. Structural and content-specific coherence dimensions were assessed with a palette of computational techniques known as coh-metrix. Consistent with study hypotheses, exemplar adolescent moral identity narratives generally evinced greater structural and content-specific coherence than everyday comparators, particularly on causality and agentic intentionality dimensions. Findings suggest that moral identity coherence is a kind of expertise fixed in developmental processes and associated with real-world action.