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191.
Qiu S Korwek KM Pratt-Davis AR Peters M Bergman MY Weeber EJ 《Neurobiology of learning and memory》2006,85(3):228-242
The heterozygote reeler mouse (HRM) shows many neuroanatomical and biochemical features that are also present in some human cognitive disorders, such as schizophrenia. In the present study, hippocampal dependent plasticity and cognitive function of the HRM were characterized in detail in an attempt to reveal phenotypic functional differences that result from Reelin haploinsufficiency. The HRM and wild type mice show similar levels of overall activity, coordination, thermal nociception, startle responses, and anxiety-like behavior. In addition, both genotypes show similar shock threshold, identical cued freezing behavior and comparable spatial learning in Morris water maze tasks. However, a significant reduction in contextual fear conditioned learning was observed in the HRM. Electrophysiological studies in hippocampal CA1 synapses revealed a plethora of differences between genotypes. The HRM exhibits reduced field excitatory postsynaptic potentials in responses to similar synaptic inputs, lowered paired pulse facilitation ratio and impaired long-term depression and tetanus-induced long-term potentiation (LTP). Also, deficits were detected in LTP elicited by theta burst stimulation or by a whole cell pairing protocol. These physiologic differences could not be accounted for by changes in the overall amount of glutamate receptor subunits. In addition, it was determined that network-driven excitatory and inhibitory activities recorded in CA1 pyramidal neurons showed that the HRM had comparable amplitude and frequency of spontaneous excitatory postsynaptic currents, but a marked reduction in spontaneous inhibitory postsynaptic currents. Thus, the HRM exhibits a specific hippocampal-dependent learning deficit accompanied with a pronounced impairment of hippocampal plasticity and functional inhibitory innervation. 相似文献
192.
Glenn J. Browne Mitzi G. Pitts 《Organizational behavior and human decision processes》2004,95(2):208-224
Information search is critical in most decision-making tasks. An important aspect of information search is the stopping rule used by the decision maker to terminate information acquisition. Decision-making problems may be usefully decomposed into design problems and choice problems. The distinction is critical because the goals of stopping behavior in the two types of problems are quite different. In design problems, the focus is on the sufficiency of information obtained for problem structuring and generating alternatives, while choice problems focus on convergence toward a solution. While previous research has studied stopping behavior in choice problems, the present research is concerned with stopping rule use during information search in design problems. To build theory in this area, we conducted two experiments. In the first, we presented professional systems analysts with an information search problem in a systems development context and asked them to gather information for a proposed system. Protocols of the search sessions were analyzed, and stopping rules used and information gathered by the analysts were identified. Results indicated that the use of certain stopping rules resulted in greater quantity and quality of information gathered. Additionally, stopping rule use, rather than analyst experience, accounted for the quantity and quality of information elicited. Finally, stopping rule use differed between more experienced and less experienced analysts. To apply our findings about stopping rules from the first experiment, we performed a second experiment in which we investigated stopping rule use in a consumer information search task on the world wide web. Results indicated the use of the same stopping rules as in the first experiment, although in different proportions. Implications for information search theory and practice are discussed. 相似文献
193.
Recent work has demonstrated that performance on a simultaneous target-present photographic line-up can be enhanced by prior global processing orientation, and hindered by prior local processing orientation induced by processing Navon letter stimuli. A series of studies explore the generality of this processing bias effect using either videotaped scenarios or live interactions. Five experiments demonstrate that these effects are seen across a range of test stimuli, test formats, and test instructions. These data inform the processes engaged in by witnesses when making line-up identifications and indicate that it may be possible to improve the accuracy of witnesses making such judgements. 相似文献
194.
Since the 1970s there has been a continuing interest in how people recognise familiar faces (Bruce, 1979; Ellis, 1975). This work has complemented investigations of how unfamiliar faces are processed and the findings from these two strands of research have given rise to accounts that propose qualitatively different forms of representation for familiar and unfamiliar faces. Evidence to suggest that we process familiar and unfamiliar faces in different ways is available from cognitive neuropsychology, brain scanning, and psychophysics. However, in this review we focus on the evidence, available from experimental investigations of how people recognise faces, for different types of representation existing for each type of face. Factors affecting recognition are evaluated in terms of how they apply to familiar and unfamiliar faces and categorised according to the nature of their impact. In the final section this evidence, along with recent advances in the field, is used to explore the way in which unfamiliar faces may become familiar and the factors that may be important for the development of familiar face representations. 相似文献
195.
Louis A. Penner Nao Hagiwara Susan Eggly Samuel L. Gaertner Terrance L. Albrecht John F. Dovidio 《European Review of Social Psychology》2013,24(1):70-122
Around the world, members of racial/ethnic minority groups typically experience poorer health than members of racial/ethnic majority groups. The core premise of this chapter is that thoughts, feelings, and behaviours related to race and ethnicity play a critical role in healthcare disparities. Social psychological theories of the origins and consequences of these thoughts, feelings, and behaviours offer critical insights into the processes responsible for these disparities and suggest interventions to address them. We present a multilevel model that explains how societal, intrapersonal, and interpersonal factors can influence ethnic/racial health disparities. We focus our literature review, including our own research, and conceptual analysis at the intrapersonal (the race-related thoughts and feelings of minority patients and non-minority physicians) and interpersonal levels (intergroup processes that affect medical interactions between minority patients and non-minority physicians). At both levels of analysis, we use theories of social categorisation, social identity, contemporary forms of racial bias, stereotype activation, stigma, and other social psychological processes to identify and understand potential causes and processes of health and healthcare disparities. In the final section, we identify theory-based interventions that might reduce ethnic/racial disparities in health and healthcare. 相似文献
196.
Heather Harris Wright Anthony D. Koutsoftas Gilson J. Capilouto Gerasimos Fergadiotis 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2014,21(2):174-196
The purpose of the present research was to examine the influence of cognitive processes on discourse global coherence ability measured across different discourse tasks and collected from younger (n = 40; 20–39 years) and older (n = 40; 70–87 years) cognitively healthy adults. Study participants produced oral language samples in response to five commonly used discourse elicitation tasks and they were analyzed for maintenance of global coherence. Participants also completed memory and attention measures. Group differences on the global coherence scale were found for only one type of discourse—recounts. Across discourse elicitation tasks the lowest global coherence scores were found for recounts compared to the other discourse elicitation tasks. The influence of cognitive processes on maintenance of global coherence differed for the two age groups. For the younger group, there were no observed significant relationships. For the older group, cognitive measures were related to global coherence of stories and procedures. 相似文献
197.
Dario D. Salvucci 《Cognitive Science》2013,37(5):829-860
Previous accounts of cognitive skill acquisition have demonstrated how procedural knowledge can be obtained and transformed over time into skilled task performance. This article focuses on a complementary aspect of skill acquisition, namely the integration and reuse of previously known component skills. The article posits that, in addition to mechanisms that proceduralize knowledge into more efficient forms, skill acquisition requires tight integration of newly acquired knowledge and previously learned knowledge. Skill acquisition also benefits from reuse of existing knowledge across disparate task domains, relying on indexicals to reference and share necessary information across knowledge components. To demonstrate these ideas, the article proposes a computational model of skill acquisition from instructions focused on integration and reuse, and applies this model to account for behavior across seven task domains. 相似文献
198.
Sonia Gojman de Millán Ph.D. Salvador Millán 《International Forum of Psychoanalysis》2013,22(4):254-263
We present a study of 40 youngsters who live and work in the streets of Mexico City and who have abandoned their homes for significant periods of time. They seek out their own means of survival from a very young age. In many cases they have children of their own already as teenagers. The Seminario de Sociopsicoanálisis was invited to take part in a project aimed at facilitating the access of these children to graphic arts, artistic creation and therapeutic listening. This article presents our principal findings of the children's everyday life conditions, their work and their dreams, based on data obtained from social character questionnaires – with which therapeutic intervention in this project began. Vignettes of two case studies are also presented. The interviews were complemented by data gathered in weekly sessions attended by the youngsters on a voluntary bases. The sessions attested to both the narcissistic, aggressive impulsiveness of these youngsters and the vital effort they make toward their own recovery and toward establishing affective emotional ties with instructors and therapists. We found that socio‐psychoanalytic methods could be used successfully to expand the scope of psychoanalytic theoretic postulates about character to a non‐clinical, disadvantaged population. By analyzing the content of the psychoanalytically guided interviews we were able to recognize the central, distinctive motive, which leads these youngsters to run away from home and forge their own sense of identity. 相似文献
199.
Marloes Kleinjan Regina J. J. M. van den Eijnden Jan van Leeuwe Johannes Brug Monique O. M. van de Ven Rutger C. M. E. Engels 《Psychology & health》2013,28(6):729-743
The present study addresses the applicability of the Transtheoretical Model's processes of change in explaining adolescents’ readiness to quit smoking. Furthermore, the association between nicotine dependence and readiness to quit was assessed both directly, as well as indirectly through the processes of change. A cross-sectional survey was conducted, identifying 1547 weekly smokers aged 14–18 years. Structural equation modelling showed that the processes of change were only marginally associated with readiness to quit. Adding nicotine dependence to the model showed a direct association between nicotine dependence and readiness to quit. Only one process of change, self-liberation (i.e. choice/commitment to change and belief in the ability to change), was found to mediate this association. Nicotine dependence appeared to be highly important in adolescents’ readiness to quit. 相似文献
200.
This study assessed the unique associations of risk perceptions and worry with attitudes about genetic testing for breast cancer susceptibility. Women (general practitioner clinic attenders, university students, and first-degree relatives of breast cancer survivors; N?=?303) read information about genetic testing and completed measures assessing perceived cancer risk, cancer worry, and genetic testing attitudes and beliefs. Worry was associated with greater interest in genetic testing, stronger beliefs that testing has detrimental emotional consequences, and positive beliefs about benefits of testing and risk-reducing surgeries. Perceived risk was unrelated to interest and associated with more skeptical beliefs about emotional consequences and benefits of testing and risk-reducing surgeries. At low worry levels, testing interest increased with more positive beliefs about testing benefits; at high worry levels, interest was high regardless of benefits beliefs. The findings support Leventhal's Common-Sense Model of self-regulation delineating interactive influences of risk-related cognitions and emotions on information processing and behavior. 相似文献