复发转移性乳腺癌患者血浆VEGF水平的临床价值研究

探讨血浆血管内皮生长因子（P-VEGF）在乳腺癌术后复发转移患者中的表达情况及临床意义。采用酶联免疫吸附试验检测50例术后复发转移性乳腺癌患者及20例乳腺良性疾病对照组的P-VEGF含量,同期采用微粒子化学发光法检测术后复发转移性乳腺癌患者血清CEA和CA15-3的表达情况,进行对比研究。结论认为转移肿瘤细胞可产生大量...     

大学生学习动机问卷的初步编制

本研究结合开放式问卷所获资料,在文献研究的基础上建构了大学生学习动机的维度,编制了大学生学习动机问卷,并将之施测于427名大学生。问卷的因素分析结果表明：（1）大学生学习动机归并为求知兴趣、能力追求、声誉获取和利他取向四个维度;（2）自编大学生学习动机问卷的信度和效度指标均达到了心理测量学要求。     

低出生体重与代谢综合征

低出生体重是发生成年期代谢综合征的高危因素。“代谢程序化”与“营养程序化”概念的提出对人们从多层面认识该现象的内在机制有重要指导作用。随着对发生机制研究的深入,人们终将找到预防低出生体重发生成年期代谢综合征的早期干预措施。     

A comparative assessment of the factor structures and psychometric properties of the GHQ-12 and the GHQ-20 based on data from a Finnish population-based sample

The General Health Questionnaire (GHQ) is a self-report questionnaire designed to identify psychological distress. Psychometric properties of two versions of GHQ-12 and GHQ-20 were assessed in a large population-based sample of Finnish twins, ages 22 to 27 (n= 4580). Participants were randomized into two subgroups, namely Twin1 (n= 2294) and Twin2 (n= 2286). The GHQ-12 data were assessed using Confirmatory Factor Analysis (CFA). The factor structure of the GHQ-20 was first assessed with Exploratory Factor Analysis (EFA) in the Twin1 dataset, and the results obtained were then subjected to CFA in Twin1 and Twin2 datasets. The CFA of the GHQ-12 indicated that the best fit and the simplest solution were provided by the three-factor solution in both subpopulations. Analyses of the GHQ-20 suggested that the four-factor structure was superior to the three-factor model. This result is also theoretically justifiable. Compared to the 12-item version, GHQ-20 provides additional fourth factor of anhedonia, suggesting some discriminative power.     

Health and Aging: A Perspective from the Far East

Singapore is an urban, highly industrialized country in South East Asia. By 2030, one-fifth of the population is projected to be composed of citizens aged above 65 years. Research on aging has largely focused on the effects of deteriorating physical ability on daily functioning capabilities (Iwarsson & Isacsson, 1997; Warr, 1995). More recently, the role of self-perceived usefulness, competence and control on well-being in the elderly have been investigated (Heberlein, Licht & Licht, 1999; Ranzjin, Keeves, Luszcz, & Feather, 1998). In other fields, activity and involvement have been identified as effective coping devices (Nair, 1989; Shalit, 1988). The present study compared the conceptual understanding of the esteem and well-being of the elderly on the dimensions of activity, involvement, and control, as viewed by an undergraduate sample (n = 60) and a cross-section of seniors (n = 71). Three separate factor analyses reflected interesting variations in the conceptual frameworks.     

Dimensions of fatigue in different working populations

Perceived fatigue related to work has often been measured in one dimension. The main purpose of the present study was to validate a proposed five-factor model of perceived fatigue in a new sample. 597 persons, employed in five occupations with different types of work loads, rated their fatigue after work. The ratings were subjected to analyses of linear structural equation models. The results suggest a slightly revised model for perceived fatigue, still with the five dimensions: Lack of energy, Physical exertion, Physical discomfort, Lack of motivation and Sleepiness. As expected, the rating profiles describing fatigue states differed between the five occupations. On the basis of these results, a revised version of the Swedish Occupational Fatigue Inventory (SOFI) is presented.     

影响竞技运动教练员工作倦怠的工作特征因素研究

通过文献分析和对28名竞技运动教练员进行半结构化的访谈,发现影响竞技运动教练员工作倦怠的工作特征因素包括角色冲突和角色模糊,工作任务过重,工作时间太长,长期不能和家人生活在一起,缺少领导和同事的支持,工作中的人际消耗与冲突,缺乏自主,缺少资源,工作时间模糊等。     

《大学生主观幸福感量表》的编制

根据国内外关于主观幸福感的文献和已有的研究经验,编制了大学生主观幸福感问卷。以往大多数研究认为,主观幸福感由生活满意度和情绪体验两个基本成分构成,本研究认为主观幸福感还应包括社会性行为和人际关系等成分。对376名大学生进行初测,通过探索性因素分析,表明大学生主观幸福感由自我满意、家庭满意、消极情绪、积极情绪、精力、生活满意、社会性行为和人际关系8个维度构成,共41个项目。对511名大学生施测41个项目的主观幸福感问卷,进行验证性因素分析,结果表明,上述结构是合理的。     

Transcultural validation and reliability of the Spanish version of the behaviour of young novice drivers scale (BYNDS) in a Colombian young driver population

The overrepresentation of young drivers in road crashes, and the fatalities and injuries arising from those crashes, is an intractable problem around the world. A plethora of research has led to the development and application of a range of research tools, including self-report survey instruments. One such instrument, the five-factor Behaviour of Young Novice Driver Scale (BYNDS), was developed in an Australian young driver population, and has recently been validated in a New Zealand young driver population. The current study aimed to validate the BYNDS in a Colombian young driver population, the first application of the instrument in a developing country. Translation from English to Spanish, and back translation from Spanish to English, in addition to culturally-appropriate modifications (such as changing ‘right hand side’ to ‘left hand side’) resulted in a Spanish version of the BYNDS (BYNDS-Sp). The BYNDS-Sp was administered to a sample of 392 young drivers aged 16–24 years (n = 353 aged 19–24 years) with a valid driver’s licence. An exploratory factor analysis revealed a six factor structure using 40 of the original 44 BYNDS-Sp items, accounting for 58.5% of the variance in self-reported risky driving behaviour. Ninety-three percent of participants reported having ready access to their own vehicle (42% owned their own vehicle), with Colombian young drivers most likely to report driving at night and on the weekend. The majority of participants reported driving in excess of posted speed limits (e.g., only one third of participants reported never driving 10–20 km/h over the speed limit), and driving in response to their mood (e.g., only one third of participants reported they never drove faster if in a bad mood). As such, the BYNDS-Sp can reveal patterns of problematic behaviours (such as risky driving exposure), in addition to specific behaviours of concern (such as carrying passengers at night, and driving when tired), guiding the development and implementation of interventions targeting the risky driving behaviour of young drivers in Colombia. In addition, the BYNDS-Sp can be used as a measure of intervention success if used as a baseline and as a follow-up tool. Further research can investigate the utility and applicability of the BYNDS-Sp in other Spanish-speaking countries, such as Spain and Mexico.     

教与学的大脑：人际神经科学助推教育研究

如何从神经生理层面刻画教育活动的人际互动模式和动态性是教育神经科学面临的一个重要挑战。人际神经科学视角为其提供了可能的解决途径; 这一新兴的视角通过记录和分析进行同一认知活动时两人或多人大脑活动之间的关联, 来揭示大脑活动的群体模式。目前, 人际神经科学方法已被应用于教育研究, 例如监控教学过程、预测教学效果和识别教学影响因素, 相应的研究成果对教育活动具有重要启示。未来的研究者可以更多地关注不同学习水平的学生大脑的互动机制及人际神经科学方法应用于技能教学及线上教学评估的巨大潜力。