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161.
Using data from samples of 300 and 220 adoptive families from the Texas Adoption Project, aspects of generality of a “General Factor of Personality” (GFP) were examined: across different personality inventories, across different levels of analysis (items, scales) within an inventory, across self- and others’ judgments, and across sexes, ages, and generations. Considerable, though not complete, generality was found. The average correlation between GFPs from items and scales of a given inventory was .90; between GFPs from the scales of different inventories was .48. Also examined were the heritability of a GFP, its degree of correlation with a general cognitive factor, and its ability to predict real-life criteria such as educational level, marital stability, and substance abuse. 相似文献
162.
Bilingual speakers generally manifest slower word recognition than monolinguals. We investigated the consequences of the word processing speed on semantic access in bilinguals. The paradigm involved a stream of English words and pseudowords presented in succession at a constant rate. English-Welsh bilinguals and English monolinguals were asked to count the number of letters in pseudowords and actively disregard words. They were not explicitly told that pairs of words in immediate succession were embedded and could either be semantically related or not. We expected that slower word processing in bilinguals would result in semantic access indexed by semantic priming. As expected, bilinguals showed significant semantic priming, indexed by an N400 modulation, whilst monolinguals did not. Moreover, bilinguals were slower in performing the task. The results suggest that bilinguals cannot discriminate between pseudowords and words without accessing semantic information whereas monolinguals can dismiss English words on the basis of subsemantic information. 相似文献
163.
We assessed the relationship between brain structure and function in 10 individuals with specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated control participants with typical language. Voxel-based morphometry indicated that grey matter in the SLI group, relative to controls, was increased in the left inferior frontal cortex and decreased in the right caudate nucleus and superior temporal cortex bilaterally. The unaffected siblings also showed reduced grey matter in the caudate nucleus relative to controls. In an auditory covert naming task, the SLI group showed reduced activation in the left inferior frontal cortex, right putamen, and in the superior temporal cortex bilaterally. Despite spatially coincident structural and functional abnormalities in frontal and temporal areas, the relationships between structure and function in these regions were different. These findings suggest multiple structural and functional abnormalities in SLI that are differently associated with receptive and expressive language processing. 相似文献
164.
Petitto LA Berens MS Kovelman I Dubins MH Jasinska K Shalinsky M 《Brain and language》2012,121(2):130-143
In a neuroimaging study focusing on young bilinguals, we explored the brains of bilingual and monolingual babies across two age groups (younger 4-6 months, older 10-12 months), using fNIRS in a new event-related design, as babies processed linguistic phonetic (Native English, Non-Native Hindi) and nonlinguistic Tone stimuli. We found that phonetic processing in bilingual and monolingual babies is accomplished with the same language-specific brain areas classically observed in adults, including the left superior temporal gyrus (associated with phonetic processing) and the left inferior frontal cortex (associated with the search and retrieval of information about meanings, and syntactic and phonological patterning), with intriguing developmental timing differences: left superior temporal gyrus activation was observed early and remained stably active over time, while left inferior frontal cortex showed greater increase in neural activation in older babies notably at the precise age when babies’ enter the universal first-word milestone, thus revealing a first-time focalbrain correlate that may mediate a universal behavioral milestone in early human language acquisition. A difference was observed in the older bilingual babies’ resilient neural and behavioral sensitivity to Non-Native phonetic contrasts at a time when monolingual babies can no longer make such discriminations. We advance the “Perceptual Wedge Hypothesis” as one possible explanation for how exposure to greater than one language may alter neural and language processing in ways that we suggest are advantageous to language users. The brains of bilinguals and multilinguals may provide the most powerful window into the full neural “extent and variability” that our human species’ language processing brain areas could potentially achieve. 相似文献
165.
Jonathan Brennan Yuval NirUri Hasson Rafael MalachDavid J. Heeger Liina Pylkkänen 《Brain and language》2012,120(2):163-173
The neural basis of syntax is a matter of substantial debate. In particular, the inferior frontal gyrus (IFG), or Broca’s area, has been prominently linked to syntactic processing, but the anterior temporal lobe has been reported to be activated instead of IFG when manipulating the presence of syntactic structure. These findings are difficult to reconcile because they rely on different laboratory tasks which tap into distinct computations, and may only indirectly relate to natural sentence processing. Here we assessed neural correlates of syntactic structure building in natural language comprehension, free from artificial task demands. Subjects passively listened to Alice in Wonderland during functional magnetic resonance imaging and we correlated brain activity with a word-by-word measure of the amount syntactic structure analyzed. Syntactic structure building correlated with activity in the left anterior temporal lobe, but there was no evidence for a correlation between syntactic structure building and activity in inferior frontal areas. Our results suggest that the anterior temporal lobe computes syntactic structure under natural conditions. 相似文献
166.
Previous studies have found a late frontal-central audiovisual interaction during the time period about 150-220 ms post-stimulus. However, it is unclear to which process is this audiovisual interaction related: to processing of acoustical features or to classification of stimuli? To investigate this question, event-related potentials were recorded during a words-categorization task with stimuli presented in the auditory-visual modality. In the experiment, congruency of the visual and auditory stimuli was manipulated. Results showed that within the window of about 180-210 ms post-stimulus more positive values were elicited by category-congruent audiovisual stimuli than category-incongruent audiovisual stimuli. This indicates that the late frontal-central audiovisual interaction is related to audiovisual integration of semantic category information. 相似文献
167.
Gow DW 《Brain and language》2012,121(3):273-288
Current accounts of spoken language assume the existence of a lexicon where wordforms are stored and interact during spoken language perception, understanding and production. Despite the theoretical importance of the wordform lexicon, the exact localization and function of the lexicon in the broader context of language use is not well understood. This review draws on evidence from aphasia, functional imaging, neuroanatomy, laboratory phonology and behavioral results to argue for the existence of parallel lexica that facilitate different processes in the dorsal and ventral speech pathways. The dorsal lexicon, localized in the inferior parietal region including the supramarginal gyrus, serves as an interface between phonetic and articulatory representations. The ventral lexicon, localized in the posterior superior temporal sulcus and middle temporal gyrus, serves as an interface between phonetic and semantic representations. In addition to their interface roles, the two lexica contribute to the robustness of speech processing. 相似文献
168.
The present study aimed to refine current hypotheses regarding thematic reversal anomalies, which have been found to elicit either N400 or - more frequently - “semantic-P600” (sP600) effects. Our goal was to investigate whether distinct ERP profiles reflect aspectual-thematic differences between Agent-Subject Verbs (ASVs; e.g., ‘to eat’) and Experiencer-Subject Verbs (ESVs; e.g., ‘to love’) in English. Inanimate subject noun phrases created reversal anomalies on both ASV and ESV. Animacy-based prominence effects and semantic association were controlled to minimize their contribution to any ERP effects. An N400 was elicited by the target verb in the ESV but not the ASV anomalies, supporting the hypothesis of a distinctive aspectual-thematic structure between ESV and ASV. Moreover, the N400 finding for English ESV shows that, in contrast to previous claims, the presence versus absence of N400s for this kind of anomaly cannot be exclusively explained in terms of typological differences across languages. 相似文献
169.
Hesson J 《Brain and cognition》2012,80(1):89-95
This study looked at cumulative lifetime estrogen exposure, as estimated with a mathematical index (Index of Cumulative Estrogen Exposure (ICEE)) that included variables (length of time on estrogen therapy, age at menarche and menopause, postmenopausal body mass index, time since menopause, nulliparity and duration of breastfeeding) known to influence estrogen levels across the life span, and performance on prospective and retrospective memory measures in a group of 50 postmenopausal women (mean age=69.3years) who, if they were current or former users of estrogen therapy, had started therapy within 5years of menopause. The ICEE was found to be a significant predictor of performance on the Prospective Memory task (F(1)=4.21, p=.046, η(p)(2)=.084). No significant relationship was noted between the ICEE and performance on measures of retrospective memory. The results suggest that the level of cumulative lifetime exposure to estrogen a woman has influences her prospective memory performance later in life and that the influence of reproductive and biological markers of endogenous estrogen exposure are relevant factors to consider when studying the effect of estrogen therapy on cognitive functioning in postmenopausal women. In addition, the finding that performance on a measure of prospective memory, but not performance on measures of retrospective memory, was associated with the ICEE adds further support to the theory that the frontal cortex may be especially sensitive to estrogen. 相似文献
170.
Impairment on standard tests of delayed recall is often already maximal in the aMCI stage of Alzheimer's Disease. Neuropathological work shows that the neural substrates of memory function continue to deteriorate throughout the progression of the disease, hinting that further changes in memory performance could be tracked by a more sensitive test of delayed recall. Recent work shows that retention in aMCI patients can be raised well above floor when the delay period is devoid of further material - 'Minimal Interference'. This memory enhancement is thought to be the result of improved memory consolidation. Here we used the minimal interference/interference paradigm (word list retention following 10 min of quiet resting vs. picture naming) in a group of 17 AD patients, 25 aMCI patients and 25 controls. We found (1) that retention can be improved significantly by minimal interference in patients with aMCI and patients with mild to moderate AD; (2) that the minimal interference paradigm is sensitive to decline in memory function with disease severity, even when performance on standard tests has reached floor; and (3) that this paradigm can differentiate well (80% sensitivity and 100% specificity) between aMCI patients who progress and do not progress to AD within 2 years. Our findings support the notion that the early memory dysfunction in AD is associated with an increased susceptibility to memory interference and are suggestive of a gradual decline in consolidation capacity with disease progression. 相似文献