Comprehension of gerundive constructions by Broca's aphasics

Eleven diagnosed Broca's aphasics were tested for comprehension of sentences containing gerundive constructions. Results showed that, as a group, these patients were sensitive to grammatical distinctions signaled by “function” words, contrary to the predictions of some current theories about the specific deficits exhibited in this syndrome. Further analysis showed that the patients fell into two subgroups, one which exhibited sensitivity to the distinctions in normal grammar, and another which exhibited no sensitivity to such distinctions. This suggests that the syndrome may have different manifestations in different populations—patient age is suggested as a possible means for distinguishing the two groups. Suggestions for further research into the nature of the comprehension deficits exhibited by Broca's aphasics are made.     

Depression in aphasic patients: Frequency, severity, and clinical-pathological correlations

Twenty-five hospitalized nonfluent, fluent, and global aphasic patients who were several months past the onset of their illness were compared for presence and severity of depression based on four psychopathological measures. The nonfluent aphasic patients had both greater frequency and severity of depression than the other two groups. CT scans showed that the global aphasic patients had the largest lesion size (volumetric) and showed a strong correlation between lesion size and degree of depression. In contrast, patients with fluent aphasias showed an inverse correlation between severity of depression and lesion size; among the nonfluent aphasic patients there was no significant correlation. Depression appears to be common in this population of hospitalized aphasic patients with chronic illness and nonfluent patients are the most depressed group within this population. The increased frequency and severity of depression in the nonfluent patients did not appear to be related to their overall physical or cognitive impairment; two possible mechanisms are discussed.     

General Learned Irrelevance and Its Prevention

Random presentation of a tone and an electric shock to rats interfered with subsequent acquisition of a light–shock association. This interference, or “general learned irrelevance” phenomenon, however, could be prevented by prior learning of a positive relationship between the tone and the shock or that between a noise and the shock. These results strongly support the ideas that animals learn irrelevant stimulus relationships and that prior experience of stimulus relevance prevents learning irrelevance. The similarity of this observed prevention effect to an immunization effect on learned helplessness phenomena is discussed.     

Why do Alzheimer patients have difficulty with pronouns? Working memory, semantics, and reference in comprehension and production in Alzheimer's disease

Three experiments investigated the extent to which semantic and working-memory deficits contribute to Alzheimer patients' impairments in producing and comprehending referring expressions. In Experiment 1, the spontaneous speech of 11 patients with Alzheimer's disease (AD) contained a greater ratio of pronouns to full noun phrases than did the spontaneous speech produced by 9 healthy controls. Experiments 2 and 3 used a cross-modal naming methodology to compare reference comprehension in another group of 10 patients and 10 age-matched controls. In Experiment 2, patients were less sensitive than healthy controls to the grammatical information necessary for processing pronouns. In Experiment 3, patients were better able to remember referent information in short paragraphs when reference was maintained with full noun phrases rather than pronouns, but healthy controls showed the reverse pattern. Performance in all three experiments was linked to working memory performance but not to word finding difficulty. We discuss these findings in terms of a theory of reference processing, the Informational Load Hypothesis, which views referential impairments in AD as the consequence of normal discourse processing in the context of a working memory impairment.     

A Cross-Cultural Study of Response Biases in Personality Measures

The purposes of this study were to (a) compare the response bias tendencies of U.S. and Philippine college students and men and women in each culture when responding to personality measures, (b) examine the comparability of different measures of the same response biases, (c) examine the stability or consistency of response biases across instruments, (d) examine the extent to which controlling for response biases affects cultural mean comparisons in personality variables, and (e) test hypothesized personality correlates of response biases. The results did not support the presence of large cross-cultural or gender differences in response biases. Moderate to high agreement was found between different indexes of the same biases. Participants' response bias tendencies were moderately stable across instruments. Controlling for response biases led to trivial changes in effect sizes; in most cases, conclusions about cultural differences in personality constructs did not change. Most hypotheses relating personality variables to response biases were not supported.     

Sex differences in functional cerebral asymmetries in a repeated measures design

The aim of the present study was to analyze whether task repetitions which are an inevitable part of repeated measures designs might induce performance alterations specific for gender and hemisphere. Male and female subjects conducted twice a lexical decision, a polygon recognition, and a face discrimination task as a visual half field paradigm with the two experimental sessions repeated by 2 weeks. The results show that only in female subjects can a session effect for the lexical decision and the polygon recognition task be demonstrated which is hemisphere specific. Thus, repeated measures designs seem to have a gender- and hemisphere-specific effects of their own which could confound with other variables under study.     

Dopamine and the origins of human intelligence

A general theory is proposed that attributes the origins of human intelligence to an expansion of dopaminergic systems in human cognition. Dopamine is postulated to be the key neurotransmitter regulating six predominantly left-hemispheric cognitive skills critical to human language and thought: motor planning, working memory, cognitive flexibility, abstract reasoning, temporal analysis/sequencing, and generativity. A dopaminergic expansion during early hominid evolution could have enabled successful chase-hunting in the savannas of sub-Saharan Africa, given the critical role of dopamine in counteracting hyperthermia during endurance activity. In turn, changes in physical activity and diet may have further increased cortical dopamine levels by augmenting tyrosine and its conversion to dopamine in the central nervous system (CNS). By means of the regulatory action of dopamine and other substances, the physiological and dietary changes may have contributed to the vertical elongation of the body, increased brain size, and increased cortical convolutedness that occurred during human evolution. Finally, emphasizing the role of dopamine in human intelligence may offer a new perspective on the advanced cognitive reasoning skills in nonprimate lineages such as cetaceans and avians, whose cortical anatomy differs radically from that of primates.     

The Humanizing Brain: A Clinician/Pastor Response

The Humanizing Brain is an effort by theological scholars to integrate neuroscience and theological constructs into a cohesive evolutionary and developmental scheme. The primary strength is a developing dialogue between neurodevelopmental theory and process theology. The book's widest appeal should be to theologians exploring religious and spiritual manifestations in the brain and neurosciences. The relatively simplistic science may limit significant usefulness to broad neuroscientific and medical communities, although neuroscientists and sophisticated lay readers with interests and back-grounds in theology may find The Humanizing Brain quite informative and interesting.     

Cognitive complexity and the similarity-attraction paradigm

The study investigated the role of cognitive complexity as a moderator of the similarity-attraction relationship described by Byrne (1971). Subjects conducted face-to-face interviews with confederates who played roles as job applicants. Similarity-dissimilarity was manipulated by the confederate roles, as well as by the information given the subjects in accordance with the procedures described by Byrne (1971). The situation was viewed as one in which judgments were made about a complex, multidimensional stimulus. Information received about another person in an interview setting was viewed as consisting of different dimensions to be assessed by the perceiver. The hypothesis was tested and confirmed that cognitively complex judges were more likely than simple judges to perceive and evaluate similarity/dissimilarity in others. Thus, complex judges evaluated similar applicants more positively than dissimilar applicants, while no differences were found for simple judges. Cognitive complexity thus appears to moderate the “Law of Attraction” described by Byrne (1971).     

Risky decision: Attention effects or masking effects?

The Marshak bid procedure shows that more money is required to induce a S to exchange gamble a for gamble e and then e for b if e differs from a only in the winning amount and differs from b only in the probability of winning, rather than if e differs from a only in the probability of winning. This is contrary to most theories of risky decision making which imply that the amount of money necessary to effect a 2-step exchange between a and b should be independent of the intermediary gamble. One might attempt to explain the effect by saying that the S attends to the dimension which is different between gambles. But the explanation is untenable if one assumes that states of attention are defined as weightings of the dimensions. An alternative explanation is put forward which basically assumes that winning amounts mask differences in probability of winning more than vice versa. The formalization of the theory is given in terms of Fechnerian integration over imperfect differentials.