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41.
Ziegler W 《Brain and language》2002,80(3):556-575
This study was focused on the potential influence of task-related factors on oral motor performance in patients with speech disorders. Sentence production was compared with a nonspeech oral motor task, i.e., oral diadochokinesis. Perceptual and acoustic measures of speech impairment were used as dependent variables. Between-task comparisons were made for subsamples of a population of 140 patients with different motor speech syndromes, including apraxia of speech and cerebellar dysarthria. In a further analysis subgroups were matched for speaking rate. Overall, dysdiadochokinesis was correlated with the degree of speech impairment, but there was a strong interaction between task type and motor speech syndrome. In particular, cerebellar pathology affected DDK to a relatively greater extent than sentence production, while apraxic pathology spared the ability of repeating syllables at maximum speed. 相似文献
42.
Neuronal changes in normal human aging and Alzheimer's disease 总被引:8,自引:0,他引:8
This article discusses age-related changes in brain weight, total number of cortical neurons, cortical dendrites, spine, and synapse density. The conclusion is that the present outlook is less grim than it was 30 years ago. Age-related reduction appears to be specific to brain region and cortical layer rather than a general feature. In addition, we describe a different pattern of changes that occur in Alzheimer's disease patients. This review concludes that the association cortices in particular are affected in aging and Alzheimer's disease and that the primary visual and somatosensory cortices are relatively spared. 相似文献
43.
Sixteen right-handed participants (8 male and 8 female students) and 16 left-handed participants (8 male and 8 female students) were presented with cartoon faces expressing emotions ranging from extremely positive to extremely negative. A forced-choice paradigm was used in which the participants were asked to rate the faces as either positive or negative. Compared to men, women rated faces more positively, especially in response to right visual field presentations. Women rated neutral and mildly positive faces more positively in the right than in the left visual field, whereas men rated these faces consistently across visual fields. Handedness did not affect the ratings of emotion. The data suggest a positive emotional bias of the left hemisphere in women. 相似文献
44.
Based on Schmidt's (1975) variability of practice hypothesis, this study examined acquisition and transfer of a gross motor skill, namely tossing, in 58 patients with Alzheimer's disease (AD) and 58 healthy older adults under constant, blocked, and random practice conditions. While healthy older adults were able to learn the tossing task equally well under the three practice conditions, only AD patients receiving constant practice showed significant improvements. Tests of intermediate transfer yielded the expected random practice advantage in healthy controls but not AD patients. None of the practice conditions facilitated intermediate transfer in AD patients; however, constant practice did benefit these impaired individuals on tests of near transfer. These results indicate that the variability of practice hypothesis does not extend to AD patients. As motor learning and transfer were clearly a function of constant practice, future attempts to retrain basic activities of daily living in AD patients should emphasize consistency in training. 相似文献
45.
Smith CU 《Brain and cognition》2001,46(3):364-372
J. C. Eccles (1903-1997) had a highly distinguished career in neurophysiology, being awarded the Nobel Prize for Medicine or Physiology in 1963. This paper sets him within the Cartesian tradition of British neurophysiology initiated by Thomas Henry Huxley in the mid-19th century. It shows how the mind-brain problematique of the Cartesian tradition troubled him throughout his career, leading him finally to a solution in terms of quantum microphysics and microphysiology. This position, which has subsequently become fashionable, is discussed and shown (at least in the form Eccles espoused) to provide no solution to the problem posed by Descartes in the early 17th century. 相似文献
46.
GY, an extensively studied human hemianope, is aware of salient visual events in his cortically blind field but does not call this "vision." To learn whether he has low-level conscious visual sensations or whether instead he has gained conscious knowledge about, or access to, visual information that does not produce a conscious phenomenal sensation, we attempted to image process a stimulus s presented to the impaired field so that when the transformed stimulus T(s) was presented to the normal hemifield it would cause a sensation similar to that caused by s in the impaired field. While degradation of contrast, spatio-temporal filtering, contrast reversal, and addition of smear and random blobs all failed to match the response to a flashed bar s(f), moving textures of low contrast were accepted to match the response to a moving contrast-defined bar, s(m). Orientation and motion direction discrimination of the perceptually matched stimuli [s(m) and T(s(m))] was closely similar. We suggest that the existence of a satisfactory match indicates that GY has phenomenal vision. 相似文献
47.
Despite considerable speculation in the research literature regarding the complementarity of functional lateralization of prosodic and linguistic processes in the normal intact brain, few studies have directly addressed this issue. In the present study, behavioral laterality indices of emotional prosodic and traditional linguistic speech functions were obtained for a sample of healthy young adults, using the dichotic listening method. After screening for adequate emotional prosody and linguistic recognition abilities, participants completed the Fused Rhymed Words Test (FRWT; Wexler & Halwes, 1983) and the Dichotic Emotion Recognition Test (DERT; McNeely & Netley, 1998). Examination of the difference in ear asymmetries for these measures within individuals revealed a complementary pattern in 78% of the sample. However, the correlation between laterality quotients for the FRWT and DERT was near zero, supporting Bryden's model of "statistical" complementarity (e.g., Bryden, 1990). 相似文献
48.
The research reported here focuses on the early acquisition of event structure in German. Based on longitudinal studies from 5 normally developing (ND) and 6 language-impaired (LI) children, a model of "event structural bootstrapping" is presented that spells out how ND children log into the verb lexicon. They project a target-consistent event tree, depicting the head-of-event of transitions. Young LI children, failing to employ this bootstrapping strategy, resort to radically underspecified event representations. The results from a truth-value judgment experiment with 16 ND and 16 LI children showed that ND children perform correctly on transitional verbs, while LI children perform at chance level on the same tasks. These findings are accounted for by the model of event structural bootstrapping to the extent that LI children lack an explicit representation of the head-of-event. 相似文献
49.
Tsimpli IM 《Brain and language》2001,77(3):432-448
This paper includes (i) a comparison of the developmental pattern of certain morphosyntactic features in normally developing (ND) Greek children with similar data from a group of children with specific language impairment and (ii) a new analysis of the differences found. The analysis is based on a minimalist notion of LF interpretability. Depending on the feature-specification of lexical items (i.e., [+/- interpretable] at LF), a different route of development follows. In addition, phonological salience of both interpretable and noninterpretable features is argued to play an important role in an account of crosslinguistic differences in both normal and exceptional development. 相似文献
50.
《Metaphilosophy》1999,30(3):231-259
Books reviewed:
Jonathan Lear, Open Minded: Working Out the Logic of the Soul
John P. Burgess and Gideon Rosen, A Subject with No Object; Strategies for Nominalistic Interpretation of Mathematics
Stewart Shapiro, Philosophy of Mathematics: Structure and Ontology
Patrick Grim, Gary Mar and Paul St. Denis, The Philosophical Computer
Noël Carroll, A Philosophy of Mass Art
Robert Eliot, Faking Nature: The Ethnics of Environmental Restoration 相似文献
Jonathan Lear, Open Minded: Working Out the Logic of the Soul
John P. Burgess and Gideon Rosen, A Subject with No Object; Strategies for Nominalistic Interpretation of Mathematics
Stewart Shapiro, Philosophy of Mathematics: Structure and Ontology
Patrick Grim, Gary Mar and Paul St. Denis, The Philosophical Computer
Noël Carroll, A Philosophy of Mass Art
Robert Eliot, Faking Nature: The Ethnics of Environmental Restoration 相似文献